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Douglas Grossman, M.D., Ph.D.

Associate Professor of Dermatology and Oncological Sciences

• B.S., magna cum laude, 1985, Duke University
• Ph.D., 1992, Baylor College of Medicine
• M.D., Alpha Omega Alpha 1994, Baylor College of Medicine
• Residency in Dermatology, 1995-1998, Yale University
• Fellowship in Cancer Biology, 1998-2000, Yale University
• Board Certification in Dermatology

Clinical and Research Interests

• Skin cancer: specializes in patients with melanoma, squamous cell carcinoma, basal cell carcinoma; and patients with family history of melanoma or multiple nevi (moles). Director of Mole Mapping program. Research areas include molecular aspects of melanoma and non-melanoma skin cancer with a focus on apoptosis (programmed cell death) in melanocyte and keratinocyte carcinogenesis, and the role of oxidative stress in melanoma.

Selected Publications

• Goodson AG, Florell SR, Boucher KM, Grossman D (in press): Low rates of clinical recurrence following biopsy of benign to moderately dysplastic melanocytic nevi. J Amer Acad Dermatol.

• Goodson AG, Grossman D (2009): Strategies for early melanoma detection: approaches to the patient with nevi (CME article). J Amer Acad Dermatol 60:719-735.

• Raj D, Liu T, Samadashwily G, Li F, Grossman D (2008): Survivin repression by p53, Rb, and E2F2 in normal human melanocytes.  Carcinogenesis 29:194-201.

• Cotter MA, Thomas J, Cassidy P, Robinette K, Jenkins N, Florell SR, Leachman SA, Samlowski WE, and Grossman D (2007): N-acetylcysteine protects melanocytes against oxidative stress/damage and delays onset of UV-induced melanoma in mice.  Clin Cancer Res 13:5952-5958.

• Fuller SR, Bowen GM, Tanner B, Florell SR, Grossman D (2007): Digital dermoscopic monitoring of atypical nevi in patients at risk for melanoma.  Dermatol Surg 33:1198-1206.

• Florell SR, Thomas J, Grossman D (2007): Predominant formation of heavily pigmented dermal melanocytomas resembling ‘animal-type’ melanomas in HGF (C57BL/6 x C3H)F₁ mice following neonatal UV irradiation.  J Cutan Pathol 34:667-674.

• Thomas J, Liu T, Cotter MA, Florell SR, Robinette K, Hanks AN, Grossman D (2007): Melanocyte expression of Survivin promotes development and metastasis of UV-induced melanoma in HGF transgenic mice.  Cancer Res 67:5172-5178.

• Cotter MA, Florell SR, Leachman SA, Grossman D (2007): Absence of senescence-associated beta-galactosidase activity in human melanocytic nevi in vivo. 

 Grossman Lab