|Principal Investigator: Robert Tashjian|
|Keywords: Apoptosis , Tumor Suppressor , Genes , Rotator Cuff Tendon , Tears||Department: Orthopedic Surgery Operations|
|IRB Number: 00068284||Co Investigator: Thomas Higgins|
|Specialty: Orthopaedic Surgery, Orthopaedic Surgery, Orthopaedic Surgery|
|Sub Specialties: Shoulder and Elbow, Orthopaedic Trauma|
|Recruitment Status: Active, not recruiting|
Determine overall levels of apoptosis and gene expression in cases versus controls
Case inclusion: Any patient over the age of 40 undergoing arthroscopic rotator cuff surgery for MRI confirmed full-thickness supraspinatus rotator cuff tear by Dr. Tashjian or Dr. Chalmers.
Control inclusion:Any patient over the age of 40 undergoing open reduction internal fixation (ORIF) of a proximal humerus fracture by Dr. Tashjian, Chalmers, Higgins, Kubiak or Rothberg.
Case exclusion: Any patient undergoing rotator cuff surgery without a full-thickness tear or revision surgery.
Control exclusion: Any patient with a prior history of shoulder pain, dysfunction or surgery and any patient with a rotator cuff tear identified at the time of the surgery.