MR Imaging of Small Vessels

Overview

Status: Recruiting
Keywords: Vasculitides , Scleroderma , Peripheral vasculature , Raynauds , Nail bed capillaroscopy , Photoplethysmography , Magnetic Resonance Imaging
IRB Number: 00063262
Specialty: Vascular Surgery, Rheumatology, Radiology
Sub Specialties: Magnetic Resonance Imaging – MRI

Brief Summary

Objectives

  1. To assess the validity of non-gadolinium techniques for evaluation of peripheral arteries as compared to conventional gadolinium MRA, nail bed capillaroscopy, and photoplethysmography.
  2. To assess the severity of arterial disease in patients with vasculitides, RP, or scleroderma, as compared to age-matched controls.
  3. To assess the peripheral arteries by non-gadolinium and gadolinium MRA, nail bed capilloaroscopy, and photoplethysmography while patients are on therapy compared to off therapy or before and after therapy, including pharmacologic or hyperbaric therapy.

Principal Investigator: Christopher Hanrahan
Department: Radiology Clinical
Co Investigator: Michelle Mueller
Co Investigator: Tracy Frech

Contact Information

Name:Kristi Carlston
Phone: (801) 587-8190
Email: mjb27@utah.edu

Inclusion Criteria

  1. Patients with peripheral arterial dysfunction due to Raynaud's phenomenon, scleroderma, vasculitis, or thermal injury along with age-matched control patients.
  2. Patients must be 18 years or older
  3. Must be able to lie in scanner for 1 to 1 1/2 hours

 

Exclusion Criteria

  1. Contraindications to MRI scanning
  2. Pregnant patients
  3. Acute or Chronic Kidney disease patients
  4. When available, estimated glomerular filtration rate below 60 mL/min/1.73m2