Keywords: Spinal Cord Injury (SCI) , Magnetic Resonance Imaging , Diffusion Tensor Imaging
IRB Number: 00063552
Specialty: Radiology, Neurosurgery, Radiology, Radiology, Radiology
Sub Specialties: Head and Neck Imaging, Neuroradiology, Magnetic Resonance Imaging – MRI
The aim of this project will be to determine the presence of reorganization in cortical motor neural networks following spinal cord injury (SCI) compared to healthy volunteers utilizing resting-state fMRI. Clinical correlations with ASIA impairment scale will also be performed. In addition, using diffusion tensor imaging (DTI) we hope to show that SCI will be associated with altered diffusion properties in the primary motor cortex, greatest in the region of primary motor cortex that innervates the paralyzed part of the body as well as in the descending corticospinal tract fibers, indicative of significant neural loss. Ultimately, these findings might be used to predict outcome in patients with traumatic spinal cord injury, identify neural substrates of complications such as phantom limb syndrome, and help to design more effective therapeutic strategies.
Phone: (801) 587-8190