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Nirupama Ramkumar, M.D., M.P.H.

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Specialties

Languages

  • English
  • Hindi
  • Tamil

Clinical Details

Phone Number Clinical Office Address
(801) 585-6320
University Hospital
Kidney and Liver Clinic
50 N Medical Dr , Suite A100
Salt Lake City, UT 84132
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Bio

Dr.Ramkumar is an Assistant Professor at the University of Utah School of Medicine. She received her medical degree from Bangalore University, India and obtained her Master's degree in Public Health from the University of Utah. She completed her residency training in Internal Medicine at UCSF-Fresno and Nephrology fellowship training at University of Utah. Her clinical interests include hypertension, polycystic kidney disease and glomerulonephritis. She oversees Nephrology fellows in training in the outpatient and inpatient settings.

Board Certification and Academic Information

Academic Departments Internal Medicine - Assistant Professor
Academic Divisions Nephrology
Board Certification American Board of Internal Medicine
American Board of Internal Medicine (Sub: Nephrology)

Academic Profile

Research Interests

  • Hypertension
  • Ion Transport
  • Diabetes Mellitus, Experimental
  • Progression of Chronic Kidney Disease

Board Certification and Academic Information

Academic Departments Internal Medicine - Assistant Professor
Academic Divisions Nephrology
Board Certification American Board of Internal Medicine
American Board of Internal Medicine (Sub: Nephrology)

Academic Office Locations

Academic Office Phone Number Academic Office Address
(801) 581-6709 School of Medicine
Division of Nephrology & Hypertension
30 N 1900 E
Salt Lake City, UT 84132

Academic Bio

Dr.Ramkumar is an Assistant Professor at the University of Utah School of Medicine. She received her medical degree from Bangalore University, India and obtained her Master's degree in Public Health from the University of Utah. She completed her residency training in Internal Medicine at UCSF-Fresno and Nephrology fellowship training at University of Utah. Her clinical interests include hypertension, polycystic kidney disease and glomerulonephritis. She oversees Nephrology fellows in training in the outpatient and inpatient settings.

Research Statement

My research is focused on understanding the role of the intra-renal renin angiotensin system in health and disease. Using cell-specific gene targeting, our laboratory has developed mouse models that lack and/or overexpress components of the renin angiotensin system within the kidney. We have demonstrated that nephron derived angiotensinogen, renin and the prorenin receptor play an important role in sodium reabsoprtion and blood pressure regulation during hypertensive states. Our long term goal is to understand the pathophysiological mechanisms that contribute to the development of hypertension and kidney disease.

Education

Education History

Type School Degree
Fellowship University of Utah
Nephrology
Fellow
Residency UCSF-Fresno
Internal Medicine
Resident
Internship UCSF-Fresno
Family Medicine
Intern
Graduate Training University of Utah
Public Health
M.P.H.
Professional Medical Bangalore University
Medicine
M.B.B.S.

Publications

Selected Provider Publications

Journal Article

  1. Song K, Stuart D, Abraham N, Wang F, Wang S, Yang T, Sigmund CD, Kohan DE, Ramkumar N (2016). Collecting duct renin does not mediate DOCA-Salt hypertension or renal Injury. PLoS ONE, 11(7), e0159872.
  2. Ramkumar N, Stuart D, Mirinova E, Bugay V, Wang S, Abraham N, Ichihara A, Stockand JD, Kohan DE (2016). Renal tubular epithelial cell prorenin receptor regulates blood pressure and sodium transport. Am J Physiol Renal Physiol, 311, F186-F194.
  3. Ramkumar N, Stuart D, Calquin M, Wang S, Niimura F, Matsusaka T, Kohan DE 2016 1 (1/28/2016). Possible role for nephron-derived angiotensinogen in angiotensin-II dependent hypertension. Physiol Rep, 4(1).
  4. Ramkumar N, Stuart D, Calquin M, Quadri S, Wang S, Van Hoek AN, Siragy HM, Ichihara A, Kohan DE (2015). Nephron specific deletion of the prorenin receptor causes a urine concentration defect. Am J Physiol Renal Physiol, 309:F48-F56.
  5. Ramkumar N, Stuart D, Rees S, Van Hoek A, Sigmund CD, Kohan DE (2014). Collecting duct specific knock-out renin attenuates angiotensin-II induced hypertension. Am J Physiol Renal Physiol, 307: F931-938.
  6. Ramkumar N, Ying J, Stuart D, Kohan DE (2013). Overexpression of renin in the collecting duct causes elevated blood pressure. Am J Hypertens, 26(8), 965-72.
  7. Ramkumar N, Stuart D, Ying J, Kohan DE (2013). Evidence for an interaction between systemic and renal angiotensinogen in the control of blood pressure. Am J Hypertens, 26(4), 473-480.
  8. Roos KP, Bugaj V, Mironova E, Stockand JD, Ramkumar N, Rees S, Kohan DE (2013). Adenylyl Cyclase VI Mediates Vasopressin-Stimulated ENaC Activity. J Am Soc Nephrol, 24(2), 218-27.
  9. Ying J, Stuart D, Hillas E, Gociman BR, Ramkumar N, Lalouel JM, Kohan DE (2012). Overexpression of mouse angiotensinogen in renal proximal tubule causes salt-sensitive hypertension in mice. Am J Hypertens, 25(6), 684-9.
  10. Ramkumar N, Murtaugh MA, Cheung AK, Beddhu S (2007). Lack of synergistic effects of metabolic syndrome and plasma fibrinogen on coronary events and mortality in moderate CKD. Am J Kidney Dis, 49(3), 356-64.
  11. Hawkes CH, Ramkumar N, Baker R, Lyon JL (2007). Multiple sclerosis in Latter Day Saints (Mormons). Acta Neurol Scand, 115(4), 260-4.
  12. Logar CM, Pappas LM, Ramkumar N, Beddhu S (2005). Surgical revascularization versus amputation for peripheral vascular disease in dialysis patients: a cohort study. BMC Nephrol, 6, 3.
  13. Morris D, Samore MH, Pappas LM, Ramkumar N, Beddhu S (2005). Nutrition and racial differences in cardiovascular events and survival in elderly dialysis patients. Am J Med, 118(6), 671-5.
  14. Ramkumar N, Pappas LM, Beddhu S (2005). Effect of body size and body composition on survival in peritoneal dialysis patients. Perit Dial Int, 25(5), 461-9.
  15. Beddhu S, Kimmel PL, Ramkumar N, Cheung AK (2005). Associations of metabolic syndrome with inflammation in CKD: results From the Third National Health and Nutrition Examination Survey (NHANES III). Am J Kidney Dis, 46(4), 577-86.
  16. Ramkumar N, Beddhu S, Eggers P, Pappas LM, Cheung AK (2005). Patient preferences for in-center intense hemodialysis. Hemodial Int, 9(3), 281-95.
  17. Beddhu S, Ramkumar N, Pappas LM (2005). Normalization of protein intake by body weight and the associations of protein intake with nutritional status and survival. J Ren Nutr, 15(4), 387-97.
  18. Beddhu S, Pappas LM, Ramkumar N, Samore MH (2004). Malnutrition and atherosclerosis in dialysis patients. J Am Soc Nephrol, 15(3), 733-42.
  19. Ramkumar N, Cheung AK, Pappas LM, Roberts WL, Beddhu S (2004). Association of obesity with inflammation in chronic kidney disease: a cross-sectional study. J Ren Nutr, 14(4), 201-7.
  20. Beddhu S, Samore MH, Roberts MS, Stoddard GJ, Ramkumar N, Pappas LM, Cheung AK (2003). Impact of timing of initiation of dialysis on mortality. J Am Soc Nephrol, 14(9), 2305-12.
  21. Beddhu S, Pappas LM, Ramkumar N, Samore M (2003). Effects of body size and body composition on survival in hemodialysis patients. J Am Soc Nephrol, 14(9), 2366-72.

Review

  1. Ramkumar N, Kohan DE (2016). The nephron prorenin receptor: function and significance. [Review]. American Journal of Physiology. Renal Physiology, 311(6), F1145-1148.
  2. Ramkumar N, Kohan DE (2016). Role of the collecting duct renin angiotensin system in regulation of blood pressure and renal function. [Review]. Current Hypertension Reports, 18(4), 29.
  3. Ramkumar N, Kohan DE (2013). Role of collecting duct renin in blood pressure regulation. [Review]. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, 305(2), R92-94.
  4. Ramkumar N, Kohan DE (2013). Proximal tubule angiotensinogen modulation of arterial pressure. [Review]. Current Opinion in Nephrology & Hypertension, 22(1), 32-6.

Global Impact

Global Impact

Education History

Type School Degree Country
Professional Medical Bangalore University
Medicine
M.B.B.S. India

Clinical Trials

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