Brian T. Cain
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Brian T. Cain, MD

Languages spoken: English

Clinical Locations

Primary Location

Huntsman Cancer Institute - Cancer Hospital North

Surgical Oncology
1950 Circle of Hope
Salt Lake City , UT 84112
801-587-5854
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  • Brian T. Cain, MD, is a colorectal surgeon with specialized expertise in the treatment of patients with complex colorectal conditions. He provides comprehensive surgical care for both benign and malignant diseases of the colon, rectum, and small bowel, with advanced training in minimally invasive, robotic, and transanal surgical techniques.

    Clinical Expertise

    Dr. Cain’s clinical practice includes a wide range of colorectal treatments and surgical care, including:

  • Surgical management of cancers of the small bowel, colon, and rectum
  • Inflammatory bowel disease, including Crohn’s disease and ulcerative colitis
  • Diverticulitis and complex fistulas
  • Colonoscopy and advanced endoscopic interventions
  • Minimally invasive surgery, including laparoscopic and robotic approaches
  • Transanal minimally invasive surgery (TAMIS)
  • Pelvic floor disorders
  • Revisional colorectal surgery
  • Pre- and post-surgical management for complex colorectal conditions

    • Education and Training

    Dr. Cain earned his medical degree from the University of Wisconsin School of Medicine and Public Health. He completed his General Surgery residency at the University of Utah, where he received the Department of Surgery Chief Resident Teaching Award for excellence in surgical education. He then pursued fellowship training in Colon and Rectal Surgery at the University of Utah, gaining extensive experience in the surgical and non-surgical management of benign and malignant anorectal diseases, complex fistula repair, advanced endoscopy, and minimally invasive techniques.

    Research and Academic Interests

    Dr. Cain’s research focuses on improving outcomes and patient experiences in colorectal surgery. His current areas of interest include:

  • Socioeconomic effects on surgical outcomes
  • Patient-centered and shared decision-making in surgery

    • Patient-Centered Care

    Dr. Cain partners closely with patients and families to develop individualized treatment plans. He is committed to delivering compassionate, evidence-based care that improves surgical outcomes, quality of life, and long-term colorectal health.

    Personal Interests

    Outside of his clinical practice, Dr. Cain enjoys skiing, hockey, running, hiking, and camping with his wife and two children.

    Specialties

    Board Certification

    American Board of Surgery

  • Brian T. Cain, MD, is a colorectal surgeon with specialized expertise in the treatment of patients with complex colorectal conditions. He provides comprehensive surgical care for both benign and malignant diseases of the colon, rectum, and small bowel, with advanced training in minimally invasive, robotic, and transanal surgical techniques.

    Clinical Expertise

    Dr. Cain’s clinical practice includes a wide range of colorectal treatments and surgical care, including:

  • Surgical management of cancers of the small bowel, colon, and rectum
  • Inflammatory bowel disease, including Crohn’s disease and ulcerative colitis
  • Diverticulitis and complex fistulas
  • Colonoscopy and advanced endoscopic interventions
  • Minimally invasive surgery, including laparoscopic and robotic approaches
  • Transanal minimally invasive surgery (TAMIS)
  • Pelvic floor disorders
  • Revisional colorectal surgery
  • Pre- and post-surgical management for complex colorectal conditions

    • Education and Training

    Dr. Cain earned his medical degree from the University of Wisconsin School of Medicine and Public Health. He completed his General Surgery residency at the University of Utah, where he received the Department of Surgery Chief Resident Teaching Award for excellence in surgical education. He then pursued fellowship training in Colon and Rectal Surgery at the University of Utah, gaining extensive experience in the surgical and non-surgical management of benign and malignant anorectal diseases, complex fistula repair, advanced endoscopy, and minimally invasive techniques.

    Research and Academic Interests

    Dr. Cain’s research focuses on improving outcomes and patient experiences in colorectal surgery. His current areas of interest include:

  • Socioeconomic effects on surgical outcomes
  • Patient-centered and shared decision-making in surgery

    • Patient-Centered Care

    Dr. Cain partners closely with patients and families to develop individualized treatment plans. He is committed to delivering compassionate, evidence-based care that improves surgical outcomes, quality of life, and long-term colorectal health.

    Personal Interests

    Outside of his clinical practice, Dr. Cain enjoys skiing, hockey, running, hiking, and camping with his wife and two children.

    Board Certification and Academic Information

    Academic Departments Surgery -Assistant Professor (Clinical)
    Academic Divisions Surgical Oncology
    Board Certification
    American Board of Surgery

    Education history

    Fellowship Colon and Rectal Surgery - University of Utah Health Fellow
    Residency General Surgery - University of Utah Health Resident
    Professional Medical Medicine - University of Wisconsin School of Medicine and Public Health M.D.
    Undergraduate Biology and Zoology - University of Wisconsin-Madison B.S.

    Selected Publications

    Journal Article

    1. Williamson AJH, Cain BT, Hoggan TJ, Larsen MW, Kimball ER, Bloomquist K, Galyean PO, Zickmund S, Cohan JN (2023). Challenges and Opportunities in the Elective Management of Diverticulitis: Perspectives From a National Sample of Colorectal Surgeons. Dis Colon Rectum, 67(2), 264-272. (Read full publication)
    2. Bleicher J, Johnson JE, Cain BT, Shaw RD, Acher AA, Gleason L, Barth RJ, Chu DI, Jung S, Melnick D, Kaphingst KA, Smith BK, Huang LC (2023). Surgical Trainee Perspectives on the Opioid Crisis: The Influence of Explicit and Hidden Curricula. J Surg Educ, 80(6), 786-796. (Read full publication)
    3. Johnson JE, Bleicher J, Blumling AN, Cain BT, Cohan JN, Savarise M, Harris AHS, Kaphingst KA, Huang LC (2022). The Influence of Rural Healthcare Systems and Communities on Surgery and Recovery: A Qualitative Study. J Surg Res, 281, 155-163. (Read full publication)
    4. Bleicher J, Fender Z, Johnson JE, Cain BT, Phan K, Powers D, Wei G, Presson AP, Kwok A, Pickron TB, Scaife CL, Huang LC (2021). Use of post-discharge opioid consumption patterns as a tool for evaluating opioid prescribing guidelines. Am J Surg, 224(1 Pt A), 58-63. (Read full publication)
    5. Cain BT, Horns JJ, Huang LC, McCrum ML (2022). Socioeconomic disadvantage is associated with greater mortality after high-risk emergency general surgery. J Trauma Acute Care Surg, 92(4), 691-700. (Read full publication)
    6. Cain BT, Huang LC (2021). Benign Colonic Strictures. Dis Colon Rectum, 64(9), 1041-1044. (Read full publication)
    7. Mohns MS, Greene JM, Cain BT, Pham NH, Gostick E, Price DA, OConnor DH (2015). Expansion of Simian Immunodeficiency Virus (SIV)-Specific CD8 T Cell Lines from SIV-Naive Mauritian Cynomolgus Macaques for Adoptive Transfer. J Virol, 89(19), 9748-57. (Read full publication)
    8. Ericsen AJ, Starrett GJ, Greene JM, Lauck M, Raveendran M, Deiros DR, Mohns MS, Vince N, Cain BT, Pham NH, Weinfurter JT, Bailey AL, Budde ML, Wiseman RW, Gibbs R, Muzny D, Friedrich TC, Rogers J, OConnor DH (2014). Whole genome sequencing of SIV-infected macaques identifies candidate loci that may contribute to host control of virus replication. Genome Biol, 15(11), 478. (Read full publication)
    9. Greene JM, Weiler AM, Reynolds MR, Cain BT, Pham NH, Ericsen AJ, Peterson EJ, Crosno K, Brunner K, Friedrich TC, OConnor DH (2014). Rapid, repeated, low-dose challenges with SIVmac239 infect animals in a condensed challenge window. Retrovirology, 11, 66. (Read full publication)
    10. Cain BT, Pham NH, Budde ML, Greene JM, Weinfurter JT, Scarlotta M, Harris M, Chin E, OConnor SL, Friedrich TC, OConnor DH (2013). T cell response specificity and magnitude against SIVmac239 are not concordant in major histocompatibility complex-matched animals. Retrovirology, 10, 116. (Read full publication)
    11. Greene JM, Lhost JJ, Hines PJ, Scarlotta M, Harris M, Burwitz BJ, Budde ML, Dudley DM, Pham N, Cain B, Mac Nair CE, Weiker MK, OConnor SL, Friedrich TC, OConnor DH (2013). Adoptive transfer of lymphocytes isolated from simian immunodeficiency virus SIVmac239Δnef-vaccinated macaques does not affect acute-phase viral loads but may reduce chronic-phase viral loads in major histocompatibility complex-matched recipients. J Virol, 87(13), 7382-92. (Read full publication)
    12. Maiden SL, Harrison N, Keegan J, Cain B, Lynch AM, Pettitt J, Hardin J (2012). Specific conserved C-terminal amino acids of Caenorhabditis elegans HMP-1/α-catenin modulate F-actin binding independently of vinculin. J Biol Chem, 288(8), 5694-706. (Read full publication)
    13. Budde ML, Greene JM, Chin EN, Ericsen AJ, Scarlotta M, Cain BT, Pham NH, Becker EA, Harris M, Weinfurter JT, OConnor SL, Piatak M Jr, Lifson JD, Gostick E, Price DA, Friedrich TC, OConnor DH (2012). Specific CD8+ T cell responses correlate with control of simian immunodeficiency virus replication in Mauritian cynomolgus macaques. J Virol, 86(14), 7596-604. (Read full publication)