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Julio Delgado, M.D., M.S.

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Specialties

  • Pathology, Clinical

Languages

  • English
  • Spanish

Clinical Details

Schedule An Appointment Clinical Office Address
(801) 583-2787 ARUP
500 Chipeta Way
Salt Lake City, UT 84108

Specialties

  • Pathology, Clinical

Bio

Dr. Delgado is the group medical director of the Immunology Division and co-executive director of the Institute for Clinical and Experimental Pathology at ARUP, as well as director of the Histocompatibility and Immnogenetics laboratory at University of Utah hospital. He is an associate professor of pathology at the University of Utah School of Medicine. He is board certified in clinical pathology and histocompatibility laboratory testing by the American Board of Pathology and the American Board of Histocompatibility and Immunogenetics.

Board Certification and Academic Information

Academic Departments Pathology - Associate Professor
Academic Divisions Clinical Pathology
Board Certification American Board of Histocompatibility
American Board of Pathology (Clinical Path)

Academic Profile

Research Interests

  • Epitopes, T-Lymphocyte
  • Transplantation Immunology
  • Immunogenetics
  • Proteomics
  • Immunogenicity of Biologics
  • Histocompatibility Testing
  • Post-Transplant Monitoring

Board Certification and Academic Information

Academic Departments Pathology - Associate Professor
Academic Divisions Clinical Pathology
Board Certification American Board of Histocompatibility
American Board of Pathology (Clinical Path)

Academic Bio

Dr. Delgado received his MD from Universidad Industrial de Santander in Colombia and his MS degree in epidemiology from the Harvard School of Public Health, completing both his clinical residency training in clinical pathology and his research fellowship in immunology and immunogenetics at the Harvard Medical School.

Education

Education History

Type School Degree
Graduate Training Harvard School of Public Health
Epidemiology
M.S.
Postdoctoral Training CBR Institute for Biomedical Research
Immunology Research
Postdoctoral Training
Fellowship Harvard Medical School
Pathology
Fellow
Chief Resident Brigham and Women's Hospital
Pathology
Chief Resident
Postdoctoral Fellowship Dana-Farber Cancer Institute
Immunogenetics
Postdoctoral Fellow
Professional Medical Universidad Industrial de Santander
Medicine
M.D.

Publications

Selected Provider Publications

Journal Article

  1. Vonderheid EC, Pavlov I, Delgado JC, Martins TB, Telang GH, Hess AD, Kadin ME (2014). Prognostic factors and risk stratification in early mycosis fungoides. Leuk Lymphoma, 55(1), 44-50.
  2. Chen L, Reyes-Vargas E, Dai H, Escobar H, Rudd B, Fairbanks J, Ho A, Cusick MF, Kumanovics A, Delgado J, He X, Jensen PE (2014). Expression of the mouse MHC class Ib H2-T11 gene product, a paralog of H2-T23 (Qa-1) with shared peptide-binding specificity. J Immunol, 193(3), 1427-39.
  3. Heikal NM, Bader FM, Martins TB, Pavlov IY, Wilson AR, Barakat M, Stehlik J, Kfoury AG, Gilbert EM, Delgado JC, Hill HR (2013). Immune function surveillance: association with rejection, infection and cardiac allograft vasculopathy. Transplant Proc, 45(1), 376-82.
  4. Cronin K, Escobar H, Szekeres K, Reyes-Vargas E, Rockwood AL, Lloyd MC, Delgado JC, Blanck G (2013). Regulation of HLA-DR peptide occupancy by histone deacetylase inhibitors. Hum Vaccin Immunother, 9(4), 784-9.
  5. Kanaseki T, Lind KC, Escobar H, Nagarajan N, Reyes-Vargas E, Rudd B, Rockwood AL, Van Kaer L, Sato N, Delgado JC, Shastri N (2013). ERAAP and tapasin independently edit the amino and carboxyl termini of MHC class I peptides. J Immunol, 191(4), 1547-55.
  6. Ravkov EV, Pavlov IY, Martins TB, Gleich GJ, Wagner LA, Hill HR, Delgado JC (2013). Identification and validation of shrimp-tropomyosin specific CD4 T cell epitopes. Hum Immunol, 74(12), 1542-9.
  7. Kadin ME, Pavlov IY, Delgado JC, Vonderheid EC (2012). High soluble CD30, CD25, and IL-6 may identify patients with worse survival in CD30+ cutaneous lymphomas and early mycosis fungoides. J Invest Dermatol, 132(3 Pt 1), 703-10.
  8. Kincaid EZ, Che JW, York I, Escobar H, Reyes-Vargas E, Delgado JC, Welsh RM, Karow ML, Murphy AJ, Valenzuela DM, Yancopoulos GD, Rock KL (2012). Mice completely lacking immunoproteasomes show major changes in antigen presentation. Nat Immunol, 13(2), 129-35.
  9. Taborda NA, Catano JC, Delgado JC, Rugeles MT, Montoya CJ (2012). Higher SLPI expression, lower immune activation, and increased frequency of immune cells in a cohort of Colombian HIV-1 controllers. J Acquir Immune Defic Syndr, 60(1), 12-9.
  10. Wang S, Delgado JC, Ravkov E, Eckels DD, Georgelas A, Pavlov IY, Cusick M, Sebastian K, Gleich GJ, Wagner LA (2012). Penaeus monodon tropomyosin induces CD4 T-cell proliferation in shrimp-allergic patients. Hum Immunol, 73(4), 426-31.
  11. Cho HI, Reyes-Vargas E, Delgado JC, Celis E (2012). A potent vaccination strategy that circumvents lymphodepletion for effective antitumor adoptive T-cell therapy. Cancer Res, 72(8), 1986-95.
  12. Escobar H, Reyes-Vargas E, Jensen PE, Delgado JC, Crockett DK (2011). Utility of characteristic QTOF MS/MS fragmentation for MHC class I peptides. J Proteome Res, 10(5), 2494-507.
  13. Profaizer T, Eckels D, Delgado JC (2011). Celiac disease and HLA typing using real-time PCR with melting curve analysis. Tissue Antigens, 78(1), 31-7.
  14. Blanchard N, Kanaseki T, Escobar H, Delebecque F, Nagarajan NA, Reyes-Vargas E, Crockett DK, Raulet DH, Delgado JC, Shastri N (2010). Endoplasmic reticulum aminopeptidase associated with antigen processing defines the composition and structure of MHC class I peptide repertoire in normal and virus-infected cells. J Immunol, 184(6), 3033-42.
  15. Delgado JC, Escobar H, Crockett DK, Reyes-Vargas E, Jensen PE (2009). Identification of naturally processed ligands in the C57BL/6 mouse using large-scale mass spectrometric peptide sequencing and bioinformatics prediction. Immunogenetics, 61(3), 241-6.
  16. Delgado JC, Fuller A, Ozawa M, Smith L, Terasaki PI, Shihab FS, Eckels DD (2009). No occurrence of de novo HLA antibodies in patients with early corticosteroid withdrawal in a 5-year prospective randomized study. Transplantation, 87(4), 546-8.
  17. Chen LC, Delgado JC, Jensen PE, Chen X (2009). Direct expansion of human allospecific FoxP3+CD4+ regulatory T cells with allogeneic B cells for therapeutic application. J Immunol, 183(6), 4094-102.
  18. Stehlik J, Islam N, Hurst D, Kfoury AG, Movsesian MA, Fuller A, Delgado JC, Hammond ME, Gilbert EM, Renlund DG, Bader F, Fisher PW, Bull DA, Singhal AK, Eckels DD (2009). Utility of virtual crossmatch in sensitized patients awaiting heart transplantation. J Heart Lung Transplant, 28(11), 1129-34.
  19. Delgado JC, Pavlov IY, Shihan FS (2009). Post-transplant increased levels of serum sCD30 is a marker for prediction of kidney allograft loss in a 5-year prospective study. Transpl Immunol, 22(1-2), 1-4.
  20. Bedoya VI, Jaimes FA, Delgado JC, Rugeles C, Usuga X, Zapata W, Castano ME, Boasso A, Shearer G, Rugeles MT (2008). Fetal-maternal HLA-A and -B discordance is associated with placental RNase expression and anti-HIV-1 activity. Curr HIV Res, 6(4), 380-7.
  21. Escobar H, Crockett DK, Reyes-Vargas E, Baena A, Rockwood AL, Jensen PE, Delgado JC (2008). Large scale mass spectrometric profiling of peptides eluted from HLA molecules reveals N-terminal-extended peptide motifs. J Immunol, 181(7), 4874-82.
  22. Delgado JC, Baena A, Thim S, Goldfeld AE (2006). Aspartic acid homozygosity at codon 57 of HLA-DQ beta is associated with susceptibility to pulmonary tuberculosis in Cambodia. J Immunol, 176(2), 1090-7.
  23. Husain Z, Almeciga I, Delgado JC, Clavijo OP, Castro JE, Belalcazar V, Pinto C, Zuniga J, Romero V, Yunis EJ (2006). Increased FasL expression correlates with apoptotic changes in granulocytes cultured with oxidized clozapine. Toxicol Appl Pharmacol, 214(3), 326-34.
  24. Thim S, Sath S, Sina M, Tsai EY, Delgado JC, Shapiro AE, Barry CE 3rd, Glaziou P, Goldfeld AE (2004). A community-based tuberculosis program in Cambodia. JAMA, 292(5), 566-8.
  25. Delgado JC, Quinones-Berrocal J, Thim S, Miranda LF, Goldfeld AE (2004). Diagnostic and clinical implications of response to tuberculin in two ethnically distinct populations from Peru and Cambodia. Int J Tuberc Lung Dis, 8(8), 982-7.
  26. Delgado JC, Leung JY, Baena A, Clavijo OP, Vittinghoff E, Buchbinder S, Wolinsky S, Addo M, Walker BD, Yunis EJ, Goldfeld AE (2003). The -1030/-862-linked TNF promoter single-nucleotide polymorphisms are associated with the inability to control HIV-1 viremia. Immunogenetics, 55(7), 497-501.
  27. Delgado JC, Tsai EY, Thim S, Baena A, Boussiotis VA, Reynes JM, Sath S, Grosjean P, Yunis EJ, Goldfeld AE (2002). Antigen-specific and persistent tuberculin anergy in a cohort of pulmonary tuberculosis patients from rural Cambodia. Proc Natl Acad Sci U S A, 99(11), 7576-81.
  28. Delgado JC, Baena A, Thim S, Goldfeld AE (2002). Ethnic-specific genetic associations with pulmonary tuberculosis. J Infect Dis, 186(10), 1463-8.
  29. Baena A, Leung JY, Sullivan AD, Landires I, Vasquez-Luna N, Quinones-Berrocal J, Fraser PA, Uko GP, Delgado JC, Clavijo OP, Thim S, Meshnick SR, Nyirenda T, Yunis EJ, Goldfeld AE (2002). TNF-alpha promoter single nucleotide polymorphisms are markers of human ancestry. Genes Immun, 3(8), 482-7.
  30. Flores-Villanueva PO, Yunis EJ, Delgado JC, Vittinghoff E, Buchbinder S, Leung JY, Uglialoro AM, Clavijo OP, Rosenberg ES, Kalams SA, Braun JD, Boswell SL, Walker BD, Goldfeld AE (2001). Control of HIV-1 viremia and protection from AIDS are associated with HLA-Bw4 homozygosity. Proc Natl Acad Sci U S A, 98(9), 5140-5.
  31. Delgado JC, Greene MF, Winkelman JW, Tanasijevic MJ (2000). Comparison of disaturated phosphatidylcholine and fetal lung maturity surfactant/albumin ratio in diabetic and nondiabetic pregnancies. Am J Clin Pathol, 113(2), 233-9.
  32. Boussiotis VA, Tsai EY, Yunis EJ, Thim S, Delgado JC, Dascher CC, Berezovskaya A, Rousset D, Reynes JM, Goldfeld AE (2000). IL-10-producing T cells suppress immune responses in anergic tuberculosis patients. J Clin Invest, 105(9), 1317-25.
  33. Clavijo OP, Delgado JC, Yu N, Fraser PA, Yunis EJ (1999). HLA-Cw*1701 is associated with two sub-Saharan African-derived HLA haplotypes: HLA-B*4201, DRB1*03 and HLA-B*4202 without DRB1*03. Tissue Antigens, 54(3), 303-6.
  34. Goldfeld AE, Delgado JC, Thim S, Bozon MV, Uglialoro AM, Turbay D, Cohen C, Yunis EJ (1998). Association of an HLA-DQ allele with clinical tuberculosis. JAMA, 279(3), 226-8.
  35. Weinreb S, Delgado JC, Clavijo OP, Yunis EJ, Bayer-Zwirello L, Polansky L, Deluhery L, Cohn G, Yao JT, Stec TC, Higby D, Anderzejewski C (1998). Transplantation of unrelated cord blood cells. Bone Marrow Transplant, 22(2), 193-6.
  36. Clavijo OP, Delgado JC, Awdeh ZL, Fici D, Turbay D, Alper CA, Truedsson L, Yunis EJ (1998). HLA-Cw alleles associated with HLA extended haplotypes and C2 deficiency. Tissue Antigens, 52(3), 282-5.
  37. Uglialoro AM, Turbay D, Pesavento PA, Delgado JC, McKenzie FE, Gribben JG, Hartl D, Yunis EJ, Goldfeld AE (1998). Identification of three new single nucleotide polymorphisms in the human tumor necrosis factor-alpha gene promoter. Tissue Antigens, 52(4), 359-67.
  38. Turbay D, Lieberman J, Alper CA, Delgado JC, Corzo D, Yunis JJ, Yunis EJ (1997). Tumor necrosis factor constellation polymorphism and clozapine-induced agranulocytosis in two different ethnic groups. Blood, 89(11), 4167-74.
  39. Bozon MV, Delgado JC, Selvakumar A, Clavijo OP, Salazar M, Ohashi M, Alosco SM, Russell J, Yu N, Dupont B, Yunis EJ (1997). Error rate for HLA-B antigen assignment by serology: implications for proficiency testing and utilization of DNA-based typing methods. Tissue Antigens, 50(4), 387-94.
  40. Schultze JL, Michalak S, Seamon MJ, Dranoff G, Jung K, Daley J, Delgado JC, Gribben JG, Nadler LM (1997). CD40-activated human B cells: an alternative source of highly efficient antigen presenting cells to generate autologous antigen-specific T cells for adoptive immunotherapy. J Clin Invest, 100(11), 2757-65.
  41. Mobini N, Yunis EJ, Alper CA, Yunis JJ, Delgado JC, Yunis DE, Firooz A, Dowlati Y, Bahar K, Gregersen PK, Ahmed AR (1997). Identical MHC markers in non-Jewish Iranian and Ashkenazi Jewish patients with pemphigus vulgaris: possible common central Asian ancestral origin. Hum Immunol, 57(1), 62-7.
  42. Delgado JC, Hameed A, Yunis JJ, Bhol K, Rojas AI, Rehman SB, Khan AA, Ahmad M, Alper CA, Ahmed AR, Yunis EJ (1997). Pemphigus vulgaris autoantibody response is linked to HLA-DQB1*0503 in Pakistani patients. Hum Immunol, 57(2), 110-9.
  43. Delgado JC, Turbay D, Yunis EJ, Yunis JJ, Morton ED, Bhol K, Norman R, Alper CA, Good RA, Ahmed R (1996). A common major histocompatibility complex class II allele HLA-DQB1* 0301 is present in clinical variants of pemphigoid. Proc Natl Acad Sci U S A, 93(16), 8569-71.
  44. Bozon MV, Delgado JC, Turbay D, Salazar M, Granja CB, Alosco SM, Dupont B, Yunis EJ (1996). Comparison of HLA-A antigen typing by serology with two polymerase chain reaction based DNA typing methods: implications for proficiency testing. Tissue Antigens, 47(6), 512-8.
  45. Delgado JC, Yunis DE, Bozon MV, Salazar M, Deulofeut R, Turbay D, Mehra NK, Pasricha JS, Raval RS, Patel H, Shah BK, Bhol K, Alper CA, Ahmed AR, Yunis EJ (1996). MHC class II alleles and haplotypes in patients with pemphigus vulgaris from India. Tissue Antigens, 48(6), 668-72.

Review

  1. Delgado JC, Eckels DD (2008). Positive B-cell only flow cytometric crossmatch: implications for renal transplantation. [Review]. Exp Mol Pathol, 85(1), 59-63.

Commentary

  1. Delgado JC, Jensen PE (2008). Cat and mouse. Nat Immunol, 9(8), 829-30.
  2. Delgado JC, Jensen PE (2007). Trimming creates a new self-image. Nat Immunol, 8(1), 21-2.

Clinical Trials

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