Succinylcholine injection

What is succinylcholine injection?

SUCCINYLCHOLINE (Anectine®) is a muscle relaxant. It relaxes muscles during surgery or before investigational procedures. Generic succinylcholine injections are available.

What should my health care professional know before I receive succinylcholine?

They need to know if you have any of these conditions:

  • anemia

  • dehydration

  • fever

  • glaucoma

  • heart disease

  • hypothermia or hyperthermia (changes in normal body temperature)

  • infection

  • kidney disease

  • liver disease

  • malnutrition

  • muscle weakness or disease

  • serious burns or other injuries

  • an unusual or allergic reaction to succinylcholine, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should I use this medicine?

Succinylcholine is for injection into a vein, or infusion into a vein. It is given by a health-care professional in a hospital or clinic setting.

What if I miss a dose?

This does not apply.

What drug(s) may interact with succinylcholine?

  • acetazolamide

  • beta blockers, often used for high blood pressure or heart problems

  • capreomycin

  • certain antibiotics given by injection

  • cyclophosphamide

  • doxapram

  • echothiophate

  • female hormones, including contraceptive or birth control pills

  • heart medicine such as digoxin

  • lithium

  • magnesium salts

  • medicines for mental problems and psychotic disturbances

  • medicines for pain

  • medicines that relax your muscles during surgery

  • medicines to control heart rhythm

  • neostigmin

  • pilocarpine

  • procaine

  • thiotepa

  • trimethaphan

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What should I watch for while taking succinylcholine?

You will be carefully monitored for side effects while you receive succinylcholine, and for some time afterwards.

What side effects may I notice from receiving succinylcholine?

Side effects that you should report to your prescriber or health care professional as soon as possible:

  • eye pain

  • fainting or lightheadedness

  • fever

  • increased heartbeat

  • irregular heartbeat

  • rapid breathing

  • reduced amount of urine passed

  • rigid muscles, especially the jaw muscles

  • shortness of breath, wheezing

  • trembling

Call your prescriber or health care professional for advice if you get any of these side effects.

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

  • flushing (reddening of skin)

  • muscle pain

  • increased saliva

Where can I keep my medicine?

Keep out of reach of children.

Store the ready prepared injection in a refrigerator between 2 and 8 degrees C (36 and 46 degrees F). Do not freeze. Do not use unless the solution is clear. Store the sterile powder for injection between 15 and 30 degrees C (59 and 86 degrees F). Once powder is dissolved use within 24 hours, Throw away any unused portion.