Hodgkin's Lymphoma

Adult Hodgkin's lymphoma is a type of cancer that develops in the lymph system, part of the body's immune system.

The lymph system is made up of the following:

  • Lymph: Colorless, watery fluid that travels through the lymph system and carries white blood cells called lymphocytes. Lymphocytes protect the body against infections and the growth of tumors.
  • Lymph vessels: A network of thin tubes that collect lymph from different parts of the body and return it to the bloodstream.
  • Lymph nodes: Small, bean-shaped structures that filter lymph and store white blood cells that help fight infection and disease. Lymph nodes are located along the network of lymph vessels found throughout the body. Clusters of lymph nodes are found in the underarm, pelvis, neck, abdomen, and groin.
  • Spleen: An organ that makes lymphocytes, filters the blood, stores blood cells, and destroys old blood cells. It is located on the left side of the abdomen near the stomach.
  • Thymus: An organ in which lymphocytes grow and multiply. The thymus is in the chest behind the breastbone.
  • Tonsils: Two small masses of lymph tissue at the back of the throat. The tonsils make lymphocytes.
  • Bone marrow: The soft, spongy tissue in the center of large bones. Bone marrow makes white blood cells, red blood cells, and platelets.

Because lymph tissue is found throughout the body, Hodgkin's lymphoma can begin in almost any part of the body and spread to almost any tissue or organ in the body.

Hodgkin's lymphoma can occur in both adults and children; however, treatment for adults may be different than treatment for children. Hodgkin lymphoma may also occur in patients who have acquired immunodeficiency syndrome (AIDS); these patients require special treatment. Hodgkin's lymphoma in pregnant women is the same as the disease in nonpregnant women of childbearing age. However, treatment is different for pregnant women. This summary includes information about treating Hodgkin lymphoma during pregnancy.

There are two main types of Hodgkin's lymphoma: classical and nodular lymphocyte-predominant. Most Hodgkin's lymphomas are the classical type. The classical type is broken down into the following four subtypes:

  • Nodular sclerosing Hodgkin's lymphoma.
  • Mixed cellularity Hodgkin's lymphoma.
  • Lymphocyte depletion Hodgkin's lymphoma.
  • Lymphocyte-rich classical Hodgkin's lymphoma.

Risk Factors
Symptoms
Screening and Diagnosis
Staging
Treatment
Support

ctt line break

Risk Factors

Anything that increases your risk of getting a disease is called a risk factor. Having a risk factor does not mean that you will get cancer; not having risk factors doesn't mean that you will not get cancer. Talk with your doctor if you think you may be at risk. Risk factors for adult Hodgkin's lymphoma include the following:

  • Being in young or late adulthood
  • Being male
  • Being infected with the Epstein-Barr virus
  • Having a first-degree relative (parent, brother, or sister) with Hodgkin lymphoma

Pregnancy is not a risk factor for Hodgkin's lymphoma.

Top

ctt line break

Symptoms

Signs of adult Hodgkin's lymphoma include swollen lymph nodes, fever, night sweats, and weight loss. These and other signs and symptoms may be caused by adult Hodgkin lymphoma or by other conditions. Check with your doctor if any of the following do not go away:

  • Painless, swollen lymph nodes in the neck, underarm, or groin
  • Fever for no known reason
  • Drenching night sweats
  • Weight loss for no known reason
  • Itchy skin
  • Feeling very tired

Top

ctt line break

Screening and Diagnosis

Tests that examine the lymph nodes are used to detect (find) and diagnose adult Hodgkin's lymphoma. The following tests and procedures may be used:

  • Physical exam and history: An exam of the body to check general signs of health, including checking for signs of disease, such as lumps or anything else that seems unusual. A history of the patient's past illnesses and treatments will also be taken.
  • Complete blood count (CBC): A procedure in which a sample of blood is drawn and checked for the following:
    • The number of red blood cells, white blood cells, and platelets.
    • The amount of hemoglobin (the protein that carries oxygen) in the red blood cells.
    • The portion of the sample made up of red blood cells.
  • Blood chemistry studies: A procedure in which a blood sample is checked to measure the amounts of certain substances released into the blood by organs and tissues in the body. An unusual (higher or lower than normal) amount of a substance can be a sign of disease in the organ or tissue that makes it.
  • Sedimentation rate: A procedure in which a sample of blood is drawn and checked for the rate at which the red blood cells settle to the bottom of the test tube.
  • Lymph node biopsy: The removal of all or part of a lymph node. One of the following types of biopsies may be done:
  • Excisional biopsy: The removal of an entire lymph node.
  • Incisional biopsy: The removal of part of a lymph node.
  • Core biopsy: The removal of part of a lymph node using a wide needle.

A pathologist views the tissue under a microscope to look for cancer cells, especially Reed-Sternberg cells. Reed-Sternberg cells are common in classical Hodgkin's lymphoma.

The following test may be done on tissue that was removed:

  • Immunophenotyping: A laboratory test used to identify cells, based on the types of antigens or markers on the surface of the cell. This test is used to diagnose the specific type of lymphoma by comparing the cancer cells to normal cells of the immune system.

Top

ctt line break

Staging

After adult Hodgkin lymphoma has been diagnosed, tests are done to find out if cancer cells have spread within the lymph system or to other parts of the body.

The process used to find out if cancer has spread within the lymph system or to other parts of the body is called staging. The information gathered from the staging process determines the stage of the disease. It is important to know the stage in order to plan treatment. The following tests and procedures may be used in the staging process:

  • CT scan (CAT scan): A procedure that makes a series of detailed pictures of areas inside the body, taken from different angles. The pictures are made by a computer linked to an x-ray machine. A dye may be injected into a vein or swallowed to help the organs or tissues show up more clearly. This procedure is also called computed tomography, computerized tomography, or computerized axial tomography. For adult Hodgkin's lymphoma, CT scans of the neck, chest, abdomen, and pelvis are taken.
  • PET-CT scan: A procedure that combines the pictures from a positron emission tomography (PET) scan and a computed tomography (CT) scan. The PET and CT scans are done at the same time on the same machine. The pictures from both scans are combined to make a more detailed picture than either test would make by itself. A PET scan is a procedure to find malignant tumor cells in the body. A small amount of radioactive glucose (sugar) is injected into a vein. The PET scanner rotates around the body and makes a picture of where glucose is being used in the body. Malignant tumor cells show up brighter in the picture because they are more active and take up more glucose than normal cells do.
  • Bone marrow aspiration and biopsy: The removal of bone marrow, blood, and a small piece of bone by inserting a hollow needle into the hipbone or breastbone. A pathologist views the bone marrow, blood, and bone under a microscope to look for signs of cancer.

For pregnant women with Hodgkin lymphoma, staging tests that protect the fetus from the harms of radiation are used. These include:

  • MRI (magnetic resonance imaging): A procedure that uses a magnet, radio waves, and a computer to make a series of detailed pictures of areas inside the body. This procedure is also called nuclear magnetic resonance imaging (NMRI).
  • Ultrasound exam: A procedure in which high-energy sound waves (ultrasound) are bounced off internal tissues or organs and make echoes. The echoes form a picture of body tissues called a sonogram.

There are three ways that cancer spreads in the body.

Cancer can spread through tissue, the lymph system, and the blood:

  • Tissue. The cancer spreads from where it began by growing into nearby areas.
  • Lymph system. The cancer spreads from where it began by getting into the lymph system. The cancer travels through the lymph vessels to other parts of the body.
  • Blood. The cancer spreads from where it began by getting into the blood. The cancer travels through the blood vessels to other parts of the body.

Stages of adult Hodgkin's lymphoma may include A, B, E, and S as follows:

  • A: The patient does not have B symptoms (fever, weight loss, or night sweats).
  • B: The patient has B symptoms.
  • E: Cancer is found in an organ or tissue that is not part of the lymph system but which may be next to an involved area of the lymph system.
  • S: Cancer is found in the spleen.

The following stages are used for adult Hodgkin's lymphoma:

Stage I

Stage I is divided into stage I and stage IE.

  • Stage I: Cancer is found in one of the following places in the lymph system:
    • One or more lymph nodes in one lymph node group.
    • Waldeyer's ring.
    • Thymus.
    • Spleen.
  • Stage IE: Cancer is found outside the lymph system in one organ or area.

Stage II

Stage II is divided into stage II and stage IIE.

  • Stage II: Cancer is found in two or more lymph node groups either above or below the diaphragm (the thin muscle below the lungs that helps breathing and separates the chest from the abdomen).
  • Stage IIE: Cancer is found in one or more lymph node groups either above or below the diaphragm and outside the lymph nodes in a nearby organ or area.

Stage III

Stage III is divided into stage III, stage IIIE, stage IIIS, and stage IIIE,S.

  • Stage III: Cancer is found in lymph node groups above and below the diaphragm (the thin muscle below the lungs that helps breathing and separates the chest from the abdomen).
  • Stage IIIE: Cancer is found in lymph node groups above and below the diaphragm and outside the lymph nodes in a nearby organ or area.
  • Stage IIIS: Cancer is found in lymph node groups above and below the diaphragm, and in the spleen.
  • Stage IIIE,S: Cancer is found in lymph node groups above and below the diaphragm, outside the lymph nodes in a nearby organ or area, and in the spleen.

Stage IV

In stage IV, the cancer:

  • is found outside the lymph nodes throughout one or more organs, and may be in lymph nodes near those organs; or
  • is found outside the lymph nodes in one organ and has spread to areas far away from that organ; or
  • is found in the lung, liver, bone marrow, or cerebrospinal fluid (CSF). The cancer has not spread to the lung, liver, bone marrow, or CSF from nearby areas.

Adult Hodgkin's lymphoma may be grouped for treatment as follows:

Early Favorable - Early favorable adult Hodgkin's lymphoma is stage I or stage II, without risk factors.

Early Unfavorable - Early unfavorable adult Hodgkin's lymphoma's is stage I or stage II with one or more of the following risk factors:

  • A tumor in the chest that is larger than 1/3 of the width of the chest or at least 10 centimeters.
  • Cancer in an organ other than the lymph nodes.
  • A high sedimentation rate (in a sample of blood, the red blood cells settle to the bottom of the test tube more quickly than normal).
  • Three or more lymph nodes with cancer.
  • Symptoms such as fever, weight loss, or night sweats.

Advanced Favorable - Advanced favorable adult Hodgkin's lymphoma is stage III or stage IV with three or fewer of the following risk factors:

  • Being male.
  • Being aged 45 years or older.
  • Having stage IV disease.
  • Having a low blood albumin (protein) level (below 4).
  • Having a low hemoglobin level (below 10.5).
  • Having a high white blood cell count (15,000 or higher).
  • Having a low lymphocyte count (below 600 or less than 8% of the white blood cell count).

Advanced Unfavorable - Advanced unfavorable Hodgkin's lymphoma is stage III or stage IV with four or more of the following risk factors:

  • Being male.
  • Being aged 45 years or older.
  • Having stage IV disease.
  • Having a low blood albumin (protein) level (below 4).
  • Having a low hemoglobin level (below 10.5).
  • Having a high white blood cell count (15,000 or higher).
  • Having a low lymphocyte count (below 600 or less than 8% of the white blood cell count).

Top

ctt line break

Treatment

At Huntsman Cancer Institute, Hodgkin's lymphoma is treated by a team of specialists, including hematologists (doctors who specialize in treating blood disorders), medical oncologists (doctors who treat cancer with medicine), radiation oncologists (doctors who treat cancer with radiation), nurses, dietitians, and social workers.

Three standard treatments are used:

New treatments are being studied in clinical trials.

Different types of treatment are available for patients with adult Hodgkin's lymphoma. Some treatments are standard (the currently used treatment), and some are being tested in clinical trials. A treatment clinical trial is a research study meant to help improve current treatments or obtain information on new treatments for patients with cancer. When clinical trials show that a new treatment is better than the standard treatment, the new treatment may become the standard treatment. Patients may want to think about taking part in a clinical trial. Some clinical trials are open only to patients who have not started treatment.

For pregnant women with Hodgkin's lymphoma, treatment is carefully chosen to protect the fetus. Treatment decisions are based on the mother’s wishes, the stage of the Hodgkin lymphoma, and the age of the fetus. The treatment plan may change as the signs and symptoms, cancer, and pregnancy change. Choosing the most appropriate cancer treatment is a decision that ideally involves the patient, family, and health care team.

Patients with Hodgkin's lymphoma should have their treatment planned by a team of health care providers with expertise in treating lymphomas.

Treatment will be overseen by a medical oncologist, a doctor who specializes in treating cancer. The medical oncologist may refer you to other health care providers who have experience and expertise in treating adult Hodgkin lymphoma and who specialize in certain areas of medicine. These may include the following specialists:

  • Neurosurgeon
  • Neurologist
  • Rehabilitation specialist
  • Radiation oncologist
  • Endocrinologist
  • Hematologist
  • Other oncology specialists

Patients may develop late effects that appear months or years after their treatment for Hodgkin's lymphoma.

Treatment with chemotherapy and/or radiation therapy for Hodgkin's lymphoma may increase the risk of second cancers and other health problems for many months or years after treatment. These late effects depend on the type of treatment and the patient's age when treated, and may include:

  • Acute myelogenous leukemia
  • Cancer of the breast, bone, cervix, gastrointestinal tract, head and neck, lung, soft tissue, and thyroid
  • Heart, lung, and thyroid disease
  • Avascular necrosis of bone (death of bone cells caused by lack of blood flow)
  • Herpes zoster (shingles) or severe infection
  • Depression and fatigue
  • Infertility
  • Hypogonadism (low levels of testosterone and estrogen).

Regular follow-up by doctors who are expert in finding and treating late effects is important for the long-term health of patients treated for Hodgkin's lymphoma.

Chemotherapy

Chemotherapy is a cancer treatment that uses drugs to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. When chemotherapy is taken by mouth or injected into a vein or muscle, the drugs enter the bloodstream and can reach cancer cells throughout the body (systemic chemotherapy). When chemotherapy is placed directly into the cerebrospinal fluid, an organ, or a body cavity such as the abdomen, the drugs mainly affect cancer cells in those areas (regional chemotherapy). The way the chemotherapy is given depends on the type and stage of the cancer being treated. Combination chemotherapy is treatment with more than one anticancer drug.

When a pregnant woman is treated with chemotherapy for Hodgkin lymphoma, it isn't possible to protect the fetus from being exposed to the chemotherapy. Some chemotherapy regimens may cause birth defects if given in the first trimester. Vinblastine is an anticancer drug that has not been linked with birth defects when given in the second half of pregnancy.

Learn more about this treatment in our introduction to chemotherapy video.

 

Radiation therapy

Radiation therapy is a cancer treatment that uses high-energy x-rays or other types of radiation to kill cancer cells or keep them from growing. There are two types of radiation therapy. External radiation therapy uses a machine outside the body to send radiation toward the cancer. Internal radiation therapy uses a radioactive substance sealed in needles, seeds, wires, or catheters that are placed directly into or near the cancer. The way the radiation therapy is given depends on the type and stage of the cancer being treated.

For a pregnant woman with Hodgkin's lymphoma, radiation therapy should be postponed until after delivery, if possible, to avoid any risk to the fetus. If immediate treatment is needed, the woman may decide to continue the pregnancy and receive radiation therapy. However, lead used to shield the fetus may not protect it from scattered radiation that could possibly cause cancer in the future.

Surgery

Laparotomy is a procedure in which an incision (cut) is made in the wall of the abdomen to check the inside of the abdomen for signs of disease. The size of the incision depends on the reason the laparotomy is being done. Sometimes organs are removed or tissue samples are taken and checked under a microscope for signs of disease. If cancer is found, the tissue or organ is removed during the laparotomy.

For pregnant patients with Hodgkin's lymphoma, treatment options also include:

  • Watchful waiting: Watchful waiting is closely monitoring a patient’s condition without giving any treatment unless signs or symptoms appear or change. Delivery may be induced when the fetus is 32 to 36 weeks old, so that the mother can begin treatment.
  • Steroid therapy: Steroids are hormones made naturally in the body by the adrenal glands and by reproductive organs. Some types of steroids are made in a laboratory. Certain steroid drugs have been found to help chemotherapy work better and help stop the growth of cancer cells. Steroids can also help the lungs of the fetus develop faster than normal. This is important when delivery is induced early.

Clinical trials

This section describes treatments that are being studied in clinical trials. It may not mention every new treatment being studied. For more information, visit HCI's clinical trials website.

  • Chemotherapy and radiation therapy with stem cell transplant: High-dose chemotherapy and radiation therapy with stem cell transplant is a way of giving high doses of chemotherapy and radiation therapy and replacing blood-forming cells destroyed by the cancer treatment. Stem cells (immature blood cells) are removed from the blood or bone marrow of the patient or a donor and are frozen and stored. After therapy is completed, the stored stem cells are thawed and given back to the patient through an infusion. These reinfused stem cells grow into (and restore) the body's blood cells. The use of lower-dose chemotherapy and radiation therapy with stem cell transplant is also being studied.
  • Monoclonal antibody therapy: Monoclonal antibody therapy is a cancer treatment that uses antibodies made in the laboratory, from a single type of immune system cell. These antibodies can identify substances on cancer cells or normal substances that may help cancer cells grow. The antibodies attach to the substances and kill the cancer cells, block their growth, or keep them from spreading. Monoclonal antibodies are given by infusion. They may be used alone or to carry drugs, toxins, or radioactive material directly to cancer cells.

Top

ctt line break

Support

When you or someone you love is diagnosed with cancer, concerns about treatments and side effects, hospital stays, and medical bills are common. You may also worry about caring for your family, work, or normal daily life.

There are several places you can go for support:

  • Your health care team can answer your questions and talk to you about your concerns. They can help you with any side effects and keep you informed of all your treatments, test results, and future doctor visits.
  • The G. Mitchell Morris Cancer Learning Center has hundreds of free brochures and more than 3,000 books, DVDs, and CDs available for checkout. You can browse the library, perform Internet research, or talk with a cancer information specialist.
  • Our Patient and Family Support Services offer emotional support and resources for coping with cancer and its impact on daily life to HCI patients and their families.
  • The Linda B. and Robert B. Wiggins Wellness-Survivorship Center offers many programs to increase the quality of life and well-being of HCI patients and their families.

Top

ctt line break

 

Adapted from the National Cancer Institute's Physician Data Query (PDQ®) Cancer Information Summaries
This information last updated on HCI website January 2014

*If you are interested in a trial that is currently marked *Not Open, please contact the Patient Education team at 1-888-424-2100 or patient.education@hci.utah.edu for other trial options. Enrollment is updated daily.

Forte Research Systems in partnership with Huntsman Cancer Institute

Djordje Atanackovic, M.D.

Specialties: Amyloidosis, Cancer Immunotherapy, Hematology/BMT, Myeloma, Plasma Cell Leukemia, Plasmacytoma, Tumor Immunology

Michael W. Boyer, M.D.

Locations
Huntsman Cancer Hospital (801) 585-2626
Primary Children's Hospital (801) 662-4700

Specialties: Blood and Marrow Transplantation, Hematology/BMT, Pediatric Hematology & Oncology, Stem Cell Transplant

Amie Clark, APRN, FNP

Locations
Huntsman Cancer Hospital (801) 587-4630
Huntsman Cancer Hospital (801) 585-6906

Specialties: Family Nurse Practitioner, Hematology/BMT, Oncology

Michael W. Deininger, M.D., Ph.D.

Locations
Huntsman Cancer Hospital (801) 585-6906
Huntsman Cancer Hospital (801) 587-4630

Specialties: Chronic Myeloid Leukemia, Hematology/BMT, Leukemia, Myeloproliferative Neoplasms

Andrew C. Dietz, M.D., M.S.

Specialties: Blood and Marrow Transplantation, Pediatric Hematology & Oncology

David K. Gaffney, M.D., Ph.D.

Locations
Huntsman Cancer Hospital (801) 581-2396

Specialties: Breast Cancer, Gynecologic Oncology, Lymphomas, Radiation Oncology

Martha J. Glenn, M.D.

Locations
Huntsman Cancer Hospital (801) 585-6906
Huntsman Cancer Hospital (801) 585-0100

Specialties: Chronic Lymphocytic Leukemia, Hematology/BMT, Hodgkin Lymphoma, Leukemia, Lymphomas, Lymphoproliferative Diseases, Non-Hodgkin Lymphoma, Oncology

Ahmad Halwani, M.D.

Locations
Huntsman Cancer Hospital (801) 585-2626

Specialties: Hematology/BMT, Medical Oncology

Teresa Herlevi, PA-C

Locations
Huntsman Cancer Hospital (801) 585-0303

Specialties: Hematology/BMT, Physician Assistant

Gerhard Carl Hildebrandt, M.D., FACP

Locations
Huntsman Cancer Hospital (801) 585-6906

Specialties: Amyloidosis, Aplastic Anemia, Hematology/BMT, Immunotherapy, Leukemia, Lymphomas, Multiple Myeloma, Myeloma

Tibor Kovacsovics, M.D.

Locations
Huntsman Cancer Hospital (801) 585-2626
Huntsman Cancer Hospital (801) 585-2626

Specialties: Hematology/BMT

Amanda A. Langemo, M.P.A.S.

Locations
Huntsman Cancer Hospital (801) 587-4477

Specialties: Hematology/BMT, Physician Assistant

Brenda S. Mueggenborg, APRN

Locations
University Hospital (801) 585-3229

Specialties: Hematology/BMT, Nurse Practitioner

Danielle Nance, M.D.

Specialties: Hematology/BMT

J. Dane Osborn, M.D.

Specialties: Hematology/BMT

Charles J. Parker, M.D.

Locations
Huntsman Cancer Hospital (801) 585-3229
Veterans Administration Medical Center (801) 584-1272

Specialties: Hematology/BMT, Hemochromatosis, Paroxysmal Nocturnal Hemoglobinuria, Porphyria

Esteban Peña, M.D.

Specialties: Hematology/BMT

Josef T. Prchal, M.D.

Locations
Huntsman Cancer Hospital (801) 585-6906
Veterans Administration Medical Center (801) 582-1565

Specialties: Anemia, Hematology/BMT, Myeloproliferative Disorders, Oncology, Thrombocythemia

Michael Allen Pulsipher, B.A., M.D.

Locations
Huntsman Cancer Hospital (801) 585-0100
Primary Children's Hospital (801) 662-4830
Primary Children's Hospital (801) 662-4700

Specialties: Benign Hematology, Blood and Marrow Transplantation, Brain Tumors, Hematology/BMT, Leukemia, Lymphomas, Neuroblastoma, Pediatric Hematology & Oncology

George M. Rodgers, III, M.D., Ph.D.

Locations
Huntsman Cancer Hospital (801) 585-2626

Specialties: Benign Hematology, Coagulation, Hematology/BMT, Hereditary Hemorrhagic Telangiectasia

Andrea M. Schindler, APRN

Locations
Huntsman Cancer Hospital (801) 585-6906

Specialties: Hematology/BMT, Nurse Practitioner

Jaime Shahan, PA-C

Locations
Huntsman Cancer Hospital (801) 585-2626

Specialties: Hematology/BMT, Physician Assistant

Paul J. Shami, M.D.

Locations
Huntsman Cancer Hospital (801) 585-0100

Specialties: Hematology/BMT, Leukemia, Myelodysplasia, Oncology

Mary Steinbach, M.S.N., APRN

Locations
Huntsman Cancer Hospital (801) 587-4474

Specialties: Family Nurse Practitioner, Hematology/BMT

John Sweetenham, M.D., FACP, FRCP

Locations
Huntsman Cancer Hospital (801) 585-6906

Specialties: Hematology/BMT, Lymphomas

Jonathan D. Tward, M.D., Ph.D.

Locations
Huntsman Cancer Hospital (801) 581-2396
South Jordan Health Center (801) 213-4320

Specialties: Bladder Cancer, Brachytherapy, Gastrointestinal Cancers, Genitourinary Cancers, Intensity-Modulated Radiation Therapy (IMRT), Lymphomas, Penile Cancer, Prostate Cancer, Radiation Oncology, Robotic Prostatectomy, Seed Implants, Stereotactic Body Radiation Therapy (SBRT), Urologic Oncology

Renee A. Vadeboncoeur, M.S.N., APRN

Locations
Huntsman Cancer Hospital (801) 585-0100

Specialties: Family Nurse Practitioner, Hematology/BMT

HCI Resources

Make An Appointment

Lauren PitcherHematology Cancer Program
Care coordinator: Lauren Pitcher
Phone: 801-585-6906
E-mail: lauren.pitcher@hci.utah.edu

Did You Know?

  • Hodgkin's lymphoma is most common among teens, also adults under age 35 and those over age 55.
  • Adult Hodgkin's lymphoma can usually be cured if found and treated early.
  • Huntsman Cancer Institute (HCI) refers children with Hodgkin's lymphoma to Primary Children's Hospital. This facility is recognized as one of the top children's hospitals in the United States and is located on the same medical campus as HCI, allowing our specialists to collaborate in the treatment and management of childhood cancers.
clc graphic right column