Urine Acid Excretion in Chronic Kidney Disease (CKD)

Overview

Status: Recruiting
Keywords: chronic kidney disease , renal disease , kidney , observational , acid-base balance
IRB Number: 00060458
Specialty: Nephrology and Hypertension
Sub Specialties:

Brief Summary

Hypothesis: Urinary NH4+ excretion rate, as a measure of renal ammoniagenesis, is a risk factor for CKD progression and death.

Specific Aim: To determine if urinary NH4+ excretion rate is a risk factor for CKD progression in patients at the University of Utah with stages 3 and 4 CKD.

Principal Investigator: Kalani Raphael
Department: Nephrology
Co Investigator:

Contact Information

Name:Jennifer Zitterkoph
Phone: 801-585-1897
Email: jennifer.zitterkoph@hsc.utah.edu

Inclusion Criteria

1. Age older than 18 years

2. Stage 3 or 4 CKD (eGFR 15 - 59 ml/min/1.73musing the MDRD equation)

 

Exclusion Criteria

1. Presence of a urinary conduit, such as a neobladder or urostomy.

2. History of chronic urinary tract infections (for example > 3 per year, or requires chronic suppressive treatment).