(
out of
48
reviews
)
Specialties
Board Certification
|
American Board of Obesity Medicine
American Board of Internal Medicine
American Board of Internal Medicine (Sub: Gastroenterology)
|
Patient Rating
5.0
/5
( out of
48 reviews
)
The patient rating score is an average of all responses on our patient experience survey. The rating averages scores for all questions about care from our providers. The scale on which responses are measured is 1 to 5 with 5 being the best score.
Patient comments are gathered from our patient experience survey and displayed in their entirety. For the convenience of our visitors, some patient comments have been translated from their original language into English while preserving their original meaning as accurately as possible. Patients are de-identified for confidentiality and patient privacy.
Board Certification and Academic Information
| Academic Departments |
Internal Medicine
-Assistant Professor |
|---|---|
| Academic Divisions |
Gastroenterology
|
| Board Certification |
American Board of Obesity Medicine
American Board of Internal Medicine
American Board of Internal Medicine (Sub: Gastroenterology)
|
Education history
| Undergraduate | Biology - University of Texas at Austin | B.S. |
|---|---|---|
| Professional Medical | Medicine - Perelman School of Medicine at the University of Pennsylvania | M.D. |
| Doctoral Training | Cancer Biology - Perelman School of Medicine at the University of Pennsylvania | Ph.D. |
| Internship | Internal Medicine - Johns Hopkins Hospital | Intern |
| Residency | Internal Medicine - Johns Hopkins Hospital | Resident |
| Fellowship | Gastroenterology & Hepatology - Massachusetts General Hospital | Research and Clinical Fellow |
| Postdoctoral Training | Massachusetts Institute of Technology | Postdoctoral Researcher |
Selected Publications
Journal Article
- Shay JES, Chi F, Tzouanas CN, Hoeve JT, Williams KJ, Sever T, Fuentes I, Yilmaz Ö (2025). Dietary lipids, not ketone body metabolites, influence intestinal tumorigenesis in a ketogenic diet. bioRxiv,
- Chi F, Zhang Q, Shay JES, Hoeve JT, Yuan Y, Yang Z, Shin H, Solanki S, Shah YM, Agudo J, Yilmaz Ö (2025). Dietary cysteine enhances intestinal stemness via CD8(+) T cell-derived IL-22. bioRxiv,
- Corey KE, Nakrour N, Bethea ED, Shay JE, Andersson KL, Bhan I, Friedman LS, Kambadakone AR, Dichtel LE, Chung RT, Harisinghani (2025). Real-World Assessment of Liver Corrected T1 and Magnetic Resonance Elastography in Predicting Liver Disease Progression. Liver international, 45(9), e70280.
- Tzouanas CN, Sherman MS, Shay JES, Rubin AJ, Mead BE, Dao TT, Butzlaff T, Mana MD, Kolb KE, Walesky C, Pepe-Mooney BJ, Smith CJ, Prakadan SM, Ramseier ML, Tong EY, Joung J, Chi F, McMahon-Skates T, Winston CL, Jeong WJ, Aney KJ, Chen E, Nissim S, Zhang F, Deshpande V, Lauer GM, Yilmaz ÖH, Goessling W, Shalek AK (2023). Chronic metabolic stress drives developmental programs and loss of tissue functions in non-transformed liver that mirror tumor states and stratify survival. bioRxiv.
- Shay JES, Vannier A, Tsai S, Mahle R, Diaz PM, Przybyszewski E, Challa PK, Patel SJ, Suzuki J, Schaefer E, Goodman RP, Luther J (2023). Moderate-high intensity exercise associates with reduced incident alcohol-associated liver disease in high-risk patients. Alcohol Alcohol, 58(5), 472-477.
- Su A, Almazan E, Sakulsaengprapha V, Shay J, Wittstein I, Hammami M, Pustavoitau A, Rizkalla N, Alqahtani S, Woreta T, Hamilton JP, Kohli R, Ottmann SE, Gurakar A, Chen PH (2023). High Coronary Artery Calcium Score Is Associated With Increased Major Adverse Cardiac Events After Liver Transplantation. Transplant Direct, 9(2), e1426.
- Vannier AGL, Przybyszewski EM, Shay J, Patel SJ, Schaefer E, Goodman RP, Luther J (2023). Psychotherapy for Alcohol Use Disorder Is Associated With Reduced Risk of Incident Alcohol-Associated Liver Disease. Clin Gastroenterol Hepatol, 21(6), 1571-1580.e7.
- Kummerlowe C, Mwakamui S, Hughes TK, Mulugeta N, Mudenda V, Besa E, Zyambo K, Shay JES, Fleming I, Vukovic M, Doran BA, Aicher TP, Wadsworth MH 2nd, Bramante JT, Uchida AM, Fardoos R, Asowata OE, Herbert N, Yilmaz ÖH, Kløverpris HN, Garber JJ, Ordovas-Montañes J, Gartner ZJ, Wallach T, Shalek AK, Kelly P (2022). Single-cell profiling of environmental enteropathy reveals signatures of epithelial remodeling and immune activation. Sci Transl Med, 14(660), eabi8633.
- Vannier AGL, Shay JES, Fomin V, Patel SJ, Schaefer E, Goodman RP, Luther J (2022). Incidence and Progression of Alcohol-Associated Liver Disease After Medical Therapy for Alcohol Use Disorder. JAMA Netw Open, 5(5), e2213014.
- DiGiacomo DV, Shay JE, Crotty R, Yang N, Bloom P, Corey K, Barmettler S, Farmer JR (2022). Liver Stiffness by Transient Elastography Correlates With Degree of Portal Hypertension in Common Variable Immunodeficiency Patients With Nodular Regenerative Hyperplasia. Front Immunol, 13, 864550.
- Li DK, Platt JM, Shay JES, Yarze JC (2019). Sterile cerebrospinal fluid ascites presenting as high SAAG ascites: a case report. BMC Gastroenterol, 19(1), 200.
- James TW, Shay JES, Furfaro D, Ozseker B, Russell SD, Pustavoitau A, Rizkalla N, Saberi B, Philosophe B, Cameron AM, Gurakar A (2019). Cardiac Events Within the 30-Day Postoperative Period Is Associated With Increased 1-Year Mortality Among Deceased-Donor Liver Transplant Recipients. Exp Clin Transplant, 17(3), 370-374.
- Lin N, Shay JES, Xie H, Lee DSM, Skuli N, Tang Q, Zhou Z, Azzam A, Meng H, Wang H, FitzGerald GA, Simon MC (2018). Myeloid Cell Hypoxia-Inducible Factors Promote Resolution of Inflammation in Experimental Colitis. Front Immunol, 9, 2565.
- Krock BL, Eisinger-Mathason TS, Giannoukos DN, Shay JE, Gohil M, Lee DS, Nakazawa MS, Sesen J, Skuli N, Simon MC (2015). The aryl hydrocarbon receptor nuclear translocator is an essential regulator of murine hematopoietic stem cell viability. Blood, 125(21), 3263-72.
- Mucaj V, Lee SS, Skuli N, Giannoukos DN, Qiu B, Eisinger-Mathason TS, Nakazawa MS, Shay JE, Gopal PP, Venneti S, Lal P, Minn AJ, Simon MC, Mathew LK (2015). MicroRNA-124 expression counteracts pro-survival stress responses in glioblastoma. Oncogene, 34(17), 2204-14.
- Shay JE, Imtiyaz HZ, Sivanand S, Durham AC, Skuli N, Hsu S, Mucaj V, Eisinger-Mathason TS, Krock BL, Giannoukos DN, Simon MC (2014). Inhibition of hypoxia-inducible factors limits tumor progression in a mouse model of colorectal cancer. Carcinogenesis, 35(5), 1067-77.
- Eisinger-Mathason TS, Zhang M, Qiu Q, Skuli N, Nakazawa MS, Karakasheva T, Mucaj V, Shay JE, Stangenberg L, Sadri N, Puré E, Yoon SS, Kirsch DG, Simon MC (2013). Hypoxia-dependent modification of collagen networks promotes sarcoma metastasis. Cancer Discov, 3(10), 1190-205.
- Wise DR, Ward PS, Shay JE, Cross JR, Gruber JJ, Sachdeva UM, Platt JM, DeMatteo RG, Simon MC, Thompson CB (2011). Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of ¿-ketoglutarate to citrate to support cell growth and viability. Proc Natl Acad Sci U S A, 108(49), 19611-6.
Review
- Shay JES, Yilmaz ÖH (2024). Dietary and metabolic effects on intestinal stem cells in health and disease. [Review]. Nat Rev Gastroenterol Hepatol.
- Shay JES, Singh A (2023). The Effect of Obesity on Gastrointestinal Disease. [Review]. Gastroenterol Clin North Am, 52, (2), 403-415.
- Shay JES, Hamilton JP (2018). Hepatic fibrosis: Avenues of investigation and clinical implications. [Review]. Clin Liver Dis (Hoboken), 11, (5), 111-114.
- Mucaj V, Shay JE, Simon MC (2012). Effects of hypoxia and HIFs on cancer metabolism. [Review]. Int J Hematol, 95, (5), 464-70.
- Shay JE, Celeste Simon M (2012). Hypoxia-inducible factors: crosstalk between inflammation and metabolism. [Review]. Semin Cell Dev Biol, 23, (4), 389-94.
Dr Shay was Fantastic
Dr Shay is the best
Excellent listener and at explaining things. Very clear, Caring, Knowledgeable, Took the time to understand. Answered all my many questions.
Dr Shay was very good. I just wanted to use this space to comment on the person who took my blood specimens during this visit left a sizeable bruise on my arm for several days which I thought was very unprofessional.
Dr. Shay was amazing. She listened to my concerns and we came up with a good plan of care. She's so kind and very knowledgeable too!
Listen carefully and explain clearly. Show empathy for the patient.
An absolutely superior doctor. She explains complicated medical issues in an understandable manner without making me fell as if I was a child. I could not think of a better doctor I have had in my life. And I have lived a long time.
Very knowledgeable about my situation ,and quick with solutions to solve the problem.
Everything was good