Rotation Study


Status: Enrolling by invitation
Keywords: Pediatrics , Rotational malalignment , MRI , Femoral version , Tibial torsion
IRB Number: 00051477
Specialty: Orthopaedic Surgery, Radiology, Orthopaedic Surgery, Radiology
Sub Specialties: Pediatric Imaging, Orthopaedic Trauma, Magnetic Resonance Imaging – MRI

Brief Summary

Rotational deformities of the lower extremity is a frequent reason to see the care of a pediatric orthopaedist. Though most children self-correct this finding by age 10, many do not and a subset of these patients develop knee pain or instability. We routinely measure rotational profiles in clinic, but if a patient is considering surgery we will obtain cross-sectional imaging to define their rotation. In the pediatric population this is frequently MRI and we have seen disparaging data clinically and radiographically. Our study has two arms: first we will retrospectively determine the inter-/intra-observer reliability of MRI to measure rotation of the femur and tibia.; second we will prospectively enroll patients presenting with rotational deformity warranting possible surgery to obtain MRI and compare to their clinical exam.

Principal Investigator: Stephen Aoki
Department: Orthopedic Surgery
Co Investigator: Thomas Higgins
Co Investigator: Peter Stevens
Co Investigator: Joshua Klatt

Contact Information

Name:Deveree Partridge
Phone: 801-213-4176

Inclusion Criteria

Inclusion for Retrospective:
•Prior study MRI images available in the University PACS system from 2009-current
•Prior study MRI images obtained at PCMC and uploaded into the OsiriX software (OsiriX is a software program compatible with multiple imaging formats that has easily adaptable measurement tools) from 2009-present
•All axial view MRI studies obtained at PCMC or the UOC for evaluation of rotational profile

Inclusion for Prospective:
•All patients of the investigating physicians, male and female, between the ages of 8 and 30 presenting with complaints of patellofemoral pain/instability or rotational abnormality
•All patients with neuromuscular disease, including cerebral palsy

Exclusion Criteria

Exclusion for Retrospective:
•Any imaging study insufficient to provide all of the required measurements and any patient previously surgically treated for rotational malalignment

Exclusion for Prospective:
•Any patient that has undergone previous surgical treatments for rotational malalignment.
•Any patients with implantable devices not compatible with MRI