Status:Active, not recruiting
Keywords:IUD , Birth Control
Sub Specialty:General Obstetrics
This project is designed to investigate the changes in female genital tract bacterial ecology and inflammatory markers associated with LNG IUD use.
The research hypothesis is that placement of the LNG IUD will result in changes of the bacterial communities as well as inflammatory markers in the female genital tract including the vagina, cervix and uterus.
Participants will be women who are already anticipating an IUD placement. Vaginal cervical and uterine fluid samples will be collected at various timepoints before and after the IUD insertion.
Extra tissue samples will be stored for future investigations if pt consents to storage of coded samples.
Reproductive Age Caucasian Females 18 to 45 years old:
1. Not pregnant
2. No use of hormonal birth control in the last 3 months
3. Desiring Levonorgestrel IUD
4. Greater than 6 months post partum
5. Greater than 6 weeks after miscarriage
6. No use of antibiotics in previous 6 weeks.
1. Uterine abnormalities
2. Current hormonal contraception use or use in the past 3 months
3. Unexplained vaginal bleeding
4. Cervical Dysplasia
5. Irregular menses
6. Cervical or vaginal infection in the past 6 weeks.