Dermatology Services

Pemphigoid

Direct Immunofluorescence of Pemphigoid Skin Biopsy

Skin biopsy (perilesional) for direct immunofluorescence and serum for indirect immunofluorescence (IgG basement membrane zone antibodies) and ELISA for IgG BP 180 and BP 230 antibodies.

Bullous pemphigoid

Cicatricial pemphigoid:

  • Anti-epiligrin cicatricial pemphigoid
  • Brunsting-Perry pemphigoid
  • Ocular pemphigoid
  • Mucous membrane pemphigioid
  • Gestational pemphigoid, herpes gestationis or pemphigoid gestationis (also serum for herpes gestationis factor)
IgG cell surface (intercellular substance) staining (40x)
IgG linear basement membrane zone (20x)
C3 linear basement membrane zone (40x)
C3 linear basement membrane zone (40x)

Indirect Immunofluorescence of Pemphigoid Serum on Human Split Skin Substrate

IgG epidermal pattern (roof of split) (20x)
IgG linear basement membrane zone (20x)