Dermatology Services

Disease Images

Indirect Immunofluorescence of Pemphigus Serum in Calcium Buffer on Intact Human Skin
IgG cell surface (intercellular substance) staining (40x)

IgG cell surface (intercellular substance) staining (40x)

Direct Immunofluorescence of Pemphigoid Skin Biopsy
IgG linear basement membrane zone (20x) and C3 linear basement membrane zone (40x)
IgG cell surface (intercellular substance) staining (40x)   C3 linear basement membrane zone (40x)
Indirect Immunofluorescence of Pemphigoid Serum on Human Split Skin Substrate
IgG epidermal pattern (roof of split) (20x)
IgG epidermal pattern (roof of split) (20x)
Indirect Immunofluorescence of Epidermolysis Bullosa Acquisita Serum on Human Split Skin Substrate
IgG dermal pattern (floor of split) 
Indirect Immunofluorescence of Epidermolysis Bullosa Acquisita Serum on Human Split Skin Substrate

Indirect Immunofluorescence of Linear IgA Bullous Dermatosis Serum on Human Split Skin Biopsy
IgA epidermal pattern (roof of split) (40x)

LABD
Direct Immunofluorescence of Dermatitis Herpetiformis Skin Biopsy
IgA granular basement membrane zone with stippling in dermal papillae (40x)
Dermatitis Herpetiformis

Endomysial Antibody IgA Indirect Immunofluorescence of Serum on Human Umbilical Cord Substrate
Endomysium staining (40x)
Indirect Immunofluorescence of Eosinophil Granule Major Basic Protein in Urticaria Skin Biopsy
Direct Immunofluorescence of Lupus Erythematosus Skin Biopsy
(Lichenoid changes may also be observed)
C3 granular basement membrane zone (40x)
Lupus Erythematosus Skin Biopsy
 
Direct Immunofluorescence of Lichen Planus of Lichenoid Reaction Skin Biopsy
IgM scattered and clumped cytoids
Lichen Planus or Lichenoid Reactions
Direct Immunofluorescence of Cutaneous Vasculitis (including Urticarial Vasculitis) Skin Biopsy
Fibrinogen blood vessels (vessels may also stain for IgG, IgM, IgA and C3; IgA vascular staining is characteristic of Henoch Schönlein purpura)
Direct Immunofluorescence of Cutaneous Vasculitis (including Urticarial Vasculitis) Skin Biopsy
Direct Immunofluorescence of Porphyria or Pseudoporphyria Skin Biopsy
C3 granular and fibrinogen weak thick basement membrane zone and perivascular
Direct Immunofluorescence of Porphyria or Pseudoporphyria Skin Biopsy     Direct Immunofluorescence of Porphyria or Pseudoporphyria Skin Biopsy
Indirect Immunofluorescence of Eosinophil Granule Major Basic Protein in Urticaria Skin Biopsy
Few intact eosinophils and extensive extracellular granular major basic protein deposition
urticaria