Brian T. Cain
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Brian T. Cain, MD

Languages spoken: English

Clinical Locations

Primary Location

Huntsman Cancer Institute - Cancer Hospital North

Surgical Oncology
1950 Circle of Hope
Salt Lake City , UT 84112
801-587-5854
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Brian T. Cain, MD, is a colorectal surgeon with specialized expertise in the treatment of patients with complex colorectal conditions. He provides comprehensive surgical care for both benign and malignant diseases of the colon, rectum, and small bowel, with advanced training in minimally invasive, robotic, and transanal surgical techniques.

Clinical Expertise

Dr. Cain’s clinical practice includes a wide range of colorectal treatments and surgical care, including:

  • Surgical management of cancers of the small bowel, colon, and rectum
  • Inflammatory bowel disease, including Crohn’s disease and ulcerative colitis
  • Diverticulitis and complex fistulas
  • Colonoscopy and advanced endoscopic interventions
  • Minimally invasive surgery, including laparoscopic and robotic approaches
  • Transanal minimally invasive surgery (TAMIS)
  • Pelvic floor disorders
  • Revisional colorectal surgery
  • Pre- and post-surgical management for complex colorectal conditions

Education and Training

Dr. Cain earned his medical degree from the University of Wisconsin School of Medicine and Public Health. He completed his General Surgery residency at the University of Utah, where he received the Department of Surgery Chief Resident Teaching Award for excellence in surgical education. He then pursued fellowship training in Colon and Rectal Surgery at the University of Utah, gaining extensive experience in the surgical and non-surgical management of benign and malignant anorectal diseases, complex fistula repair, advanced endoscopy, and minimally invasive techniques.

Research and Academic Interests

Dr. Cain’s research focuses on improving outcomes and patient experiences in colorectal surgery. His current areas of interest include:

  • Socioeconomic effects on surgical outcomes
  • Patient-centered and shared decision-making in surgery

Patient-Centered Care

Dr. Cain partners closely with patients and families to develop individualized treatment plans. He is committed to delivering compassionate, evidence-based care that improves surgical outcomes, quality of life, and long-term colorectal health.

Personal Interests

Outside of his clinical practice, Dr. Cain enjoys skiing, hockey, running, hiking, and camping with his wife and two children.

Specialties

Board Certification

American Board of Surgery

Brian T. Cain, MD, is a colorectal surgeon with specialized expertise in the treatment of patients with complex colorectal conditions. He provides comprehensive surgical care for both benign and malignant diseases of the colon, rectum, and small bowel, with advanced training in minimally invasive, robotic, and transanal surgical techniques.

Clinical Expertise

Dr. Cain’s clinical practice includes a wide range of colorectal treatments and surgical care, including:

  • Surgical management of cancers of the small bowel, colon, and rectum
  • Inflammatory bowel disease, including Crohn’s disease and ulcerative colitis
  • Diverticulitis and complex fistulas
  • Colonoscopy and advanced endoscopic interventions
  • Minimally invasive surgery, including laparoscopic and robotic approaches
  • Transanal minimally invasive surgery (TAMIS)
  • Pelvic floor disorders
  • Revisional colorectal surgery
  • Pre- and post-surgical management for complex colorectal conditions

Education and Training

Dr. Cain earned his medical degree from the University of Wisconsin School of Medicine and Public Health. He completed his General Surgery residency at the University of Utah, where he received the Department of Surgery Chief Resident Teaching Award for excellence in surgical education. He then pursued fellowship training in Colon and Rectal Surgery at the University of Utah, gaining extensive experience in the surgical and non-surgical management of benign and malignant anorectal diseases, complex fistula repair, advanced endoscopy, and minimally invasive techniques.

Research and Academic Interests

Dr. Cain’s research focuses on improving outcomes and patient experiences in colorectal surgery. His current areas of interest include:

  • Socioeconomic effects on surgical outcomes
  • Patient-centered and shared decision-making in surgery

Patient-Centered Care

Dr. Cain partners closely with patients and families to develop individualized treatment plans. He is committed to delivering compassionate, evidence-based care that improves surgical outcomes, quality of life, and long-term colorectal health.

Personal Interests

Outside of his clinical practice, Dr. Cain enjoys skiing, hockey, running, hiking, and camping with his wife and two children.

Board Certification and Academic Information

Academic Departments Surgery -Assistant Professor (Clinical)
Academic Divisions Surgical Oncology
Board Certification
American Board of Surgery

Education history

Undergraduate Biology and Zoology - University of Wisconsin-Madison B.S.
Professional Medical Medicine - University of Wisconsin School of Medicine and Public Health M.D.
Residency General Surgery - University of Utah Health Resident
Fellowship Colon and Rectal Surgery - University of Utah Health Fellow

Selected Publications

Journal Article

  1. Williamson AJH, Cain BT, Hoggan TJ, Larsen MW, Kimball ER, Bloomquist K, Galyean PO, Zickmund S, Cohan JN (2024). Challenges and Opportunities in the Elective Management of Diverticulitis: Perspectives From a National Sample of Colorectal Surgeons. Dis Colon Rectum, 67(2), 264-272.
  2. Bleicher J, Johnson JE, Cain BT, Shaw RD, Acher AA, Gleason L, Barth RJ, Chu DI, Jung S, Melnick D, Kaphingst KA, Smith BK, Huang LC (2023). Surgical Trainee Perspectives on the Opioid Crisis: The Influence of Explicit and Hidden Curricula. J Surg Educ, 80(6), 786-796.
  3. Johnson JE, Bleicher J, Blumling AN, Cain BT, Cohan JN, Savarise M, Harris AHS, Kaphingst KA, Huang LC (2023). The Influence of Rural Healthcare Systems and Communities on Surgery and Recovery: A Qualitative Study. J Surg Res, 281, 155-163.
  4. Cain BT, Horns JJ, Huang LC, McCrum ML (2022). Socioeconomic disadvantage is associated with greater mortality after high-risk emergency general surgery. J Trauma Acute Care Surg, 92(4), 691-700.
  5. Bleicher J, Fender Z, Johnson JE, Cain BT, Phan K, Powers D, Wei G, Presson AP, Kwok A, Pickron TB, Scaife CL, Huang LC (2022). Use of post-discharge opioid consumption patterns as a tool for evaluating opioid prescribing guidelines. Am J Surg, 224(1 Pt A), 58-63.
  6. Cain BT, Huang LC (2021). Benign Colonic Strictures. Dis Colon Rectum, 64(9), 1041-1044.
  7. Mohns MS, Greene JM, Cain BT, Pham NH, Gostick E, Price DA, O'Connor DH (2015). Expansion of Simian Immunodeficiency Virus (SIV)-Specific CD8 T Cell Lines from SIV-Naive Mauritian Cynomolgus Macaques for Adoptive Transfer. J Virol, 89(19), 9748-57.
  8. Ericsen AJ, Starrett GJ, Greene JM, Lauck M, Raveendran M, Deiros DR, Mohns MS, Vince N, Cain BT, Pham NH, Weinfurter JT, Bailey AL, Budde ML, Wiseman RW, Gibbs R, Muzny D, Friedrich TC, Rogers J, O'Connor DH (2014). Whole genome sequencing of SIV-infected macaques identifies candidate loci that may contribute to host control of virus replication. Genome Biol, 15(11), 478.
  9. Greene JM, Weiler AM, Reynolds MR, Cain BT, Pham NH, Ericsen AJ, Peterson EJ, Crosno K, Brunner K, Friedrich TC, O'Connor DH (2014). Rapid, repeated, low-dose challenges with SIVmac239 infect animals in a condensed challenge window. Retrovirology, 11, 66.
  10. Cain BT, Pham NH, Budde ML, Greene JM, Weinfurter JT, Scarlotta M, Harris M, Chin E, O'Connor SL, Friedrich TC, O'Connor DH (2013). T cell response specificity and magnitude against SIVmac239 are not concordant in major histocompatibility complex-matched animals. Retrovirology, 10, 116.
  11. Greene JM, Lhost JJ, Hines PJ, Scarlotta M, Harris M, Burwitz BJ, Budde ML, Dudley DM, Pham N, Cain B, Mac Nair CE, Weiker MK, O'Connor SL, Friedrich TC, O'Connor DH (2013). Adoptive transfer of lymphocytes isolated from simian immunodeficiency virus SIVmac239¿nef-vaccinated macaques does not affect acute-phase viral loads but may reduce chronic-phase viral loads in major histocompatibility complex-matched recipients. J Virol, 87(13), 7382-92.
  12. Maiden SL, Harrison N, Keegan J, Cain B, Lynch AM, Pettitt J, Hardin J (2013). Specific conserved C-terminal amino acids of Caenorhabditis elegans HMP-1/¿-catenin modulate F-actin binding independently of vinculin. J Biol Chem, 288(8), 5694-706.
  13. Budde ML, Greene JM, Chin EN, Ericsen AJ, Scarlotta M, Cain BT, Pham NH, Becker EA, Harris M, Weinfurter JT, O'Connor SL, Piatak M Jr, Lifson JD, Gostick E, Price DA, Friedrich TC, O'Connor DH (2012). Specific CD8+ T cell responses correlate with control of simian immunodeficiency virus replication in Mauritian cynomolgus macaques. J Virol, 86(14), 7596-604.