Penile Cancer: Tests After Diagnosis

What tests might I have after being diagnosed?

After a diagnosis of penile cancer, you will likely have other tests. These tests help your healthcare providers learn more about your cancer. They can help show if the cancer has grown into nearby areas or spread to other parts of the body. The test results help your healthcare providers decide the best ways to treat the cancer. If you have any questions about these or other tests, be sure to talk with your healthcare team.

The tests you may have can include:

  • Ultrasound

  • CT scan

  • MRI

  • Sentinel lymph node biopsy

Imaging Tests


This test uses sound waves and a computer to create a picture of tissues in your body. No radiation is used. You will lie on a table. A technician will move a probe, or transducer, along your skin over your penis. The echoes that bounce back are picked up and made into an image on a computer screen. This test can also help tell how deeply a tumor has gone into (invaded) the penis.

CT scan

This test uses a series of X-rays from many angles. A computer puts the images together into one detailed image. You may need to drink a special X-ray dye, contrast medium, just before the scan. Or it may be injected into your vein through an IV or intravenous line. The dye helps images show up more clearly on the X-rays. The dye may cause a warm feeling in your face or chest. Tell your healthcare provider if you are allergic to or have had a reaction to X-ray dye.It can show if the lymph nodes are enlarged in the pelvis, abdomen, or both.


An MRI uses magnets, radio waves and a computer to make detailed pictures of the inside of the body. For this test, you lie still on a table as it slides into a tube-like scanner. If you are not comfortable in small spaces, you may be given a medicine to relax you before the test. This is called a sedative. The scanner directs a beam of radio waves at the area that is being checked. You may need more than 1 set of images. Each one may take 2 to 15 minutes. This test is painless, but it may take an hour or more. Like CT scans, MRIs can show enlarged lymph nodes in the abdomen or in the pelvis.


Sentinel lymph node biopsy

This is a type of biopsy that can help a doctor find the first lymph node (sentinel node) that drains from the tumor. If the sentinel node contains cancer, the surgeon may remove more lymph nodes. If the sentinel node does not have cancer, you don’t need to have other lymph nodes removed. Researchers are still testing this approach to obtaining lymph nodes.

Working with your healthcare provider

Your healthcare provider will talk with you about which tests you’ll have. Make sure to get ready for the tests as instructed. Ask questions and talk about any concerns you have.