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Sequenom Clinical Research

Squenom

The Molecular Diagnostics laboratory utilizes the Sequenom MassArray for SNP genotyping and somatic mutation profiling of clinical trial specimens. A pipeline has been developed to obtain specimens from consented patients, isolate DNA, perform sequencing, and generate a report within 1-2 weeks.

The Molecular Diagnostics Staff will work with clinical researchers to develop custom SNP genotyping or Somatic Mutation panels utilizing the Sequenom MassArray.  The main advantage of this technology is the ability to go from DNA to data in one day, which makes it well suited for clinical research.  After a new panel has been developed, initial validation studies are performed to determine the sensitivity, reproducibility and lower level of detection of the assay.  Upon completion of the initial validation studies, the Molecular Diagnostics laboratory will perform analysis of clinical trial specimens in real time.

Sequencing data generated by the Molecular Diagnostics Laboratory are for research purposes only. The results are NOT CLIA certified and cannot be used for standard of care treatment decisions.

If you are interested in utilizing the Sequenom MassArray in your clinical trial, please contact the Molecular Diagnostics Staff.