Dec 01, 2021

Sequencing of Bone Marrow DNA May Predict Leukemia Relapse After CAR-T Therapy With Sufficient Time to Intervene

In pediatric and young adult patients with acute lymphoblastic leukemia (ALL) treated with tisagenlecleucel (Kymriah), DNA sequencing-based detection accurately identified all patients who would eventually relapse, while other methods were less predictive, according to a study published in Blood Cancer Discovery, a journal of the American Association for Cancer Research.

Oct 13, 2021

Huntsman Cancer Institute Researcher Receives Grant to Study Pediatric Proton Therapy

Huntsman Cancer Institute physician and researcher Matthew Poppe, MD, received a National Cancer Institute grant to study side effects of different types of radiation—proton therapy and traditional radiation therapy—in the treatment of pediatric patients.

Sep 13, 2021

Pediatric Proton Therapy: What to Expect

If your child needs proton therapy to treat cancer, you may wonder what that means. Learn what proton therapy is and what to expect as your child goes through pediatric proton therapy treatment.

Aug 19, 2021

New Research Identifies Genomic Markers of Aggressive Childhood Leukemias

New research published today in JAMA Oncology reports how two separate DNA changes appear to predict aggressive childhood leukemias when they occur in combination. This study illuminates genetic understanding of acute lymphoblastic leukemia in children with the worst outcomes, including relapse and/or death.

Jun 23, 2021

Proton Therapy Opens in Utah

Patients, doctors, scientists, donors, and community members gathered on June 23, 2021 to mark the opening of a major new resource for cancer care in Utah. The Senator Orrin G. Hatch Proton Therapy Center at Huntsman Cancer Institute (HCI) is the first of its kind in the Mountain West and one of only 37 such centers nationwide.

Mar 03, 2021

Utah Researchers Illuminate Potential Precursors of Blood Cancers

Utah researchers report significant new insights into the development of blood cancers. Comparing DNA data in people with and without blood disorders, the researchers discovered genetic mutations in about 2% of the presumably healthy participants that were identical to those frequently observed in the cancer patients. These findings provide new clues about mutations that may initiate cancer development and those that may help cancer progress.

Oct 20, 2020

Talks with Docs: Samuel Cheshier, Pediatric Neurosurgeon

“I just love taking care of them, helping make them better,” says pediatric neurosurgeon Samuel Cheshier about the children he treats at Huntsman Cancer Institute and Primary Children’s Hospital. He talks about what he has learned from these kids and their parents, what patients should know about Huntsman Cancer Institute, and what he reads about in his spare time.

Oct 16, 2020

Fighting Brain Tumors in Kids

When Samuel Cheshier was 13 years old, his favorite cousin died of colon cancer. “I always think of him when I do cancer research,” Cheshier says. As a pediatric neurosurgeon, he witnesses firsthand the devastation that malignant brain tumors cause patients and their families. The desire to help them motivates his basic science research, with the goal of translating experiments into therapies. The 5 for the Fight Fellowship will help speed up the pace of his research, allowing him to start a new project.