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Frederic C. Clayton

Frederic C. Clayton, MD

Languages spoken: English
  • Dr. Clayton's recent work has focused on the immunologic aspects of allergic diseases.

    Specialties

    • Pathology, Anatomical

    Board Certification

    American Board of Pathology (Sub: Anatomic Path)
  • Dr. Clayton's recent work has focused on the immunologic aspects of allergic diseases.

    Board Certification and Academic Information

    Academic Departments Pathology -Primary
    Board Certification
    American Board of Pathology (Sub: Anatomic Path)

    Education history

    Residency Clinical Pathology - University of Utah School of Medicine Resident
    Anatomic Pathology - M.D. Anderson Cancer Center Fellow
    Fellowship Surgical Pathology - University of Minnesota Hospitals Fellow
    Anatomic Pathology - Stanford University Medical Center Resident
    Internship Anatomic & Clinical Pathology - Stanford University Medical Center Intern
    Medicine - Washington University M.D.
    Undergraduate Rice University B.A.

    Selected Publications

    Journal Article

    1. Boylan KE, Kanth P, Delker D, Hazel MW, Boucher KM, Affolter K, Clayton F, Evason KJ, Jedrzkiewicz J, Pletneva M, Samowitz W, Swanson E, Bronner MP (2023). Three pathologic criteria for reproducible diagnosis of colonic sessile serrated lesion versus hyperplastic polyp. Hum Pathol, 137, 25-35.
    2. Warren KJ, Deering-Rice C, Huecksteadt T, Trivedi S, Venosa A, Reilly C, Sanders K, Clayton F, Wyatt TA, Poole JA, Heller NM, Leung D, Paine R 3rd (2023). Steady-state estradiol triggers a unique innate immune response to allergen resulting in increased airway resistance. Biol Sex Differ, 14(1), 2.
    3. Peterson K, Clayton F, Qeadan F, Gorman D, Robson J, Allen-Brady K, Fang JC (2020). Esophageal Eosinophilia Is Common Among Relatives of Eosinophilic Esophagitis Patients. Clin Gastroenterol Hepatol, 20(5), e957-e963.
    4. COREOS Collaborators, Ma C, Schoepfer AM, Dellon ES, Bredenoord AJ, Chehade M, Collins MH, Feagan BG, Furuta GT, Gupta SK, Hirano I, Jairath V, Katzka DA, Pai RK, Rothenberg ME, Straumann A, Aceves SS, Alexander JA, Arva NC, Atkins D, Biedermann L, Blanchard C, Cianferoni A, Ciriza de Los Rios C, Clayton F, Davis CM, de Bortoli N, Dias JA, Falk GW, Genta RM, Ghaffari G, Gonsalves N, Greuter T, Hopp R, Hsu Blatman KS, Jensen ET, Johnston D, Kagalwalla AF, Larsson HM, Leung J, Louis H, Masterson JC, Menard-Katcher C, Menard-Katcher PA, Moawad FJ, Muir AB, Mukkada VA, Penagini R, Pesek RD, Peterson K, Putnam PE, Ravelli A, Savarino EV, Schlag C, Schreiner P, Simon D, Smyrk TC, Spergel JM, Taft TH, Terreehorst I, Vanuytsel T, Venter C, Vieira MC, Vieth M, Vlieg-Boerstra B, von Arnim U, Walker MM, Wechsler JB, Woodland P, Woosley JT, Yang GY, Zevit N, Safroneeva E (2021). Development of a core outcome set for therapeutic studies in eosinophilic esophagitis (COREOS). J Allergy Clin Immunol, 149(2), 659-670.
    5. Ma C, Schoepfer AM, Safroneeva E, COREOS Collaborators, COREOS Collaborators (2021). Development of a Core Outcome Set for Therapeutic Studies in Eosinophilic Esophagitis (COREOS): An International Multidisciplinary Consensus. Gastroenterology, 161(3), 748-755.
    6. Ma C, Schoepfer AM, Safroneeva E, COREOS Collaborators (2021). A Summary of the Meetings of the Development of a Core Outcome Set for Therapeutic Studies in Eosinophilic Esophagitis (COREOS) International Multidisciplinary Consensus. Gastroenterology, 161(3), 778-784.
    7. Dong ZM, Lin E, Wechsler ME, Weller PF, Klion AD, Bochner BS, Delker DA, Hazel MW, Fairfax K, Khoury P, Akuthota P, Merkel PA, Dyer AM, Langford C, Specks U, Gleich GJ, Chinchilli VM, Raby B, Yandell M, Clayton F (2020). Pulmonary Eosinophilic Granulomatosis with Polyangiitis Has IgG4 Plasma Cells and Immunoregulatory Features. Am J Pathol, 190(7), 1438-1448.
    8. Saffari H, Peterson KA, Leiferman KM, Stabin MG, Krstyen JJ, Clayton FC, Pease LF 3rd, Yap JT, Hoffman JM, Gleich GJ (2019). Oral Administration of 99mTechnetium-Labeled Heparin in Eosinophilic Esophagitis. Mayo Clin Proc, 95(3), 449-458.
    9. Peterson KA, Gleich GJ, Limaye NS, Crispin H, Robson J, Fang J, Saffari H, Clayton F, Leiferman KM (2019). Eosinophil granule major basic protein 1 deposition in eosinophilic esophagitis correlates with symptoms independent of eosinophil counts. Dis Esophagus, 32(11).
    10. Swanson EA, March JK, Clayton F, Couturier MR, Arcega R, Smith R, Evason KJ (2018). Epithelial Inclusions in Gallbladder Specimens Mimic Parasite Infection: Histologic and Molecular Examination of Reported Cystoisospora belli Infection in Gallbladders of Immunocompetent Patients. Am J Surg Pathol, 42(10), 1346-1352.
    11. Peterson KA, Yoshigi M, Hazel MW, Delker DA, Lin E, Krishnamurthy C, Consiglio N, Robson J, Yandell M, Clayton F (2018). RNA sequencing confirms similarities between PPI-responsive oesophageal eosinophilia and eosinophilic oesophagitis. Aliment Pharmacol Ther, 48(2), 219-225.
    12. Li L, Luo C, Song Z, Reyes-Vargas E, Clayton F, Huang J, Jensen P, Chen X (2017). Association of anti-HER2 antibody with graphene oxide for curative treatment of osteosarcoma. Nanomedicine, 14(2), 581-593.
    13. Clayton F, Peterson K (2017). Eosinophilic Esophagitis: Pathophysiology and Definition. Gastrointest Endosc Clin N Am, 28(1), 1-14.
    14. Eroh GD, Clayton FC, Florell SR, Cassidy PB, Chirife A, Marn CF, Valenzuela LO, Campbell MS, Seger J, Rowntree VJ, Leachman SA (2017). Cellular and ultrastructural characterization of the grey-morph phenotype in southern right whales (Eubalaena australis). PLoS One, 12(2), e0171449.

    Case Report

    1. Gutnik L, Goold E, Madsen J, Clayton F, Varghese T, Glasgow R (2020). Primary Esophageal Angiosarcoma. Ann Thorac Surg, 111(5), e365-e367.

    Letter

    1. Kator S, Zurko J, Webb BJ, Balatico MA, Clayton F, Palmer CA, Konopa K, Motyckova G, Ford CD, Ostronoff F (2020). Disseminated toxoplasmosis and haemophagocytic lymphohistiocytosis following chimeric antigen receptor T-cell therapy. [Letter to the editor]. Br J Haematol, 189(1), e4-e6.
    2. Poole A, Girard N, Clayton F, Tantravahi SK (2016). Rapid onset of hemophagocytic lymphohistiocytosis in a patient with refractory chronic lymphocytic leukemia treated with ibrutinib. [Letter to the editor]. Leuk Lymphoma, 58(5), 1258-1261.
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