Typhoid Fever

What is typhoid fever?

Typhoid fever is a life-threatening infection caused by bacteria. It is common in the rest of the world, but not in the U.S. Most cases in this country are in people who got the disease while traveling elsewhere.

You can get the disease by eating food or drinking water that is contaminated with the bacteria.

What causes typhoid fever?

Typhoid fever is caused by bacteria (S. typhi). The bacteria are passed on by eating food or drinking water that has been touched by someone with the disease. The bacteria are also found in the infected person’s stool. You can also get the disease if water used for drinking or washing food is contaminated with sewage containing the bacteria.

People who recover from typhoid fever still carry the bacteria and can pass them on to other people.

What are the symptoms of typhoid fever?

Once the bacteria are in your body, they increase in number and spread into your blood. You may not have symptoms for 6 to 30 days after the first exposure. Symptoms may include:

  • Fever of 102°F to 104°F (39°C to 40°C)
  • Weakness
  • Stomach pains
  • Headache
  • Loss of appetite
  • Sometimes a rash of flat, rose-colored spots

The symptoms may look like other health problems. Always see your health care provider for a diagnosis.

How is typhoid fever diagnosed?

Your health care provider will use a blood test or stool sample to diagnose typhoid fever. These tests can find the typhoid bacteria. But these tests are less accurate if you have just come down with the disease. Because of this, your provider will also look at your symptoms and travel history.

How is typhoid fever treated?

See your health care provider right away if you think you have been exposed to typhoid fever. People who are not treated may have a fever for weeks or months. They may eventually die from complications.

Antibiotics are often used to treat typhoid fever. But your health care provider will figure out the best treatment for you based on:

  • How old you are
  • Your overall health and past health
  • How sick you are
  • How well you can handle specific medicines, procedures, or therapies
  • How long the condition is expected to last
  • Your opinion or preference

It is important to remember that the danger of typhoid fever does not end when symptoms go away. You could still be carrying the bacteria. The illness could also return. Or you could pass the disease to other people. You should:

  • Take any antibiotics exactly as your health care provider tells you to.
  • Always wash your hands after using the bathroom.
  • Have a series of stool cultures. This is to make sure that the bacteria are no longer in your body.

What are the complications of typhoid fever?

Complications of typhoid fever include intestinal bleeding and a hole in the intestine. Either of these can be fatal if not treated right away.

Once your symptoms are gone, you may still have the typhoid bacteria in your body. Follow up with your health care provider to make sure the bacteria are completely gone. You will also need to practice good hygiene. Wash your hands before and after you use the bathroom. You should also not make food for anyone else until the bacteria are gone.

Can typhoid fever be prevented?

Typhoid fever is very common in developing countries. Travelers to Africa, Latin America, and Asian countries except Japan are at highest risk. A vaccine is available. It should be taken 1 to 2 weeks before traveling. But it can lose effectiveness after several years. So you may need a booster shot.

You can also prevent typhoid when traveling by only using water that has been boiled or chemically disinfected. Use this water for:

  • Drinking or making beverages, such as tea or coffee
  • Brushing teeth
  • Washing your face and hands. You can also use an alcohol-based gel to wash your hands.
  • Washing fruits and vegetables
  • Washing eating utensils, pots, and pans
  • Washing the surfaces of tins, cans, and bottles that contain food or beverages

Also do not eat food from street vendors. Any raw food could be contaminated. Avoid:

  • Fruits and vegetables, particularly those that cannot be peeled 
  • Salad greens 
  • Unpasteurized milk and milk products
  • Raw meat
  • Shellfish
  • Any fish caught in tropical reefs rather than the open ocean

Other tips for prevention:

  • Do not eat food or drink beverages from unknown sources.
  • Do not put ice in drinks.


When should I call my health care provider?

Call your health care provider right way if your symptoms return or get worse, or you have new ones.

Key points

  • Typhoid fever is a life-threatening infection caused by bacteria.
  • In the U.S., most cases are in people who get the disease while traveling abroad.
  • Symptoms include a high fever, weakness, stomach pains, headache, and loss of appetite. Sometimes, a rash of flat, rose-colored spots may appear.
  • Antibiotics are often used to treat the disease.
  • To prevent typhoid fever, drink only boiled or chemically disinfected water. Also do not eat raw food that could be contaminated.

Next steps

Tips to help you get the most from a visit to your health care provider:

  • Before your visit, write down questions you want answered.
  • Bring someone with you to help you ask questions and remember what your provider tells you.
  • At the visit, write down the names of new medicines, treatments, or tests, and any new instructions your provider gives you.
  • If you have a follow-up appointment, write down the date, time, and purpose for that visit.
  • Know how you can contact your provider if you have questions.