Clinical Trials

Bone Marrow Transplant (Hematology)

Keywords

Study Title

Status

AMD3100, Peripheral Blood Stem Cells, Transplantation, RP124Compassionate Use Protocol for the use of AMD3100 to Mobilize Peripheral Blood Stem Cells for Collection and TransplantationOpen to Enrollment
Pediatric Leukemia, Myelodysplasia, Umbilical Cord Blood (UCB Transplantation, RP127Multi-center, Open Label, Randomized Trial Comparing Single versus Double Umbilical Cord Blood (UCB) Transplantation in Pediatric Patients with Leukemia and MyelodysplasiaOpen to Enrollment
Marrow Transplantation, HLA-Matched Family Members, Severe Aplastic Anemia, RP128Cyclophosphamide and Antithymocyte Globulin Conditioning Regimen for Marrow Transplantation from HLA-Matched Family Members for Severe Aplastic Anemia: Effect of Marrow Cell Dose on Chronic Graft-vs.-Host Disease: A Multi-Center TrialOpen to Enrollment
Allogeneic Stem Cell Transplantation, Myelofibrosis, RP129Study of Fludarabine Based Conditioning for Allogeneic Stem Cell Transplantation for MyelofibrosisOpen to Enrollment
Randomized Trial, Prophylaxis, Hematopoietic StemCell Transplantation, Relapsed ALL, RP130A Randomized Trial of Sirolimus-Based Graft versus Host Disease Prophylaxis after Hematopoietic Stem Cell Transplantation in Relapsed ALLOpen to Enrollment
Unrelated bone marrow transplant, unrelated stem cell transplant, allogenetic transplantDevelopment of a National Marrow Donor Program (NMDP) Research Database for Unrelated Stem Cell TransplantionOpen to Enrollment
Unrelated bone marrow transplant, unrelated stem cell transplant, allogenetic transplantNational Marrow Donor Program (NMDP) Research Sample Depository for Unrelated Stem Cell Transplantation ResearchOpen to Enrollment
Stem cell transplantation, bone marrow donationA phase III randomized, multicenter trial comparing G-CSF mobilized peripheral blood stem cell with marrow transplantation from HLA compatible unrelated donorsOpen to Enrollment
Unrelated matched siblings, patients with hematologic malignancies, GVHD, unrelated stem cell transplantStudy to determine the most promising postgrafting immunosuppression for prevention of acute GVHD after unrelated donor G-CSF mobilized peripheral blood monuclear stem cell transplantationOpen to Enrollment
AML >55, Related sibling donors (MRD)Nonmyeloablative Allogeneic Peripheral Blood Stem Cell Transplantation from HLA Matched Related Donors for Treatment of Older Patients with De Novo or Secondary Acute Myeloid Leukemia in First Complete RemissionOpen to Enrollment
Patients with low or falling donor T-cell chimerism s/p NMSCTPentostatin and donor lymphocyte infusion for low donor t-cell chimerism after hematopoietic cell transplantation using nonmyeloablative conditioning - a mulit -center trialOpen to Enrollment
Patients with hematologic malignancies, Allogeneic Bone marrow transplant from HLA-idential sibling donor, single antigen mismatched related or unrelated donor, marrow/PBSC or cord blood available for marrow donationRapamyucin for Immunosuppression and B cell Modulation post stem cell transplant for acute lymphoblastic leukemiaOpen to Enrollment
Patients with hematologic malignanciesStudy comparing myeloablative to nonmyeloablative transplant conditioning in patients with myelodyspastic syndrome or acute myelogenous leukemia. A multi-center Phase III Trial.Open to Enrollment
Patients with hematologic malignaicies (related donor), decreased risk of rejection, no BMT within 6-8 monthsComparison of nonmyeloablative conditioning with TBI versus Fludarabine/TBI for HLA-matched related hematopoietic cell transplantation for treatment of hematologic malignanciesOpen to Enrollment
HLA matched related hematopoetic stem cell transplantation, increased risk of rejection, BMT within 6 monthsStudy of nonmyeloablative conditioning with TBI or fludarabine/TBIOpen to Enrollment
Retrospective Clinical DatabaseInternational Blood and Marrow Transplant Registry (IBMTR) and Autologous Bone Marrow Transplant Registry (ABMTR) - Development of outcomes databasesOpen to Enrollment
Campath, allogeneic transplants with mis-matched related and unrelated donors, RP93Campath [Alemtuzumab] Dose Escalation, Low-Dose TBI and Fludarabine Followed by HLA Class I Mismatched Donor Stem Cell Transplantation for Patients with Hematologic Malignancies - A Multi-Center TrialOpen to Enrollment
Retrospective Clinical Database, RP126Assessment of the Correlation between Pre-transplant Comorbidities and Post-Transplant Outcomes Using the Hematopoietic cell Transplantation-Specific Comorbidity Index (HCT-CI): A Multi-Center TrialOpen to Enrollment
Paroxysmal Nocturnal Hemoglobinuria, Hematopoietic Stem Cell, Prion ProteinRole of Prion Protein in Human Hematopoietic Stem CellsOpen to Enrollment
Pulmonary Hypertension, Myelofibrosis, Bone Marrow, Scarring, FlolanReversible Secondary Myelofibrosis or Clonal Myeloproliferative Disorder Open to Enrollment