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Amnon Schlegel, M.D., Ph.D.

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Specialties

Languages

  • English

Clinical Details

Schedule An Appointment Clinical Office Address
(801) 581-7763 Utah Diabetes Center
615 Arapeen Drive, Suite 100
Salt Lake City, UT 84108

Bio

At the Utah Diabetes and Endocrinology Center and the George E. Wahlen Department of Veterans Affairs Medical Center, Dr. Schlegel sees patients with all general endocrine and metabolic disorders. He has particular interest in disorders of lipid metabolism.

Board Certification and Academic Information

Academic Departments Internal Medicine - Assistant Professor
Biochemistry - Adjunct Assistant Professor
Academic Divisions Endocrinology and Metabolism
Board Certification American Board of Internal Medicine (Internal Medicine)
American Board of Internal Medicine (Sub: Endocrinology, Diabetes & Metabolism)

Academic Profile

Research Interests

  • Diabetes Mellitus
  • Non-alcoholic Fatty Liver Disease
  • Obesity
  • Kinase
  • Zebrafish
  • Adipose Tissue
  • Ketone Bodies
  • Endocrinology
  • Hormones
  • Monocarboxylate Transporter
  • Biochemistry
  • Lipids
  • Molecular Genetics

Board Certification and Academic Information

Academic Departments Internal Medicine - Assistant Professor
Biochemistry - Adjunct Assistant Professor
Academic Divisions Endocrinology and Metabolism
Board Certification American Board of Internal Medicine (Internal Medicine)
American Board of Internal Medicine (Sub: Endocrinology, Diabetes & Metabolism)

Academic Office Locations

Academic Office Phone Number Academic Office Address
(801) 585-0730 George and Dolores Eccles Institute of Human Genetics
15 N 2030 E
Salt Lake City, UT 84112

Academic Bio

Dr. Schlegel was a trainee in the Medical Scientist Training Program of the Albert Einstein College of Medicine where he received his M.D. and Ph.D. He was an intern and resident physician at Beth Israel Deaconess Medical Center in Boston, MA, and was a Fellow in Medicine at Harvard Medical School. He was a clinical fellow in the Diabetes, Endocrine, and Metabolism Training Program at the University of California San Francisco, where he was subsequently a post-doctoral associate in the laboratory of Professor Didier Y.R. Stainier, Ph.D., in the Department of Biochemistry and Biophysics. It was there that he established a zebrafish molecular genetic system for studying lipid metabolism.

In 2010, Dr. Schlegel was recruited to the University of Utah as an investigator in the Molecular Medicine Program and as an Assistant Professor of Internal Medicine and Biochemistry. He hosts graduate students in his lab through the Biochemistry and Molecular Biology Graduate programs. His laboratory uses model organisms (zebrafish and mice) to identify and characterize new genes that participate in lipid metabolism. The long-term goal of this work is to identify novel therapeutic targets for treating obesity, type 2 diabetes, and lipid disorders.

Dr. Schlegel is heavily involved in undergraduate and graduate medical education, lecturing second year medical students on lipid disorders and endocrine hypertension; delivering noon conferences to the Internal Medicine house staff on the same topics; serving as a General Medicine ward attending physician (annual fortnight) at the George E. Wahlen Department of Veterans Affairs Medical Center; performing one month annualy of in-patient Endocrinology consultations; and staffing a weekly fellows' clinic at the Utah Diabetes and Endocrinology Center and a General Endocrinology clinic at the George E. Wahlen Department of Veterans Affairs Medical Center. He is a regular discussant at Internal Medicine resident conferences.

Education

Education History

Type School Degree
Fellowship University of California, San Francisco
Diabetes, Endocrinology and Metabolism
Fellow
Residency Beth Israel Deaconess Medical Center
Internal Medicine
Resident
Internship Beth Israel Deaconess Medical Center
Internal Medicine
Intern
Professional Medical Albert Einstein College of Medicine
Medicine
M.D.
Doctoral Training Albert Einstein College of Medicine
Medical Scientist Training Program, Department of Molecular Pharmacology
Ph.D.
Undergraduate Hofstra University
Biochemistry
B.S.

Publications

Selected Provider Publications

Journal Article

  1. Cruz-Garcia L, Schlegel A (2014). Lxr-driven enterocyte lipid droplet formation delays transport of ingested lipids. J Lipid Res, 55(9), 1944-58.
  2. Karanth S, Tran VM, Kuberan B, Schlegel A (2013). Polyunsaturated fatty acyl-Coenzyme As are inhibitors of cholesterol biosynthesis in zebrafish and mice. Dis Model Mech, 6(6), 1365-77.
  3. Hugo SE, Cruz-Garcia L, Karanth S, Anderson RM, Stainier DYR, Schlegel A (2012). A monocarboxylate transporter required for hepatocyte secretion of ketone bodies during fasting. Genes Dev, 26(3), 282-293.

Review

  1. Schlegel, A (2012). Studying nonalcoholic fatty liver disease with zebrafish-- a confluence of optics, genetics, and physiology. [Review]. Cellular and Molecular Life Sciences, 69(23), 3965-3961.
  2. Schlegel A, Stainier DY (2007). Lessons from "lower" organisms: what worms, flies, and zebrafish can teach us about human energy metabolism. [Review]. PLoS Genet, 3(11), e199.

Clinical Trials

Video & News