MRI of High-Risk Carotid Plaque


Status: Recruiting
Keywords: Carotid Stenosis , Carotid Artery Disease , Magnetic Resonance Imaging
IRB Number: 00062898
Specialty: Vascular Surgery, Radiology
Sub Specialties:

Brief Summary

The purpose of this research study is to develop a carotid MR imaging protocol that can be used with the different imaging systems and then use this protocol to insure the images are uniform across these imaging systems.  This is a multi-site study that will include the University of Utah, University of California San Francisco, Michigan State University, Stanford University and the University of Washington.  These sites were selected because of different imaging systems that they regularly use for imaging patients and their expertise in this field of medicine. 

The U.S. Food and Drug Administration (FDA) has approved the equipment, software and contrast that will be used in this study.

Principal Investigator: Gerald Treiman
Department: Radiology Research
Co Investigator: Dennis Parker

Contact Information

Name:Kristi Carlston
Phone: (801) 585-6142

Inclusion Criteria

  1. 50% and greater carotid bifurcation stenosis on at least one side per recent imaging study

Exclusion Criteria

  1. Inability to provide informed consent
  2. Contraindication to MRI
  3. eGFR < 45mL/min/1.73m2
  4. History of allergy to gadolinium contrast
  5. Prior carotid surgery
  6. History of radiation therapy to the neck
  7. Pregnancy
  8. History of hepatorenal syndrome
  9. Histpry of liver transplantion
  10. Vascular stent placed within 8 weeks of MRI