Spectacle Coatings for Pediatric Migraine

Principal Investigator: Bradley Katz
Keywords: migraine , photophobia Department: Ophthalmology-Services
IRB Number: 00065178 Co Investigator: Kevin Brennan
Specialty: Pediatric Neurology, Ophthalmology, Neurology
Sub Specialties: Neuro-Ophthalmology, Headache
Recruitment Status: Not yet recruiting

Contact Information

Bradley Katz

Brief Summary


Objectives: The long-term goal of the project is to reduce the severity and frequency of migraines in child and adolescent patients who are sensitive to light.  The goal of this protocol is to test an optical filter that blocks the wavelengths of light known to trigger migraines.

A co-PI is developing thin film coatings that will be applied to spectacle lenses. In this protocol, the investigators will determine the efficacy these prototype filters in a cohort of migraine patients.

Inclusion Criteria

  1. Must be diagnosed with migraine with aura or migraine without aura
  2. Must have at least 10 headache days per month

Exclusion Criteria

  1. Currently wearing a spectacle tint specifically prescribed for migraine or light sensitivity
  2. Pregnant
  3. Unwilling or unable in the judgment of the investigator to complete the study
  4. Unavailable for any of the study visits
  5. Light sensitive conditions: meningitis, iritis, blepharospasm, albinism
  6. Degenerative diseases of the retina or optic nerve: diabetic retinopathy, ischemic optic neuropathy
  7. Medications known to affect retinal or optic nerve function: hydroxychloroquine, chloroquine, ethambutol, amiodarone, erectile dysfunction drugs
  8. Best corrected visual acuity less than 20/40 in either eye