Knowledge of the genetic basis of cancer is essential to understanding the disease. Genetic data is important in all aspects of cancer management, including the following:
Cancer susceptibility genes
In some families, DNA tests can identify specific gene mutations as the cause of inherited cancer risk and determine whether family members have inherited the disease-related mutation. Genetic test results are unclear when an unclassified variant (a change in the DNA with unknown significance) is found. Research continues at Huntsman Cancer Institute to learn more about these variants and their significance. Learn more about cancer susceptibility or view our cancer topic about Genetics and Cancer.