Principal Investigator: Robert Tashjian
Keywords: Apoptosis , Tumor Suppressor , Genes , Rotator Cuff Tendon , Tears Department: Orthopedic Surgery Operations
IRB Number: 00068284 Co Investigator: Thomas Higgins
Specialty: Orthopaedic Surgery, Orthopaedic Surgery, Orthopaedic Surgery
Sub Specialties: Shoulder and Elbow, Orthopaedic Trauma
Recruitment Status: Active, not recruiting

Contact Information

Erin Granger

Simple Summary

Determine overall levels of apoptosis and gene expression in cases versus controls

Inclusion Criteria

Case inclusion: Any patient over the age of 40 undergoing arthroscopic rotator cuff surgery for MRI confirmed full-thickness supraspinatus rotator cuff tear by Dr. Tashjian or Dr. Chalmers.


Control inclusion:Any patient over the age of 40 undergoing open reduction internal fixation (ORIF) of a proximal humerus fracture by Dr. Tashjian, Chalmers, Higgins, Kubiak or Rothberg.

Exclusion Criteria

Case exclusion: Any patient undergoing rotator cuff surgery without a full-thickness tear or revision surgery.


Control exclusion: Any patient with a prior history of shoulder pain, dysfunction or surgery and any patient with a rotator cuff tear identified at the time of the surgery.

Participant Reimbursement