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Matthew T. Rondina, M.D., M.S.

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  • English

Clinical Details

Schedule An Appointment Clinical Office Address
(801) 581-7790 Madsen Health Center
555 Foothill Blvd
Salt Lake City, UT 84112



Dr. Rondina was raised in Boston, Massachusetts and completed his medical school and residency training at the University of Utah. After completing a position as Chief Medical Resident, he joined the Department of Internal Medicine. Dr. Rondina is a Hospitalist and Co-Director of the University Healthcare Thrombosis Service. He helps care for hospitalized patients with acute medical conditions and outpatients with, or at-risk for, thrombotic disorders.

Board Certification and Academic Information

Academic Departments Internal Medicine - Associate Professor
Academic Divisions General Internal Medicine
Board Certification American Board of Internal Medicine (Internal Medicine)

Academic Profile

Board Certification and Academic Information

Academic Departments Internal Medicine - Associate Professor
Academic Divisions General Internal Medicine
Board Certification American Board of Internal Medicine (Internal Medicine)

Academic Office Locations

Academic Office Phone Number Academic Office Address
(801) 585-0950 George and Dolores Eccles Institute of Human Genetics
University Health Care - Internal Medicine
15 N 2030 E
Salt Lake City, UT 84112

Academic Bio

Dr. Rondina is currently the principal investigator on a K23 NIH Grant focused on understanding how platelet functions are altered in sepsis to promote thrombosis and an R03 grant from the National Institutes of Aging studying age-related changes in platelet and leukocyte signaling pathways. He has also been a co-investigators on multiple bench-to-bedside R01s identifying how dysregulated platelet functions contribute to inflammatory and thrombotic syndromes as a result of major surgery, acute bacterial and viral infections, diabetes, and obesity. Dr. Rondina’s work has received national and international recognition and contributed to improving our understanding of platelet functions. His work has been published in such journals as The Journal of Thrombosis and Haemostasis, Chest, and The Journal of Experimental Medicine.

Dr. Rondina recently received a Young Investigator Award from the American College of Chest Physicians and a New Investigator Award from the American Geriatric Society. In addition, he has served on NIH study section, mentored numerous young investigators from the University of Utah, Germany, and Brazil, and served as referee for journals such as the American Journal of Respiratory and Critical Care Medicine, The Journal of Thrombosis and Haemostasis, and Thrombosis and Haemostasis.

Dr. Rondina’s expertise in thrombotic and inflammatory disorders and his work uniting basic science and clinical research supports the mission of the University of Utah in providing cutting edge, personalized healthcare to our patients and advancing our understanding of how to prevent and treat thrombotic disorders.


Education History

Type School Degree
Graduate Training University of Utah
Clinical Investigation
Residency University of Utah Health Sciences Center
Internal Medicine
Internship University of Utah Health Sciences Center
Internal Medicine
Professional Medical University of Utah Medical School
Undergraduate University of Utah
Undergraduate Brigham Young University


Selected Provider Publications

Journal Article

  1. Rondina MT, Carlisle M, Fraughton T, Brown SM, Miller RR 3rd, Harris ES, Weyrich AS, Zimmerman GA, Supiano MA, Grissom CK (07/29/2014). Platelet-Monocyte Aggregate Formation and Mortality Risk in Older Patients With Severe Sepsis and Septic Shock. J Gerontol A Biol Sci Med Sci, In Press.
  2. Brown SM, Tate MQ, Jones JP, Kuttler KG, Lanspa MJ, Rondina MT, Grissom CK, Mathews VJ (2014). Coefficient of Variation of Coarsely Sampled Heart Rate is Associated With Early Vasopressor Independence in Severe Sepsis and Septic Shock. J Intensive Care Med.
  3. Mohebali D, Kaplan D, Carlisle M, Supiano MA, Rondina MT (2014). Alterations in Platelet Function During Aging: Clinical Correlations with Thromboinflammatory Disease in Older Adults.LID - 10.1111/jgs.12700 [doi]. J Am Geriatr Soc.
  4. Kline JA, Nordenholz KE, Courtney DM, Kabrhel C, Jones AE, Rondina MT, Diercks DB, Klinger JR, Hernandez J (2014). Treatment of submassive pulmonary embolism with tenecteplase or placebo: cardiopulmonary outcomes at three months (TOPCOAT): Multicenter double-blind, placebo-controlled randomized trial.LID - 10.1111/jth.12521 [doi]. J Thromb Haemost.
  5. Rondina MT, Weyrich AS, Zimmerman GA (2013 May 24). Platelets as cellular effectors of inflammation in vascular disease. Circ Res, 112(11), 1506-19.
  6. Chen K, Rondina MT, Weyrich AS (2013). A sticky story for signal transducer and activator of transcription 3 in platelets. Circulation, 127(4), 421-3.
  7. Kraemer BF, Campbell RA, Schwertz H, Franks ZG, Vieira de Abreu A, Grundler K, Kile BT, Dhakal BK, Rondina MT, Kahr WH, Mulvey MA, Blaylock RC, Zimmerman GA, Weyrich AS (2012). Bacteria differentially induce degradation of Bcl-xL, a survival protein, by human platelets. Blood, 120(25), 5014-20.
  8. Rondina MT, Lam UT, Pendleton RC, Kraiss LW, Wanner N, Zimmerman GA, Hoffman JM, Hanrahan C, Boucher K, Christian PE, Butterfield RI, Morton KA (2012). (18)F-FDG PET in the evaluation of acuity of deep vein thrombosis. Clin Nucl Med, 37(12), 1139-45.
  9. McInturff AM, Cody MJ, Elliott EA, Glenn JW, Rowley JW, Rondina MT, Yost CC (2012). Mammalian target of rapamycin regulates neutrophil extracellular trap formation via induction of hypoxia-inducible factor 1 alpha. Blood, 120(15), 3118-25.
  10. Freeman A, Horner T, Pendleton RC, Rondina MT (2012). Prospective comparison of three enoxaparin dosing regimens to achieve target anti-factor Xa levels in hospitalized, medically ill patients with extreme obesity. Am J Hematol, 87(7), 740-3.
  11. Rondina MT, Grissom CK, Men S, Harris ES, Schwertz H, Zimmerman GA, Weyrich AS (2012). Whole blood flow cytometry measurements of in vivo platelet activation in critically-Ill patients are influenced by variability in blood sampling techniques. Thromb Res, 129(6), 729-35.
  12. Rondina MT, Brewster B, Grissom CK, Zimmerman GA, Kastendieck DH, Harris ES, Weyrich AS (2012). In vivo platelet activation in critically ill patients with primary 2009 influenza A(H1N1). Chest, 141(6), 1490-5.
  13. Rondina MT, Wanner N, Pendleton RC, Kraiss LW, Vinik R, Zimmerman GA, Heilbrun M, Hoffman JM, Morton KA (2011). A pilot study utilizing whole body 18 F-FDG-PET/CT as a comprehensive screening strategy for occult malignancy in patients with unprovoked venous thromboembolism. Thromb Res, 129(1), 22-7.
  14. Rondina MT, Schwertz H, Harris ES, Kraemer BF, Campbell RA, Mackman N, Grissom CK, Weyrich AS, Zimmerman GA (2011). The septic milieu triggers expression of spliced tissue factor mRNA in human platelets. J Thromb Haemost, 9(4), 748-58.
  15. Johnson S, Rondina MT (2011). Local INR control had some effect on the benefits of dabigatran over warfarin for major bleeding in atrial fibrillation. ACP J Club, 154(2), JC1-6.
  16. Vazquez S, Rondina MT (2010). ACP Journal Club. Review: Graduated compression stockings reduce deep venous thrombosis in hospitalized patients. Ann Intern Med, 153(12), JC6-6.
  17. Freeman AL, Pendleton RC, Rondina MT (2010). Prevention of venous thromboembolism in obesity. Expert Rev Cardiovasc Ther, 8(12), 1711-21.
  18. Franks ZG, Campbell RA, Weyrich AS, Rondina MT (2010). Platelet-leukocyte interactions link inflammatory and thromboembolic events in ischemic stroke. Ann N Y Acad Sci, 1207, 11-7.
  19. Vazquez SR, Johnson SA, Rondina MT (2010). Peri-procedural anticoagulation in patients undergoing ablation for atrial fibrillation. Thromb Res, 126(2), e69-77.
  20. Rondina MT, Walker A, Pendleton RC (2010). Drug-induced thrombocytopenia for the hospitalist physician with a focus on heparin-induced thrombocytopenia. Hosp Pract (Minneap), 38(2), 19-28.
  21. Rondina MT, Wheeler M, Rodgers GM, Draper L, Pendleton RC (2010). Weight-based dosing of enoxaparin for VTE prophylaxis in morbidly obese, medically-ill patients. Thromb Res, 125(3), 220-223.

Book Chapter

  1. Rondina MT, Weyrich AS (2012). Targeting Phosphodiesterases in Anti-Platelet Therapy. In Gresele, P. (Ed.), Antiplatelet Agents, Handbook of Experimental Pharmacology (210, pp. 225-38). Berlin: Springer-Verlag.
  2. Harris ES, Rondina MT, Schwertz H, Weyrich AS, Zimmerman GA (2010). Pathogenesis of sepsis and sepsis-induced acute lung injury. In A.M.K. Choi (Ed.), Acute Respiratory Distress Syndrome, Second Edition (pp. 369-419). Informa Healthcare.


  1. Rondina MT, Lam UT, Pendleton RC, Kraiss LW, Wanner N, Zimmerman GA, Hanrahan C Boucher K, Hoffman M, Morton KA (04/22/2012). The role of 18-fluorine-fluorodeoxyglucose positron emission tomography in the evaluation of deep vein thrombosis [Abstract]. Thrombosis Research, 129(S1), S165.


  1. Schwertz H, Rondina MT, Weyrich AS (2014). Retinoic acid receptor alpha guides platelet actin cytoskeleton dynamics. Poster session presented at 8th International Platelet Symposium, Jerusalem, Israel.
  2. Schwertz HJ, Rondina MT, Weyrich AS (February 13, 2014). Retinoic Acid Receptor Alpha Guides Platelet Actin Cytoskeletal Dynamics (P22-5). Poster session presented at 58th Annual Meeting Society of Thrombosis and Haemostasis Research, Vienna, Austria.
  3. Rondina MT, Kalva S, Men S, Harris ES, Carlisle M, Zimmerman GA, Weyrich AS, Grissom CK (2012). Platelet-Monocyte Aggregate Formation and Cytokine Responses Correlate with Mortality in Elderly Septic Patients. Poster session presented at 2012 American Geriatric Society National Meeting, Seattle, WA.

Clinical Trials

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