Novel Platelet Functions in Aging and Venous Thromboembolism (NIH Grant # AG1031065)
An NIH-funded bench-to-bedside investigation studying changes in platelet functions in aging and in patients at risk for venous thromboembolism (IRB_00026265).
Heparin Induced Thrombocytopenia Complicating Medically Ill Patients Receiving Pharmacological Prophylaxis: Prevalence, Management, and Outcomes. A Single Institution Retrospective Analysis (IRB_00015840)
A retrospective analysis of medically ill patients who develop heparin induced thrombocytopenia.
ADOPT: Apixaban Dosing to Optimize Protection from Thrombosis. A study of medically ill deep vein thrombosis prevention using a novel oral Xa-inhibitor, apixaban (IRB_00024994).
RE-SONATE: Dabigatran etexilate in the long-term prevention of recurrent symptomatic venous thromboembolism in patients who have completed 6-18 months of treatment and are considering discontinuation of anticoagulation (IRB_00025795).
AMPLIFY: A Safety and Efficacy Trial Evaluating the Use of Apixaban in the Treatment of Symptomatic Deep Vein Thrombosis and Pulmonary Embolism (IRB_00029133).
BRIDGE: Bridging Anticoagulation in Patients who Require Temporary Interruption of Warfarin Therapy for an Elective Invasive Procedure or Surgery
FDG PET in Cancer Associated Venothromboembolism
An investigation to determine the sensitivity of FDG PET in the diagnosis of acute venothromboembolism and the value of FDG PET in early detection of occult cancer in this population (IRB_00018327).
Improving the Transition of Care from the Inpatient to Outpatient Setting in Patients Newly Started on Warfarin Therapy (IRB_00030733).
Prophylaxis against thrOmboembolism iniTiated in the Emergency department for high-risk medical patieNTs (POTENT): A National Quality Improvement Initiative for Hospitals, Begun in the ED (IRB_00029071).
Immunologic Mechanisms of Acute Lung Injury (IRB_00028210).
A translational investigation studying genetic influences and gene regulatory pathways on the influence of acute lung injury. This study is funded by a grant from the NIH.
Characterization of Novel Platelet Functions in Patients with Cancer (IRB_00026599).
A study to determine if pro-thrombotic pathways are upregulated and/or changed in patients with cancer, thus potentially increasing the risk of thromboembolic disease.
Novel Platelet Functions in Sepsis and Venous Thromboembolism (IRB_00029495).
A translational investigation studying novel platelet functions in patients with sepsis and correlating these activities with the risk of VTE. This study is funded by a grant from the NIH/CCTSA.
The Effects of Linezolid and Vancomycin on Inflammation and Cellular Signaling Events (Pfizer IIR_GA5951WK).
This study will determine if commonly-used antibiotics affect cellular activation and pro-thrombotic signaling events.
