Status: Enrolling by invitation
Keywords: Hip Dysplasia , Hip preservation , Labral Tear
IRB Number: 00010983
Specialty: Orthopaedic Surgery, Orthopaedic Surgery
Sub Specialties: Periacetabular Osteotomy, Hip Preservation
This study will examine the biomechanics of the hip in normal and dysplastic patients, specifically focusing on patients with "traditional" dysplasia versus those with a dysplastic "retroverted" acetabulum. Patient-specific computer models will be used to predict contact areas, maximum cartilage stresses and maximum bone stresses and their locations for the three patient groups analyzed (normal, traditional dysplastic, retroverted dysplastic). CT athrography will be used to image each subject (contrast enhanced CT). Synovial fluid samples will be drawn from each subject during arthrography. The fluid will be analyzed to determine if biomarkers of osteoarthritis are present. If the subject agrees to the secondary study then motion analysis will be used to record the movements and kinematics during walking, stair climbing and descending stairs. These movements will be use to provide motion and loading data to the computational models on a patient-specific basis. Finally, an MRI scan, using a test protocol, will be obtained of all persons who consent to such. Models developed from the MR images will be compared to models developed from the CT images to determine if MRI could possibly be used in the future to replace CT for the purpose of generating finite element models of the hip joint. MRI is of interest to our group as it is non-invasive with regards to radiation exposure. Also, it is possible that the MRI protocol we seek to develop and test herein could replace existing clinical MR protocols for all patients with suspected hip dysplasia. Existing MR protocols are low resolution, do not afford good visualization of the two cartilage layers, and are not acquired using a 3D sequence.