Status: Not yet recruiting
Keywords: psoriasis , fingernail , excimer , laser
IRB Number: 00067130
Specialty: Dermatology, Dermatology
Sub Specialties: Laser and Cosmetic Dermatology, Psoriasis and Phototherapy
1. To assess the efficacy of 8 weeks of excimer laser in treating fingernail psoriasis in a randomized, blinded, right-left comparison trial. Due to slow growth rate of fingernails, final efficacy assessment will be performed at week 16.
a. To compare the mean improvement in target nail mNAPSI score [Modified Nail Psoriasis Severity Score] of excimer laser treated (EL) hand compared to sham treated hand.
b. To assess the proportion of patients achieving NAPSI 50 and NAPSI 75 (50% and 75% improvement, respectively) at week 16.
c. To assess the proportion of patients with no nail psoriasis (overall NAPSI sore of 0) at weeks 16.
d. To compare changes from baseline in physician’s and patient’s assessment of nail psoriasis activity [visual analogue scale (VAS); range of 0 (no nail disease) to 100 (worst possible nail disease)].
2. To assess the adverse events associated with excimer laser treatment of nail psoriasis.
a. To compare immediate and delayed symptoms in excimer treated fingers compared to sham treated fingers.
Name:Razieh Soltani - Arabshahi
Phone: 801 581 6465