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Eric A. Smith
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Eric A. Smith, MD, PhD

Languages spoken: English

Clinical Locations

Primary Location

Huntsman Cancer Institute - Cancer Hospital South

Pathology
1950 Circle of Hope
Salt Lake City , UT 84112

University of Utah Hospital

Pathology
50 N Medical Dr
Salt Lake City , UT 84132

ARUP

Hematopathology
500 Chipeta Way
Salt Lake City , UT 84108

Craig H. Neilsen Rehabilitation Hospital

Pathology
85 N Medical Drive
Salt Lake City , UT 84132

Specialties

  • Pathology, Anatomical
  • Molecular Genetic Pathology

Board Certification

American Board of Pathology (Anatomic)
American Board of Pathology (Clinical Path)
American Board of Pathology (Sub: Molecular Genetic Pathology)

Board Certification and Academic Information

Academic Departments Pathology -Research Instructor
Board Certification
American Board of Pathology (Anatomic)
American Board of Pathology (Clinical Path)
American Board of Pathology (Sub: Molecular Genetic Pathology)

Education history

Undergraduate Chemistry, Biochemistry & Molecular Biology - Rose¿Hulman Institute of Technology B.S.
Professional Medical Cancer and Cell Biology - University of Cincinnati College of Medicine M.D., Ph.D.
Residency Anatomic and Clinical Pathology, Physician-Scientist Track - University of Utah Health, ARUP Laboratories Resident
Fellowship Molecular Genetic Pathology - University of Utah Health, ARUP Laboratories Fellow

Selected Publications

Journal Article

  1. Zhang Y, Urquijo MA, Zitnay RG, Marks K, Belote RL, Hansen MMK, Ferita M, Neuendorf HM, Liu T, Smith EA, Mehrabad EM, Hejna M, Moustafa TE, Lange D, Hu M, Vand-Rajabpour F, Done A, Becker CA, Lieberman M, Chang M, Lohman BK, Stubben CJ, Reeves MQ, Zhang X, Weinberger LS, VanBrocklin MW, Deacon DC, Grossman D, Spike BT, Lex A, Boyle GM, Kulkarni R, Zangle TA, Judson-Torres R (2025). A BRN2:MYC transcriptional axis regulates interconversion between therapy-resistant and tumorigenic phenotypes in melanoma. Cell reports, 44(12), 116675.
  2. Chhibber T, Scherzer MT, Prokofyeva A, Becker C, Zitnay RG, Smith E, Khurana N, Skliar M, Deacon DC, VanBrocklin MW, Ghandehari H, Judson-Torres RL, Jafari (2025). Transdermal delivery of ultradeformable cationic liposomes complexed with miR211-5p (UCL-211) stabilizes BRAFV600E+ melanocytic nevi. Journal of controlled release, 381, 113586.
  3. Smith EA, Belote RL, Cruz NM, Moustafa TE, Becker CA, Jiang A, Alizada S, Prokofyeva A, Chan TY, Seasor TA, Balatico M, Cortes-Sanchez E, Lum DH, Hyngstrom JR, Zeng H, Deacon DC, Grossmann AH, White RM, Zangle TA, Judson-Torres RL (2024). Receptor tyrosine kinase inhibition leads to regression of acral melanoma by targeting the tumor microenvironment. J Exp Clin Cancer Res, 43(1), 317.
  4. Chhibber T, Scherzer MT, Prokofyeva A, Becker C, Zitnay RG, Smith E, Khurana N, Skliar M, Deacon DC, VanBrocklin MW, Ghandehari H, Judson-Torres RL, Jafari P (2024). Transdermal Delivery of Ultradeformable Cationic Liposomes Complexed with miR211-5p (UCL-211) Stabilizes BRAFV600E+ Melanocytic Nevi. J Control Release, 381(113586).
  5. Smith EA, Parker R, Genesi B, Yang YK (2022). Have you caught that outlier yet? Evaluate the utility of repeat testing in nutritional and toxic element assessment. Clin Chim Acta, 528, 84-89.
  6. Deacon DC, Smith EA, Judson-Torres RL (2021). Molecular Biomarkers for Melanoma Screening, Diagnosis and Prognosis: Current State and Future Prospects. Front Med (Lausanne), 8, 642380.
  7. Grossman D, Okwundu N, Bartlett EK, Marchetti MA, Othus M, Coit DG, Hartman RI, Leachman SA, Berry EG, Korde L, Lee SJ, Bar-Eli M, Berwick M, Bowles T, Buchbinder EI, Burton EM, Chu EY, Curiel-Lewandrowski C, Curtis JA, Daud A, Deacon DC, Ferris LK, Gershenwald JE, Grossmann KF, Hu-Lieskovan S, Hyngstrom J, Jeter JM, Judson-Torres RL, Kendra KL, Kim CC, Kirkwood JM, Lawson DH, Leming PD, Long GV, Marghoob AA, Mehnert JM, Ming ME, Nelson KC, Polsky D, Scolyer RA, Smith EA, Sondak VK, Stark MS, Stein JA, Thompson JA, Thompson JF, Venna SS, Wei ML, Swetter SM (2020). Prognostic Gene Expression Profiling in Cutaneous Melanoma: Identifying the Knowledge Gaps and Assessing the Clinical Benefit. JAMA Dermatol, 156(9), 1004-1011.
  8. Oltvai ZN, Smith EA, Wiens K, Nogee LM, Luquette M, Nelson AC, Wikenheiser-Brokamp KA (2020). Neonatal respiratory failure due to novel compound heterozygous mutations in the ABCA3 lipid transporter. Cold Spring Harb Mol Case Stud, 6(3).
  9. Smith EA, Krumpelbeck EF, Jegga AG, Prell M, Matrka MM, Kappes F, Greis KD, Ali AM, Meetei AR, Wells SI (2018). The nuclear DEK interactome supports multi-functionality. Proteins, 86(1), 88-97.
  10. Serrano-Lopez J, Nattamai K, Pease NA, Shephard MS, Wellendorf AM, Sertorio M, Smith EA, Geiger H, Wells SI, Cancelas JA, Privette Vinnedge LM (2018). Loss of DEK induces radioresistance of murine restricted hematopoietic progenitors. Exp Hematol, 59, 40-50.e3.
  11. Smith EA, Kumar B, Komurov K, Smith SM, Brown NV, Zhao S, Kumar P, Teknos TN, Wells SI (2017). DEK associates with tumor stage and outcome in HPV16 positive oropharyngeal squamous cell carcinoma. Oncotarget, 8(14), 23414-23426.
  12. Smith EA, Gole B, Willis NA, Soria R, Starnes LM, Krumpelbeck EF, Jegga AG, Ali AM, Guo H, Meetei AR, Andreassen PR, Kappes F, Vinnedge LM, Daniel JA, Scully R, Wiesmüller L, Wells SI (2017). DEK is required for homologous recombination repair of DNA breaks. Sci Rep, 7, 44662.
  13. O¿Toole KT, Martinez A, Murphy B, Fort G, Al-Sudani F, Prokofyeva A, Boggaram S, Smith EA, Paine EL, Baral D ¿ Lum DL, Zhang W, Egal E, Parkman GL, Snyder EL, Judson-Torres R, Andersen JL, McMahon M Identification and characterization of BRAF⇔TP53 interactions in melanoma. Cell Rep,
  14. Becker CA, Mwelwa DWN, Jiang AZ, Huntsman A, Boucher KM, Stubben CJ, Smith EA, Deacon DC, Grossman D, Judson-Torres R Non-invasive adhesive patch microRNA assay recapitulates tissue biomarkers for melanoma. Clinical and translational medicine,
  15. Wang J, Wee Y, Gupta P, Jacob T, Brooks DM, Rogers A, Sorensen LK, Tay JKH, Wilson EC, Liu T, Smith EA, Gopal YNV, Davies MA, McMahon M, Homen SL, Judson-Torres RL, Wolff RK, Grossmann A Rapid activation of ARF6 upon RAF inhibition augments a dynamic pool of BRAFV600E and promotes therapy resistance. Oncogene,