Keywords:environmental toxins and female fertility
Sub Specialty:Women's Health
Our proposed study is designed to determine the developmental and reproductive toxicity of phthalates, Bisphenol A and other endocine disrupting chemicals, vascular endothelial growth factor (VEGF) and other molecules that may affect reproductive outcomes in couples undergoing assisted reproductive technologies. ART allows us to assess oocyte quality, fertilization rates, pre-implantation embryo development, and pre-clinical (early) pregnancy loss. These early developmental endpoints are not observable in women conceiving naturally, but are of high importance in deciphering the impact on reproductive function.
All Women age 18-42 undergoing in vitro fertilization at the Utah Center for Reproductive Medicine (UCRM) will be asked to participate in our study.