Dec 03, 2020

Huntsman Cancer Institute Researchers Identify Promising Drug Combination for Melanoma

Researchers at Huntsman Cancer Institute at the University of Utah have identified a potential drug combination to treat uveal melanoma, a type of eye cancer. Lead author Amanda Truong, trainee in the McMahon Lab at HCI, explains uveal melanoma patients frequently have changes in genes called GNAQ and GNA11, which are key targets for these drugs. This study was published in the journal Clinical Cancer Research.

Nov 19, 2020

Scientists Discover Roles for a Cellular Motor in Cancer

Utah scientists have discovered new functions of a key cellular machine that regulates gene packaging and is mutated in 20% of human cancers. The study was published in print today in the journal Molecular Cell. Cairns and colleagues wanted to know how nucleosomes are moved along or removed from the DNA to unpackage and expose genes.

Oct 27, 2020

Letter of Hope: Breast and Ovarian Cancer Research in the Varley Lab

You might not see us during your visit to Huntsman Cancer Institute, but we want to let you know that we are working hard in the Varley Lab in the HCI research building next door. We conduct research that improves the treatment and care of patients like you. We are a small group of dedicated young men and women who are developing new strategies to diagnose and treat breast and ovarian cancer.

Oct 23, 2020

Fighting Adrenal Cancer through Less Toxic Treatments

In high school, Katie Basham received some news that would change her life—her mother was diagnosed with multiple myeloma. Basham headed down the only path she knew to make a difference for cancer patients, which was becoming a doctor. But she soon became intrigued by another path- developing better treatments for cancer. She transitioned her training to laboratory science, studying at the University of Utah and University of Michigan. The 5 For The Fight Fellowship is a “welcome home” present of sorts. She receives the fellowship as she returns to HCI to set up her own laboratory studying adrenal cancers.

Oct 22, 2020

Letter of Hope: Breast Cancer Research in the Welm Labs

Dear patients, please know this as you go through your breast cancer treatment journey. The dedicated technical staff, PhD students, and postdoctoral fellows in the Welm Labs continue to work hard every day (and night!) to bring new hope to people with metastatic breast cancer through innovative research, always with patients in mind.

Sep 10, 2020

Novel Discovery Challenges a Current Kidney Cancer Paradigm

Newly published research has reversed our understanding of an aspect of kidney tumor growth. Researchers at Huntsman Cancer Institute at the University of Utah discovered that two key proteins have opposite roles than what was previously believed.

Aug 04, 2020

Scientists Develop New Models to Accelerate Progress in Preventing Drug Resistance in Lung and Pancreas Cancers

Scientists at Huntsman Cancer Institute at the University of Utah report today the development of new models to study molecular characteristics of tumors of the lung and pancreas that are driven by mutations in a gene named NTRK1. The findings were published today in the journal Cell Reports.

Jul 29, 2020

Letter of Hope: Sarcoma Research in the KB Jones Lab

You may not see us during a visit to Huntsman Cancer Institute. But rest assured, we are working hard to learn more about sarcoma in the research building next door. We are committed to learning the most we can in order to do the best we can for every patient. Read this Letter of Hope to sarcoma patients and their loved ones, from the KB Jones Lab.