|Principal Investigator: Eun-Kee Jeong|
|Keywords: Spine imaging , MS , MRI||Department: Radiology Research|
|IRB Number: 00076312||Co Investigator: John Rose|
|Sub Specialties: Magnetic Resonance Imaging – MRI|
|Recruitment Status: Recruiting|
Aim 1. Validate if LoHi-B diffusion imaging accurately measures ICF/ECF in cervical spinal cord (CSC). Aim 2: Statistically quantify the variance in ICF, ECF, and BPF of normal volunteers and establish a normative database in the cervical spinal cord. Aim 3: Test whether ICF/ECF/BPF measured LoHi-B DWI provides increased diagnostic values about MS lesions in the CSC.
Age and gender-matched normal subjects will also be recruited from the local population.
For all subjects, there will be an age range or 18-60 with no preference on sex or race, as long as the subject would tolerate the examination for an hour, and written informed consent will be collected prior to any testing under this protocol.