- Avascular Necrosis
Avascular necrosis develop when blood supply to a bone is cut off. This causes the bone to die and can cause pain and joint problems.
Anatomy of the Bone
A typical bone in your body contains three types of tissue—a hard outer tissue, a sponge-like inner tissue, and smooth tissue at the ends.
Detailed information on bone cancers, including chondrosarcoma, ewings sarcoma, myeloma bone disease, multiple myeloma, and osteosarcoma
Detailed information on bone disorders, including avascular necrosis, fibrous dysplasia, osteogenesis imperfecta, osteomyelitis, Paget's disease of the bone, and primary hyperparathyroidism
A chondroblastoma is a rare type of noncancerous bone tumor that begins in cartilage. This is the specialized, gristly connective tissue from which most bones develop. It plays an important role in the growth process. There are many different types of cartilage in the body. Chondroblastoma most often affects the ends of the long bones, near the growth plate, in the arms at the shoulder, and in the legs at the hip and knee. It is also called Codman’s tumor.
Chondrosarcoma is a malignant type of bone cancer that primarily affects the cartilage cells of the femur, arm, pelvis, knee, and spine.
Diagnosing Bone Disorders
Detailed information on diagnostic procedures for bone disorders, including bone densitometry, radionuclide bone scan, and biopsy
An enchondroma is a type of noncancerous bone tumor that begins in cartilage. An enchondroma most often affects the cartilage that lines the inside of the bones. It often affects the tiny long bones of the hands and feet. It may also affect other bones such as the femur (thighbone), humerus (upper arm bone), or tibia (one of the two lower leg bones).
Ewing Sarcoma in Adults
Ewing sarcoma can occur in any bone, but is most often found in the extremities and can involve muscle and the soft tissues around the tumor site.
Fibrous dysplasia is a chronic disorder in which an abnormal development of fibrous tissue causes bones to expand. Any bone can be affected. More than one bone can be affected at any one time, and, when multiple bones are affected, it is not unusual for them to all be on one side of the body. However, fibrous dysplasia does not spread from one bone to another.
Giant Cell Tumor
A giant cell tumor is one that is made up of a large number of benign (noncancerous) cells that form an aggressive tumor. It usually develops near a joint at the end of the bone. The location of a giant cell tumor is often in the knee, but can also involve the bones of the arms and the legs, or the flat bones such as the breastbone or pelvis.
Primary hyperparathyroidism is a metabolic disorder in which one or more of the parathyroid glands produces too much parathyroid hormone. This can result in a loss of bone tissue. A job of the parathyroid hormone is to keep blood calcium levels from going too low. This is done by releasing calcium from bones. The hormone also conserves calcium that would be excreted by the kidneys, and increases how much calcium is absorbed from food. When the hormone overacts, the result is a rise in the blood calcium level. Too much parathyroid hormone causes too much calcium to be released from bone.
Home Page - Bone Disorders
Detailed information on the anatomy of human bones and the most common bone disorders
Myeloma bone disease is cancer that affects certain white blood cells called plasma cells.
- Osteogenesis Imperfecta in Children
Osteogenesis imperfecta (OI) is an inherited disorder of the tissue that holds the body together (connective tissue). It is present at birth (congenital). A child born with OI may have signs and symptoms that range from mild to severe. He or she may have soft bones that break(fracture) easily, bones that are not formed normally, and other problems.
Online Resources - Bone Disorders
List of online resources to find additional information on bone disorders, including bone cancer
Osteochondroma is an overgrowth of cartilage and bone at the end of the bone near the growth plate. Most often, it affects the long bones in the leg, the pelvis, or the shoulder blade.
Osteomyelitis is an inflammation or swelling of bone tissue. It’s most often caused by an infection. Bone infection may occur for many reasons and can affect children or adults.
Osteosarcoma usually affects the long bones around the knee. It occurs most often in children, adolescents, and young adults.
- Paget Disease of the Bone
Paget disease of the bone is a chronic bone disorder. It causes bones to become enlarged and deformed. Bone may become dense, but fragile, because of excessive breakdown and deformation of bone. The disease is the most common bone disorder after osteoporosis in people over age 50.
Topic Index - Bone Disorders
Detailed information on the anatomy of human bones and the most common bone disorders, including avascular necrosis, fibrous dysplasia, osteogenesis imperfecta, osteomyelitis, Paget's disease of the bone, primary hyperparathyroidism, bone cancer, chondros
Benign Bone Tumors
Detailed information on the most common benign bone tumors, including chondroblastoma, enchondroma, giant cell tumor, and osteochondroma