Cancer Control and Population Sciences

CCPS Membership Directory

cancer control population sciences research program

The Cancer Control and Population Sciences (CCPS) Program is a comprehensive basic and applied research program that spans the cancer control continuum from etiology, primary prevention, screening, and early detection to continuing care, survivorship, and end-of-life care. The unifying long-range goals of the program are to prevent cancer and reduce cancer morbidity and mortality.

The work of the CCPS Program is organized around two central scientific themes 1) Translational Cancer Predisposition Genetics and 2) Cancer Behavioral and Outcomes Research, which are pursued using the following approaches:

Translational Cancer Predisposition Genetics (Theme 1)

  • Studies of cancer familiality, both to inform gene discovery efforts and to inform genetic counseling of patients and their potentially at-risk relatives.
  • Cancer susceptibility, gene discovery, and evaluation, emphasizing high-risk and intermediate-risk susceptibility genes and analysis of rare sequence variants (including variants of unknown significance).

Program Reports

2015 Report

CCPS Program Newsletters

CCPS 2014 Summer Newsletter

Previous newsletters are available upon request
.

Cancer Behavioral and Outcomes Research (Theme 2)

  • Identifying and testing strategies to ameliorate cancer disparities in the Cancer Center catchment area with a focus on Native American and Latino communities and disparities based on geography, including rural and frontier communities.
  • Identifying, testing, and translating strategies to improve outcomes including cancer diagnostic, treatment, symptom, supportive care, family caregiver, survivor, and other quality-of-life outcomes.

Influence of Genetics on Behavior and Outcomes (intersection of Theme 1 and 2)

  • Improving risk communication, risk reduction, and surveillance in members of intermediate-risk and high-risk families through studies of attitudes and preferences towards genetic risk testing, effective communication of risk information, and behavioral, medical, and/or surgical interventions and outcomes.
  • Risk predictions through studies of environmental and gene-environmental epidemiology, including creative use of the unique population science resource, the Utah Population Database, as well as participation in, and leadership of, large national and international epidemiology consortia.

Program scientific discoveries and accomplishments include creation of a national resource linking genealogy to phenotype data, identification of two breast cancer susceptibility genes, demonstration of an interaction between smoking and alcohol consumption that can cause markedly elevated risk of upper aerodigestive tract cancers, and understanding cancer disparities in vulnerable populations within the catchment area.

The CCPS Program is co-led by Kathleen Mooney, PhD, RN, and Sean Tavtigian, PhD, who bring together members with a broad range of expertise including basic laboratory, epidemiological, socio-behavioral, clinical research on cancer risk factors and mechanisms, and intervention trial design and execution, under the shared belief that the maximal value of fundamental or basic discoveries is achieved only when research is translated into evidence-based clinical and public health strategies.

The Cancer Control and Population Sciences Program received $10.6 million in total research support from the National Institutes of Health, the American Cancer Society, the National Science Foundation, and other funding agencies in 2013, with 78% coming from the National Cancer Institute. Cancer-focused articles published between 2009-2013 total 525, of which 14% are inter-programmatic and 29% are intra-programmatic publications.

Sean V. Tavtigian, PhD
Co-Leader

Kathleen Mooney, PhD
Co-Leader

sean tavtigian kathleen mooney
                                

CCPS Membership Directory

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Name E-mail Research Interests Website
Alter, OrlyOrly Alter e-mail Matrix and tensor modeling of large-scale molecular biological data which can be used to correctly predict previously unknown physical, cellular, and evolutionary mechanisms that govern the activity of DNA and RNA.
Aspinwall, LisaLisa Aspinwall e-mail Psychological and behavioral response to genetic testing for mutations that increase cancer risk.  
Beck, SusanSusan Beck e-mail

Pain and symptom management; quality of life; cancer survivorship.

Boucher, KennethKenneth Boucher e-mail Cancer biostatistics website
Brown, BarbaraBarbara Brown e-mail

Healthy levels of physical activity that might reduce trends toward overweight and risk of cancer.

Buys, Saundrasaundra buys e-mail Breast cancer genetics, cancer screening.
Camp, NicolaNicola Camp e-mail

Localizing genes for complex traits including increased cancer risks; evaluating genotype/phenotype relationship; developing statistical genetic methods.

Cannon-Albright, LisaLisa Cannon-Albright e-mail

Breast cancer susceptibility gene identification; disease predisposition genes with an emphasis on melanoma and prostate cancer.

Caserta, MichaelMichael Caserta e-mail How aspects of cancer caregiving influences health and well-being outcomes; intervening relationship with self-care practices.
Clayton, Margaretmargaret clayton e-mail

Cancer communications with breast cancer survivors.

Contreras, JorgeJorge Contreras e-mail

Gene patenting, particularly the Myriad Genetics case involving the patenting of the BRCA 1/2 breast/ovarian cancer genes and alleles.

Cooney, KathleenLee Ellington e-mail

Furthering the ability to identify genetic defects in sporadic and hereditary prostate cancer.

Curtin, KarenKaren Curtin e-mail Genetic and epigenetic risk factors for cancer and their relationship to environmental influences.
Doherty, JenniferLee Ellington e-mail

Molecular and genetic patho-epidemiology of ovarian and lung cancers

Donaldson, GaryLee Ellington e-mail

Substantive and methodological integration in the fields of acute and chronic pain, cancer, and quality of life in progressive disease

Ellington, LeeLee Ellington e-mail Patient-provider communication psycho- oncology.
Fagerlin, AngelaLee Ellington e-mail

Methods to improve shared decision making regarding cancer screening and cancer treatment between patients and their physicians

Fluchel, MarkMark Fluchel e-mail Oncology trials in pediatric patients
Goldgar, Daviddavid goldgar e-mail

Genetic studies of breast cancer and melanoma; clinical classification of BRCA1 and BRCA2.

Hanson, HeidiHeidi Hanson e-mail Promote healthy aging and longevity by understanding genetic and environmental determinants of health throughout the life course.
Hashibe, MiaMia Hashibe e-mail Global and molecular epidemiology of cancer website
Henry, NorahLee Ellington e-mail Translational research in breast oncology, and predictors of both response to and toxicity of therapy.
Hess, Rachelrachel-hess.jpg e-mail Implementation science and Health-related quality of life and its response to life transitions.
Hu, NanNan Hu e-mail Statistical methodology in diagnostic/ prognostic study in clinical trials in survival analysis and their application to cancer diagnosis and screening.
Jensen, JakobJakob Jensen e-mail Cancer communication; psychometric of key cancer constructs and the design and behavioral interventions. website
Kaphingst, KimberlyLee Ellington e-mail Communicating genetic and genomic information related to cancer risk.
Kepka, Deanna L.Deanna Kepka e-mail Cervical cancer prevention and control; specifically HPV vaccination; prevention of cancer-related disparities among vulnerable populations.
Kirchhoff, AnneAnne Kirchhoff e-mail Assessing how cancer affects social and economic outcomes for childhood cancer survivors. website
LaStayo, PaulPaul LaStayo e-mail Aging cancer patients and survivors
Leachman, SancySancy Leachman e-mail Melanoma genetics translation website
Lee, CatherineCatherine Lee e-mail The evaluation of the expression and function of T cell immunoglobulin and mucin domain-3 (TIM-3), a candidate biomarker of acute myeloid leukemia stem cells.
Lee, YoungheeLee Ellington e-mail Dynamic genetic and epigenetic regulations of alternative splicing patterns across diverse cancer cell types (Pan-Cancer), and cancer-specific driver transcripts and regulators.
Lee, Yuan-Chin (Amy)Yuan Chin (Amy) Lee e-mail Utilize etiological information; identify interventions; perform controlled trials; establish sustainable interventions in the population to improve cancer prevention measures and quality of life for cancer patients.
Linder, LauriLauri Linder e-mail Symptom management for children and adolescents with an emphasis on the use of technology to support symptom assessment and interventions.

Lopez, Ana MariaLee Ellington

e-mail Collaborative research to inform access to care with a focus on integrative oncology.
Lowrance, WilliamWilliam Lowrance e-mail Surgical treatment for urologic malignancies
Marth, GaborMarth Gabor e-mail Computational biology; genomic variant identification and interpretation.
Monroe, MarcusMarcus Monroe e-mail Survivorship in head and neck and thyroid cancer; thyroid cancer risk stratification; HPV, head and neck cancers.
Mooney, KathleenKathleen Mooney e-mail Quality of life, prevention adherence behaviors, cancer symptom experience
Neklason, DeborahDeborah Neklason e-mail Genetic etiology of colon cancer website
Ozanne, Elissaelissa-ozanne.jpg e-mail Implementation and evaluation of decision support for patients and providers, and cost-effectiveness evaluation of interventions.
Rothwell, ErinErin Rothwell e-mail Cancer support groups and biobehavioral models for improving quality of life for individuals diagnosed with cancer
Rupper, RandallRandall Rupper e-mail Cancer screening, diagnosis, and treatment decisions of older adults
Samadder, JewelJewel Samadder e-mail Gastrointestinal cancer syndromes; endoscopic oncology
Samowitz, WadeWade Samowitz e-mail Colorectal cancer genetics
Slattery, Marty L.Lee Ellington e-mail Epidemiological methods, environmental and genetic factors affecting cancer development
Smith, KenKen Smith e-mail Psychosocial consequences of genetic testing
Sweeney, CarolCarol Sweeney e-mail Molecular epidemiology of cancer
Tavtigian, Sean V.Sean Tavtigian e-mail Identification and characterization of intermediate -risk and high-risk cancer susceptibility genes, primarily breast, ovarian and prostate. website
Ulrich, CorneliaCornelia Ulrich e-mail Colorectal cancer, exercise and cancer website
Wen, MingLee Ellington e-mail Socio-environmental influences on health, including cancer.
Wetter, DavidLee Ellington e-mail Eliminating inequities in health-related behavior through translational research.
Wu, YelenaYelena Wu e-mail Identifying the psychological and behavioral factors impacting health self-management within pediatric oncology populations, and designing interventions to improve self- management and health outcomes. website
Yandell, MarkMark Yandell e-mail

Development of computational genomics tools for personalized medicine, cancer, infectious disease, population biology, agriculture, and forensics.

website

Top