|Principal Investigator: Paul Bernstein|
|Keywords: prenatal vitamins , vision health||Department: Ophthalmology-Services|
|IRB Number: 00116610||Co Investigator: Michael Varner|
|Specialty: Ophthalmology, Ophthalmology|
|Sub Specialties: Retinal Diseases, Comprehensive Ophthalmology|
|Recruitment Status: Recruiting|
The purpose of this study is to characterize the effects of prenatal supplementation with the carotenoids lutein and zeaxanthin both in the mothers and their newborn infants. No OTC prenatal vitamins currently available contain these nutrients, however they are commonly recommended for older adults at risk for developing age-related macular degeneration.
Pregnant women, 18 or older of all races and ethnicities who:
have an uncomplicated obstetric history
plan to deliver either vaginally or by Caesarian section at the University of Utah for their current pregnancy
Women will be excluded if they:
Have regularly taken carotenoid supplements containing more than 0.5 mg of lutein and/or zeaxanthin daily during the past six months.
Have significant eye disease associated with macular pigment abnormalities such as Stargardt disease, albinism, or macular telangiectasia type II (MacTel).
Have any conditions associated with high-risk pregnancies such as adolescent pregnancy, multiparity, current or past history of diabetes, pre-eclampsia, previous premature delivery, drug abuse, or other significant medical illness.
Participants receive OTC prenatal multivitamins for the duration of her pregnancy and through 3 months following delivery, the study supplements, and a total maximum of $125 in gift cards for completing all study visits.