Why Choose Us for PIPAC
Innovative, minimally invasive treatment for cancers in the abdominal cavity
Huntsman Cancer Institute is one of only a few hospitals in the country offering pressurized intraperitoneal aerosolized chemotherapy (PIPAC). This cutting‑edge treatment delivers chemotherapy directly to the lining of the abdominal cavity through laparoscopic surgery. Because this method is minimally invasive and uses chemotherapy where it is needed most, it can help reduce recovery time and side effects while improving quality of life. It can be used in concert with systemic treatment to maximize synergy of cancer therapy.
Our experienced surgical oncology team is internationally recognized for our expertise in treating advanced cancers of the abdomen. As a National Cancer Institute-designated Comprehensive Cancer Center, we bring together leading surgeons, medical oncologists, and supportive care specialists to guide each patient’s care with collaboration and compassion, so you can feel confident you are in the best hands.
“There is a tremendous commitment at Huntsman Cancer Institute to bringing new treatment options for patients, especially those who, not long ago, had very few choices. PIPAC opens up new options—and hope—for these patients.”
—T. Clark Gamblin, MD, MS, MBA, FACS, Surgeon, Huntsman Cancer Institute
Chief, Division of Surgical Oncology, University of Utah
What Is PIPAC?
PIPAC is a minimally invasive procedure that uses aerosolized chemotherapy to reach and kill cancer cells in the lining of the abdominal cavity.
During the procedure, a surgeon makes small laparoscopic incisions in the abdomen. Using a specialized device, chemotherapy is delivered as a fine, pressurized mist throughout the abdominal cavity. The medication remains present in the abdomen after completion. The entire process often takes less than two hours. Most patients are discharged within 24 hours following the procedure.
Benefits of PIPAC
- Minimally invasive—PIPAC uses small incisions instead of open surgery, which can mean shorter recovery times and improved quality of life.
- Targeted delivery—PIPAC focuses treatment directly where the cancer is, limiting how much chemotherapy circulates through the rest of the body.
- Designed for hard‑to‑reach cancer—The pressurized mist helps chemotherapy spread evenly and reach deeper into cancer tissue, particularly in areas that can be hard to treat with standard chemotherapy.
- Repeatable—PIPAC may be performed multiple times, allowing doctors to monitor response and adjust care as needed.
- Additional therapy—PIPAC offers an synergistic therapy to consider in concert with systemic chemotherapy and does not require a prolonged wait time for patients receiving chemotherapy.
Make an Appointment with a PIPAC Expert
To make an appointment with a PIPAC expert, fill out our appointment form or call 801-587-7000. Our team will determine if your insurance covers treatment at Huntsman Cancer Institute or if you need a referral from a primary care doctor.
External providers can refer a patient using the online referral form or by calling 801-587-7000 to speak to a patient registration specialist.
Frequently Asked Questions About PIPAC
Pressurized intraperitoneal aerosolized chemotherapy (PIPAC) is a minimally invasive way to deliver chemotherapy directly into the abdominal cavity, also called the peritoneal cavity. Using small, band aid-sized incisions, a specialized device delivers chemotherapy that is aerosolized and gently pressurized so it can spread evenly across this lining, targeting cancer where it is needed most.
Need help navigating your care? The Cancer Learning Center is here to support you with personalized guidance, resources, and answers to your questions.
PIPAC is typically used for people with advanced cancers within the abdomen that cannot be completely removed with surgery, such as cytoreduction and heated intraperitoneal chemotherapy (HIPEC) .
PIPAC may be an option for treating these cancers that have spread to the lining of the abdomen (the peritoneum):
We carefully evaluate each patient to determine whether PIPAC is the most appropriate option. If PIPAC is not right for you, we offer other specialized treatments and will work with you to identify the best path forward.
PIPAC is performed using minimally invasive surgery. Patients either spend one night in the hospital for observation or go home the same day.
Because the procedure uses small incisions, recovery is typically quicker than with major abdominal surgery. Many patients are able to return to normal activities within a short period of time.
PIPAC is often given multiple times, usually spaced six to eight weeks apart, depending on how a patient responds to treatment.
For patients traveling to Huntsman Cancer Institute for treatment, Patient and Family Housing provides affordable lodging.
Your care team will review potential risks and monitor you closely throughout treatment.
PIPAC delivers a higher dose of chemotherapy directly to the abdomen than can be administered systemically. The most common side effects are similar to other laparoscopic procedures and include the following:
- Abdominal discomfort
- Nausea
- Fatigue
Our Supportive Oncology and Survivorship team provides support, including pain and symptom management, to patients during and after cancer treatment.
Insurance coverage for PIPAC can vary depending on your insurance plan and individual circumstances.
If you have concerns about costs or coverage, our financial advocates are available to help guide you through the process.
