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Fluorescence Microscopy

Director
Christopher Rodesch, PhD
crodesch@cores.utah.edu
801-587-7964

The Fluorescence Microscopy (FM) Shared Resource provides a broad range of microscopy services for Huntsman Cancer Institute (HCI) members and the entire University of Utah research community. The primary focus of the Resource is to provide state-of-the-art instrumentation, software, and expertise necessary for imaging live and fixed cells. The facility has two Olympus FV1000 spectral confocal microscopes, two FV300 confocals, an FVX 2Photon confocal, a Pathway 855 high-throughput confocal, a Yokagowa spinning disk confocal for low-light live cell imaging, and two widefield microscopes equipped with digital cameras. Computational support for 3D rendering, quantification, and deconvolution of images (e.g., Volocity from Improvision, Imaris from Bitplane) is also provided. The FM Resource provides training in the use of current techniques and equipment by direct assistance and through formal University courses.

The FM Shared Resource serves members of the HCI laboratory-based scientific Programs (Nuclear Control of Cell Growth and Differentiation, Cell Response and Regulation, and Experimental Therapeutics), enabling them to visualize cell morphology and behavior as well as distribution of molecules into cellular compartments in both normal and diseased states. The FM Shared Resource enhances studies of gene expression, apoptosis, and cell division. It allows characterization of tumor growth and morphology.

For more information, please see the Fluorescence Microscopy webpage on the University of Utah HSC Core Facility website: http://cellimagin1.web117.discountasp.net/website/index.html.

Fluorescence Microscopy Governance

Director
Chris Rodesch, PhD

HCI Senior Director Oversight
David Jones, PhD

Faculty Advisory Committee Members
Donald Ayer, PhD
Chi-Bin Chien, PhD
Wesley Sundquist, PhD

If use of this resource results in a publication, please acknowledge the Cancer Center Support Grant by using the following text: "The project described was supported by Award Number P30CA042014 from the National Cancer Institute. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Cancer Institute or the National Institutes of Health."