Ken Boucher Group

Publications

Biostatistics and Computational Biology

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A model of multiple tumorigenesis allowing for cell death: quantitative insight into biological effects of urethane.
Boucher K,
Pavlova LV, Yakovlev AY (1998).
Math BioSci, 150(1), 63-82.

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Measures of familial aggregation as predictors of breast-cancer risk.
Boucher KM,
Kerber RA (2001).
J Epidemiol Biostat, 6(5), 377-85.

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Estimating an oncogenetic tree when false negatives and positives are present.
Szabo A, Boucher K (2002).
Math BioSci, 176(2), 219-36.

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Empirical methods for controlling false positives and estimating confidence in ChIP-Seq peaks.
Nix DA, Courdy SJ, Boucher KM (2008).
BMC Bioinformatics, 9(1), 523.

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The Balanced Survivor Average Causal Effect.
Greene T, Joffe M, Hu B, Li L, Boucher K (2013).
Int J Biostat, 1-16.

Clinical Trials

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First-in-human mutation-targeted siRNA phase Ib trial of an inherited skin disorder.
Leachman SA, Hickerson RP, Schwartz ME, Bullough EE, Hutcherson SL, Boucher KM, Hansen CD, Eliason MJ, Srivatsa GS, Kornbrust DJ, Smith FJ, McLean WI, Milstone LM, Kaspar RL (2010).
Mol Ther, 18(2), 442-6.

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A phase II study of bevacizumab and erlotinib as initial treatment for metastatic non-squamous, non-small cell lung cancer with serum proteomic evaluation.
Akerley W, Boucher K, Rich N, Egbert L, Harker G, Bylund J, Van Duren T, Reddy C (2013).
Lung Cancer, 79(3), 307-11.

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Telehealth Personalized Cancer Risk Communication to Motivate Colonoscopy in Relatives of Patients With Colorectal Cancer: The Family CARE Randomized Controlled Trial.
Kinney AY, Boonyasiriwat W, Walters ST, Pappas LM, Stroup AM, Schwartz MD, Edwards SL, Rogers A, Kohlmann WK, Boucher KM, Vernon SW, Simmons RG, Lowery JT, Flores K, Wiggins CL, Hill DA, Burt RW, Williams MS, Higginbotham JC (2014).
J Clin Oncol, 32(7), 654-62.

Laboratory Sciences

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GSTM4 is a microsatellite-containing EWS/FLI target involved in Ewing's sarcoma oncogenesis and therapeutic resistance.
Luo W, Gangwal K, Sankar S, Boucher KM, Thomas D, Lessnick SL (2009).
Oncogene, 28(46), 4126-32.

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Trans-centromere effects on meiotic recombination in the zebrafish.
Demarest BL, Horsley WH, Locke EE, Boucher K, Grunwald DJ, Trede NS (2011).
Genetics, 187(1), 333-6.

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TRIM29 functions as a tumor suppressor in nontumorigenic breast cells and invasive ER+ breast cancer.
Liu J, Welm B, Boucher KM, Ebbert MT, Bernard PS (2012).
Am J Pathol, 180(2), 839-47.

Population Sciences

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American founder mutation for attenuated familial adenomatous polyposis.
Neklason DW, Stevens J, Boucher KM, Kerber RA, Matsunami N, Barlow J, Mineau G, Leppert MF, Burt RW (2008).
Clin Gastroenterol Hepatol, 6(1), 46-52.

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Oncogenetic tree model of somatic mutations and DNA methylation in colon tumors.
Sweeney C, Boucher KM, Samowitz WS, Wolff RK, Albertsen H, Curtin K, Caan BJ, Slattery ML (2009).
Genes Chromosomes Cancer, 48(1), 1-9.

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A genome-wide study replicates linkage of 3p22-24 to extreme longevity in humans and identifies possible additional loci.
Kerber RA, O'Brien E, Boucher KM, Smith KR, Cawthon RM (2012).
PLoS ONE, 7(4), e34746.

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A population-based study of childhood cancer survivors' body mass index.
Warner EL, Fluchel M, Wright J, Sweeney C, Boucher KM, Fraser A, Smith KR, Stroup AM, Kinney AY, Kirchhoff AC (2014).
J Cancer Epidemiol, 2014, 531958.