High Risk Breast Clinic

Research Studies

HRBCC: The High Risk Breast Cancer Clinic (HRBCC), one of six sites that make up the Breast Cancer Family Registry (BCFR), serves as a resource for researchers searching for new ways to prevent, diagnose and treat cancer. Over a fifteen year period the HRBCC enrolled more than 1500 individuals from 256 families, collecting data and biospecimens that have been made available for research. Internationally, over 30,000 individuals from nearly 12,000 families have contributed data and/or biospecimens to this valuable resource that has resulted in hundreds of publications and research projects.

LEGACY: This is a study in which Huntsman Cancer Institute’s High Risk Breast Cancer Clinic (HRBCC) and the Family Cancer Assessment Clinic have joined four other Breast Cancer Family Registry (BCFR) sites to enroll adolescent girls into a research resource.  We are exploring early childhood lifestyles that might be important in determining the risks of developing breast cancer. In addition, to study these factors in a scientific manner, we have enrolled a ‘control’ group of girls who likely share the same environment, but not genetics. We are looking at environmental and biological factors that may differ among girls from different families affected by breast and ovarian cancer.  It will be important to know if these factors affect cancer risk later in life. 
For more information, please go to http://legacygirlsstudy.org/

IMPACT: Men who carry mutations in BRAC1 / BRACA2 seen to be at increased risk of developing prostate cancer, possibly enough to justify annual prostate specific antigen (PSA) screening for the disease. In addition, there is growing evidence that these men develop more aggressive types of prostate cancer at younger ages. These preliminary results of the IMPACT study (Identification of Men with a Genetic Predisposition to Prostate Cancer: Targeted screening in BRACA! And BRACA2 mutation carriers and controls) were published in the journal European Urology in January 2014. Huntsman Cancer Institute (HCI) is one of 62 research centers in 20 countries participating in the study, Nearly 2,500 men have enrolled overall, including 58 from HCI’s High Risk Breast Cancer Clinic.

BCFR: For over 16 Years, the HRBCC has been enrolling men and women over age 18 that have a personal or family history of breast cancer to participate in a research resource called the Breast Cancer Family Registry. 
For more information, please go to http://www.bcfamilyregistry.org/