Novel Oral Anticoagulants

New/Novel Resources for Health Care Providers

The University of Utah Health Care Thrombosis Service is committed to assisting providers in safely and appropriately incorporating new/novel oral anticoagulants (NOACs) into practice and to providing health care professionals and patients with NOAC-related education. To aid clinicians in the safe and appropriate use of the NOACs, this page provides guidelines for clinical use and management of the NOACs, educational materials and information about requesting thrombosis service consultation if you are considering NOAC therapy and would like assistance. 

Provider Education

NOACs for stroke prevention in atrial fibrillation: A comparison chart (pdf)

NOACs for venous thromboembolism treatment: A comparison chart (pdf)

NOACs summary handout (pdf)

Clinical Guidance Tools

Clinical Management of NOACs

University of Utah providers may refer patients to the thrombosis service for clinical management and follow-up related to novel oral anticoagulant therapy.

Initial consultation with the anticoagulation pharmacist will include the following:

  • Review of indication and complete clinical screening
  • Risk/benefit analysis and discussion
  • Financial/insurance analysis
  • Pre-authorization for drug coverage if needed
  • Individualized treatment recommendations
  • Education about the recommended medication(s)
  • Follow-up with referring provider about treatment recommendations and plan
  • Initiation of therapy
  • Consultation with thrombosis medical directors as necessary

Initial consultations will occur same day to within a couple of days, based on the volume and timing of requests.

Clinical follow-up for patients taking NOACs is important for a variety of reasons and will include the following:

  • Ensuring continued medication compliance and patient’s continued ability to obtain the medication to minimize the risk of thrombotic events due to interruptions in therapy
  • Medication review/reconciliation to monitor for drug interactions
  • Ordering/review of appropriate laboratory parameters to ensure appropriate drug dosing and clearance
  • Monitoring for signs/symptoms of thrombosis/bleeding and other potential adverse effects
  • Designing periprocedural anticoagulation plans to minimize the risk of bleeding/thrombosis pre- and post-procedure

Follow-up chart review will occur at least once monthly, and communication with the patient will take place at a patient-specific interval (no longer than every three months).

To refer a patient for novel oral anticoagulation management:

  • Call the thrombosis service at (801) 585-3713 and choose option one for providers, OR page the Thrombosis Service referral pager at (801) 339-2407
  • Place a referral in Epic:
    -Choose “referral, anticoagulation” in order entry
    -Provide all necessary information  

In any case, the more information you provide, the faster the thrombosis service will be able to assist you!

Patient Education

Helpful Websites

Pradaxa® (dabigatran etexilate)
Copay discount cards/patient assistance   
Xarelto (rivaroxaban)
Copay discount cards/patient assistance   
Eliquis (apixaban) Manufacturer 
Copay discount cards/patient assistance