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QBS Recruitment Weekend 2/26-2/27

We have invited an excellent group of students to interview for the Quantitative Biomedical Sciences Ph.D. program! We are looking forward to meeting them during Recruitment Weekend 2/26-2/27.


Check out our cross-population analysis of ovarian cancer subtypes

Greg has submitted his manuscript to Genome Medicine! We've posted a preprint of the manuscript HERE.


Munck-Pfefferkorn Awards

I am honored to be a Munck-Pfefferkorn grant awardee. These awards focus on translational research projects. Carmen Marsit and I are leading a project investigating the potential of blood-based biomarkers (genome-wide methylation and telomere length) to find people at particularly high risk of lung caner who might benefit from screening. A more detailed story was published on the Geisel school of medicine site HERE.


Great news on grant funding!

We received a lot of good news about grant funding in December. We have a new R01 to determine whether the poorer survival from ovarian cancer observed among women of African ancestry is due to a higher incidence of aggressive forms of the disease, and/or if survival is poorer even for less aggressive subtypes. The grant will focus on whole transcriptome-based and DNA sequencing-based subtypes, and we also received additional funding to examine methylation (COBRE award), and copy number alteration (Prouty award) in tumors from these women.


Congratulations James!

James' paper describing a method to select a reduced set of genes to assay for gene expression in order infer the expression of un-assayed genes is in press. It can be accessed HERE. It's a great read and should really help current and future studies in which measuring expression of the entire genome is infeasible.


NCCC Grand Rounds presentation

In case you are interested, my Norris Cotton Cancer Center grand rounds presentation entitled "Epidemiologic approaches to characterizing ovarian cancer subtypes" is available HERE.


QBS Student Potluck

We hosted a potluck dinner party for QBS students, faculty, family, and friends. There was such a great turn out; I think almost everyone in the program stopped by. It was great to connect outside of the science. And the food was truly incredible!


Recruiting students at the Annual Biomedical Research Conference for Minority Students

It was incredible to meet so many talented undergraduate scientists at the Annual Biomedical Research Conference for Minority Students in Seattle. As a poster judge, I had the chance to talk with a lot of students one-on-one about their research. I can't wait to go again next year!


Big Data Symposium

James presented our initial work interpreting the biological pathways that define subtypes of ovarian cancer at the 2015 Burroughs Wellcome Big Data Symposium. The symposium was sponsored by QBS and focused on the intersection of wet lab and computational sciences. As a poster presenter, James was entered into a raffle for an iPad and HE WON!! Congratulations James.


Nice article on our Mendelian randomization paper!

The NCCC wrote a feature article on our Mendelian randomization paper linking a genetic risk score for long telomere length to risk of lung adenocarcinoma. This work was a collaboration with Dr. Brandon Pierce and his PhD student Chenan Zhang at University of Chicago, through the NCI-sponsored GAME-ON initiative.


Good-bye to Emily, our MD-PhD Undergraduate Summer fellow

We enjoyed having Emily Shea, an MD-PhD Undergraduate Summer (MPUS) fellow, work with us this summer. Emily and James worked closely together to identify metagenes in ovarian cancer subtypes. Emily presented a poster and gave an oral presentation describing her work at the end of the summer. We celebrated everyone's accomplishments with a lab dinner.

Goodbye to Emily


American Association for Cancer Research Meeting

The Doherty lab was well represented at this year's AACR meeting. James, Greg, Sara and Jen had posters. So much fun!

Jen Doherty

Jen Doherty

Greg Way


Norris Cotton Cancer Center Retreat--Greg wins 2nd Place in the Poster Competition!

Go Greg! At our annual Norris Cotton Cancer Center retreat, Greg's rotation project poster on agnostically identifying ovarian cancer subtypes in distinct populations won the 2nd place award! Congradulations to Greg as we write up the findings in a manuscript.


James' F31 is Funded!!

Congratulations to James! All that hard work writing the NIH F31 pre-doctoral fellowship grant paid off since it was funded in the first submission!