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Scott A. Langenecker, PhD

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Languages Spoken: English

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Scott A. Langenecker, PhD, is a clinical neuropsychologist and is a Professor of Psychiatry and Adjunct Professor of Psychology at the University of Utah. He completed his training at Marquette University, the Medical College of Wisconsin, Long Island Jewish Medical Center, and the University of Michigan. Dr. Langenecker's clinical work focuses on the lifespan approach to mood and anxiety disorders, with particular focus on life transitions (e.g., adolescence to adulthood). His work includes accessing strengths to achieve greater levels of independence, workplace accommodations, and remediation of weaknesses. He sees patients ages 12 throughout adulthood. His research addresses the neurobiological features of mood disorders, in relation to onset, course, responsivity to treatment, likelihood of attrition, likelihood of recurrence, risk for suicide, impact of childhood adversity, buffering affects of family cohesion, and risk for disability.

Clinical Locations

University Neuropsychiatric Institute
Clinic for Neuropsychology Services

801-581-3258

501 Chipeta Way
Salt Lake City, UT  84108
Map

Specialties

  • Mood Disorders
  • Adult Behavioral Health - Outpatient
  • Child Behavioral Health - Outpatient
  • Psychiatry

Board Certification and Academic Information

Academic Departments Psychiatry - Professor
Academic Divisions Adult Psychiatry

Scott A. Langenecker, PhD, is a clinical neuropsychologist and is a Professor of Psychiatry and Adjunct Professor of Psychology at the University of Utah. He completed his training at Marquette University, the Medical College of Wisconsin, Long Island Jewish Medical Center, and the University of Michigan. Dr. Langenecker's clinical work focuses on the lifespan approach to mood and anxiety disorders, with particular focus on life transitions (e.g., adolescence to adulthood). His work includes accessing strengths to achieve greater levels of independence, workplace accommodations, and remediation of weaknesses. He sees patients ages 12 throughout adulthood. His research addresses the neurobiological features of mood disorders, in relation to onset, course, responsivity to treatment, likelihood of attrition, likelihood of recurrence, risk for suicide, impact of childhood adversity, buffering affects of family cohesion, and risk for disability.

Academic Locations

University Neuropsychiatric Institute

801-581-7952

501 Chipeta Way
Department of Psychiatry
Salt Lake City, UT  84108

Research Statement

Dr. Langenecker's research and clinical work focuses on the lifespan approach to mood and anxiety disorders, with particular focus on life transitions (e.g., adolescence to adulthood). He is developing and adapting biological and cognitive tools to understand ways to identify and treat individuals with a past history of mood disorders to reduce recurrence, decrease episode length and severity, and to improve functioning and quality of life.

Board Certification and Academic Information

Academic Departments Psychiatry - Professor
Academic Divisions Adult Psychiatry

Education History

Postdoctoral Fellowship University of Michigan Medical Center
Clinical and Research Neuropsychology
Postdoctoral Fellow
Internship Albert Einstein College of Medicine
Clinical Psychology
Intern
Doctoral Training Marquette University
Clinical Psychology
Ph.D.
Graduate Training Marquette University
Clinical Psychology
M.S.
Undergraduate University of Wisconsin-Madison
Psychology; History
B.S.
Other Training University of Wisconsin-Stevens Point
Paper Science and Chemical Engineering

Selected Publications - Journal Articles

Journal Article

  1. Shillington AC, Langenecker SA, Shelton RC, Foxworth P, Allen L, Rhodes M, Pesa J, Williamson D, Rovner MH (2020). Development of a patient decision aid for treatment resistant depression. J Affect Disord, 275, 299-306.
  2. Hsu DT, Sankar A, Malik MA, Langenecker SA, Mickey BJ, Love TM (2020). Common neural responses to romantic rejection and acceptance in healthy adults. (Epub ahead of print) Soc Neurosci.
  3. Vesel C, Rashidisabet H, Zulueta J, Stange JP, Duffecy J, Hussain F, Piscitello A, Bark J, Langenecker SA, Young S, Mounts E, Omberg L, Nelson PC, Moore RC, Koziol D, Bourne K, Bennett CC, Ajilore O, Demos AP, Leow A (2020). Effects of mood and aging on keystroke dynamics metadata and their diurnal patterns in a large open-science sample: A BiAffect iOS study. J Am Med Inform Assoc, 27(7), 1007-1018.
  4. Bessette KL, Jacobs RH, Heleniak C, Peters AT, Welsh RC, Watkins ER, Langenecker SA (2020). Malleability of rumination: An exploratory model of CBT-based plasticity and long-term reduced risk for depressive relapse among youth from a pilot randomized clinical trial. PLoS ONE, 15(6), e0233539.
  5. Radoman M, Crane NA, Gorka SM, Weafer J, Langenecker SA, de Wit H, Phan KL (2020). Striatal activation to monetary reward is associated with alcohol reward sensitivity. (Epub ahead of print) Neuropsychopharmacology.
  6. Thomas PJ, Panchamukhi S, Nathan J, Francis J, Langenecker S, Gorka S, Leow A, Klumpp H, Phan KL, Ajilore OA (2020). Graph theoretical measures of the uncinate fasciculus subnetwork as predictors and correlates of treatment response in a transdiagnostic psychiatric cohort. Psychiatr Res Neuroimaging, 299, 111064.
  7. Peterman JS, Marshall DF, Lamping E, Easter RE, Babu P, Langenecker SA, McInnis MG, Ryan KA (2020). Decreased working memory capacity among individuals with a mood disorder who have increased metabolic burden. J Affect Disord, 266, 387-393.
  8. Rubin LH, Langenecker SA, Phan KL, Keating SM, Neigh GN, Weber KM, Maki PM (2020). Remitted depression and cognition in HIV: The role of cortisol and inflammation. Psychoneuroendocrinology, 114, 104609.
  9. Hymen EA, Rao JA, Peters AT, Jenkins LM, Weisenbach SL, Kassel MT, Farah LB, Skerrett KA, Haywood JT, Angers K, Pester B, Baker A, Zubieta JK, Ryan KA, Langenecker SA (2019). Memory differences by sex, but not by previous diagnosis of major depressive disorder. Appl Neuropsychol Adult, 27(2), 134-142.
  10. Langenecker SA, Phillips ML (2019). Innovations in Clinical Neuroscience: Tools, Techniques, and Transformative Frameworks. Biol Psychiatry, 87(4), 308-311.
  11. Passarotti AM, Balaban L, Colman LD, Katz LA, Trivedi N, Liu L, Langenecker SA (2020). A Preliminary Study on the Functional Benefits of Computerized Working Memory Training in Children With Pediatric Bipolar Disorder and Attention Deficit Hyperactivity Disorder. Front Psychol, 10, 3060.
  12. Bessette KL, Karstens AJ, Crane NA, Peters AT, Stange JP, Elverman KH, Morimoto SS, Weisenbach SL, Langenecker SA (2020). A Lifespan Model of Interference Resolution and Inhibitory Control: Risk for Depression and Changes with Illness Progression. (Epub ahead of print) Neuropsychol Rev.
  13. Langenecker SA, Kling LR, Crane NA, Gorka SM, Nusslock R, Damme KSF, Weafer J, de Wit H, Phan KL (2019). Anticipation of monetary reward in amygdala, insula, caudate are predictors of pleasure sensitivity to d-Amphetamine administration. Drug Alcohol Depend, 206, 107725.
  14. Stange JP, Jenkins LM, Pocius S, Kreutzer K, Bessette KL, DelDonno SR, Kling LR, Bhaumik R, Welsh RC, Keilp JG, Phan KL, Langenecker SA (2019). Using resting-state intrinsic network connectivity to identify suicide risk in mood disorders. Psychol Med, 1-11.
  15. Cerny BM, Stange JP, Kling LR, Hamlat EJ, ODonnell LA, Deveney C, Langenecker SA (2019). Self-reported affective biases, but not all affective performance biases, are present in depression remission. Br J Clin Psychol, 58(3), 274-288.
  16. DelDonno SR, Mickey BJ, Pruitt PJ, Stange JP, Hsu DT, Weldon AL, Zubieta JK, Langenecker SA (2019). Influence of childhood adversity, approach motivation traits, and depression on individual differences in brain activation during reward anticipation. Biol Psychol, 146, 107709.
  17. Gorka SM, Young CB, Klumpp H, Kennedy AE, Francis J, Ajilore O, Langenecker SA, Shankman SA, Craske MG, Stein MB, Phan KL (2019). Emotion-based brain mechanisms and predictors for SSRI and CBT treatment of anxiety and depression: a randomized trial. Neuropsychopharmacology, 44(9), 1639-1648.
  18. Sankar A, Yttredahl AA, Fourcade EW, Mickey BJ, Love TM, Langenecker SA, Hsu DT (2019). Dissociable Neural Responses to Monetary and Social Gain and Loss in Women With Major Depressive Disorder. Front Behav Neurosci, 13, 149.
  19. DelDonno SR, Karstens AJ, Cerny B, Kling LR, Jenkins LM, Stange JP, Nusslock R, Shankman SA, Langenecker SA (2019). The Titrated Monetary Incentive Delay Task: Sensitivity, convergent and divergent validity, and neural correlates in an RDoC sample. J Clin Exp Neuropsychol, 41(5), 512-529.
  20. Peters AT, Ren X, Bessette KL, Goldstein BI, West AE, Langenecker SA, Pandey GN (2019). Interplay between pro-inflammatory cytokines, childhood trauma, and executive function in depressed adolescents. J Psychiatr Res, 114, 1-10.
  21. Karstens AJ, Korzun I, Avery ET, Kassel MT, Keelan R, Kales H, Abercrombie H, Eisenlohr-Moul T, Langenecker SA, Weisenbach S (2019). Examining HPA-axis functioning as a mediator of the relationship between depression and cognition across the adult lifespan. Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition, 26(4), 507-520.
  22. Peters AT, Jenkins LM, Stange JP, Bessette KL, Skerrett KA, Kling LR, Welsh RC, Milad MR, Phan KL, Langenecker SA (2019). Pre-scan cortisol is differentially associated with enhanced connectivity to the cognitive control network in young adults with a history of depression. Psychoneuroendocrinology, 104, 219-227.
  23. Fitzgerald JM, Klumpp H, Langenecker S, Phan KL (2018). Transdiagnostic neural correlates of volitional emotion regulation in anxiety and depression. Depress Anxiety, 36(5), 453-464.
  24. Langenecker SA, Klumpp H, Peters AT, Crane NA, DelDonno SR, Bessette KL, Ajilore O, Leow A, Shankman SA, Walker SJ, Ransom MT, Hsu DT, Phan KL, Zubieta JK, Mickey BJ, Stange JP (2019). Multidimensional imaging techniques for prediction of treatment response in major depressive disorder. Prog Neuropsychopharmacol Biol Psychiatry, 91, 38-48.
  25. Langenecker SA, Mickey BJ, Eichhammer P, Sen S, Elverman KH, Kennedy SE, Heitzeg MM, Ribeiro SM, Love TM, Hsu DT, Koeppe RA, Watson SJ, Akil H, Goldman D, Burmeister M, Zubieta JK (2019). Cognitive Control as a 5-HT1A-Based Domain That Is Disrupted in Major Depressive Disorder. Front Psychol, 10, 691.
  26. Caveney AF, Langenecker SA, Pandey AS, Farah LB, Ortiz JA, Huq N, Bhaumik R, Thompson BG, Giordani BJ, Auer D, Morgenstern LB (2019). Neuropsychological Changes in Patients Undergoing Treatment of Unruptured Intracranial Aneurysms. Neurosurgery, 84(3), 581-587.
  27. Burkhouse KL, Stange JP, Jacobs RH, Bhaumik R, Bessette KL, Peters AT, Crane NA, Kreutzer KA, Fitzgerald K, Monk CS, Welsh RC, Phan KL, Langenecker SA (2018). Developmental changes in resting-state functional networks among individuals with and without internalizing psychopathologies. Depress Anxiety, 36(2), 141-152.
  28. Patel PJ, Bhatt T, DelDonno SR, Langenecker SA, Dusane S (2019). Examining Neural Plasticity for Slip-Perturbation Training: An fMRI Study. Front Neurol, 9, 1181.
  29. Jenkins LM, Stange JP, Bessette KL, Chang YS, Corwin SD, Skerrett KA, Patrn VG, Zubieta JK, Crane NA, Passarotti AM, Pine DS, Langenecker SA (2018). Differential engagement of cognitive control regions and subgenual cingulate based upon presence or absence of comorbid anxiety with depression. J Affect Disord, 241, 371-380.
  30. Kling LR, Bessette KL, DelDonno SR, Ryan KA, Drevets WC, McInnis MG, Phillips ML, Langenecker SA (2018). Cluster analysis with MOODS-SR illustrates a potential bipolar disorder risk phenotype in young adults with remitted major depressive disorder. Bipolar Disord, 20(8), 697-707.
  31. Stange JP, Jenkins LM, Bessette KL, Kling LR, Bark JS, Shepard R, Hamlat EJ, DelDonno S, Phan KL, Passarotti AM, Ajilore O, Langenecker SA (2018). Predictors of Attrition in Longitudinal Neuroimaging Research: Inhibitory Control, Head Movement, and Resting-State Functional Connectivity. Brain Connect, 8(9), 527-536.
  32. Quinn ME, Stange JP, Jenkins LM, Corwin S, DelDonno SR, Bessette KL, Welsh RC, Langenecker SA (2017). Cognitive control and network disruption in remitted depression: a correlate of childhood adversity. Soc Cogn Affect Neurosci, 13(10), 1081-1090.
  33. Peters AT, Smith RA, Kassel MT, Hagan M, Maki P, Van Meter A, Briceo EM, Ryan KA, Weldon AL, Weisenbach SL, Starkman MN, Langenecker SA (2018). A pilot investigation of differential neuroendocrine associations with fronto-limbic activation during semantically-cued list learning in mood disorders. J Affect Disord, 239, 180-191.
  34. Manczak EM, Skerrett KA, Gabriel LB, Ryan KA, Langenecker SA (2018). Family support: A possible buffer against disruptive events for individuals with and without remitted depression. J Fam Psychol, 32(7), 926-935.
  35. Bhatt T, Patel P, Dusane S, DelDonno SR, Langenecker SA (2018). Neural Mechanisms Involved in Mental Imagery of Slip-Perturbation While Walking: A Preliminary fMRI Study. Front Behav Neurosci, 12, 203.
  36. Conrin SD, Zhan L, Morrissey ZD, Xing M, Forbes A, Maki P, Milad MR, Ajilore O, Langenecker SA, Leow AD (2018). From Default Mode Network to the Basal Configuration: Sex Differences in the Resting-State Brain Connectivity as a Function of Age and Their Clinical Correlates. Front Psychiatry, 9, 365.
  37. Weine SM, Langenecker S, Arenliu A (2018). Global mental health and the National Institute of Mental Health Research Domain Criteria. Int J Soc Psychiatry, 64(5), 436-442.
  38. Zulueta J, Piscitello A, Rasic M, Easter R, Babu P, Langenecker SA, McInnis M, Ajilore O, Nelson PC, Ryan K, Leow A (2018). Predicting Mood Disturbance Severity with Mobile Phone Keystroke Metadata: A BiAffect Digital Phenotyping Study. J Med Internet Res, 20(7), e241.
  39. Langenecker SA, Jenkins LM, Stange JP, Chang YS, DelDonno SR, Bessette KL, Passarotti AM, Bhaumik R, Ajilore O, Jacobs RH (2018). Cognitive control neuroimaging measures differentiate between those with and without future recurrence of depression. Neuroimage (Amst), 20, 1001-1009.
  40. Bhaumik R, Jenkins LM, Gowins JR, Jacobs RH, Barba A, Bhaumik DK, Langenecker SA (2016). Multivariate pattern analysis strategies in detection of remitted major depressive disorder using resting state functional connectivity. Neuroimage (Amst), 16, 390-398.
  41. Hsu DT, Sanford BJ, Meyers KK, Love TM, Hazlett KE, Wang H, Ni L, Walker SJ, Mickey BJ, Korycinski ST, Koeppe RA, Crocker JK, Langenecker SA, Zubieta JK (2013). Social feedback activates the endogenous opioid system. Mol Psychiatry, 18(11), 1147.
  42. Ryan KA, Vederman AC, McFadden EM, Weldon AL, Kamali M, Langenecker SA, McInnis MG (2012). Differential executive functioning performance by phase of bipolar disorder. Bipolar Disord, 14(5), 527-36.
  43. Nielson KA, Langenecker SA, Ross TJ, Garavan H, Rao SM, Stein EA (2004). Comparability of functional MRI response in young and old during inhibition. Neuroreport, 15(1), 129-33.

Editorial

  1. Phillips ML, Langenecker SA (2019). Welcome. Biol Psychiatry, 85(10S), A11.
  2. Burdick KE, Millett CE, Bonnn CDM, Bowie CR, Carvalho AF, Eyler LT, Gallagher P, Harvey PD, Kessing LV, Lafer B, Langenecker SA, Lewandowski KE, Lpez-Jaramillo C, Marshall DF, Martinez-Aran A, McInnis MG, McIntyre RS, Miskowiak KW, Porter RJ, Purdon SE, Ryan KA, Sumiyoshi T, Torres IJ, Van Rheenen TE, Vieta E, Woodward ND, Yatham LN, Young A (2019). The International Consortium Investigating Neurocognition in Bipolar Disorder (ICONIC-BD). Bipolar Disord, 21(1), 6-10.

Mechanisms of Rumination Change in Adolescent Depression (RuMeChange)

Description: Recruiting Keywords: depression, prevention, rumination, compassion, absorption, brain Principal Investigator: Scott Langenecker

NIC

Description: Recruiting Keywords: nicotine, mild, cognitive, impairment Principal Investigator: Scott Langenecker

Active Moms

Description: Keywords: Principal Investigator: Scott Langenecker

Active RUME

Description: Keywords: Principal Investigator: Scott Langenecker

News Articles

Brain Scans May Provide Clues to Suicide Risk

Feature News

What Doesn’t Kill You May Not Make You Stronger: How Childhood Adversity Affects Resilience Later in Life

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