Clinical Trials

Genetic and Environmental Risk Factors for PSP

Description

Status: Open to Enrollment

Start Date: Sep 30 2010

End Date: OPEN

This study will determine:

(1) if there is an association between PSP and specific genes of interest;

(2) if there is an association between PSP and occupational and/or environmental chemical exposures functionally or structurally similar to known parkinsonian toxicants;

(3) if hypertension or traumatic brain injury prior to symptom-onset is associated with PSP

A. PSP Cases:
  • Patient must be diagnosed with PSP (Progressive supranuclear palsy)
  • Patient must be new to the site and the site PI or were evaluated by the Site PI for the first time within the past year.
  • Patient must be 40 years of age or older
  • Patient must be able to visit the screening site to be evaluated by a movement disorder specialist.
  • Patient must speak well enough to complete a telephone interview regarding his/her life history
  • Patient must have no other major neurological disorders
  • Patient must have a spouse or primary caregiver and an age/gender-matched, non-blood relative or neighbor who are willing to participate as controls in the study
B. Control 1:
  • Must not have diagnosis of Parkinson’s or a related disease.
  • Age (±5 years) and gender matched non-blood relative of the case (i.e. Inlaws)
  • OR Age (±5 years) and gender matched non-blood friend or neighbor
C. Control 2:
  • Must not have diagnosis of Parkinson’s or a related disease.
  • Age matched control (±5 years) of the case (i.e. case’s spouse or primary caregiver)
  • OR Age matched (±5 years) non-blood relative

Principal Investigators

David Shprecher , D.O.

Co Investigators

Lauren Schrock, M.D.

Contact Information

Name: Paola
Phone: 801.581.4543
Email: paola.wall@hsc.utah.edu

Please Note:

Study Coordinators and Research Nurses cannot give medical advice over the phone. Telephone numbers are provided for obtaining additional information on specific clinical research trials only. If you have specific questions which require clinical expertise, please call your primary care physician. If you do not have a primary care physician, we can help you find a University of Utah doctor or clinic location to meet your health care needs.

Although the studies described on this Web site may have potential benefits as described, the University of Utah and its physicians and affiliated hospitals cannot and do not guarantee or promise that you will receive any benefits from participating in a study.

The information posted on this site is consistent with the research reviewed and approved by the University of Utah Institutional Review Board (IRB). However, the IRB has not reviewed all material posted on this site. Contact the IRB if you have questions regarding your rights as a research participant. Also contact the IRB if you have questions, complaint, or concerns which you do not feel you can discuss with the investigator. The University of Utah IRB may be reached by phone at (801) 581-3655 or by e-mail at irb@hsc.utah.edu.