People with this syndrome have dark moles around the mouth, nose, and eyes, as well as multiple polyps in the intestines.
Li-Fraumeni syndrome raises the risk for breast cancer and many other types of cancer.
The risk for breast cancer, gastrointestinal cancers, and thyroid cancer is increased with Cowden syndrome, a rare genetic disorder.
The risk for breast cancer may be increased for women who carry the A-T gene. Ataxia telangiectasia is a rare childhood disease that affects the nervous system and other body systems.
A woman with this syndrome may develop breast cancer before age 50 and is at higher risk for developing cancer in both breasts or in both the breasts and ovaries.