Participate In Our LASIK or PRK Studies

The John A. Moran Eye Center at University of Utah Health is conducting three new studies for participants interested in vision correction surgery, specifically LASIK and photorefractive keratectomy (PRK). These studies allow patients to receive surgery at a discounted rate. For more information or to participate, please call 801-213-0125.

1. LASIK Flap Study

Laser-assisted in Situ Keratomileusis (LASIK) has become the preferred corneal procedure to correct certain refractive errors. Refractive errors are errors in the focusing of the light by the eye. One of the major advancements in LASIK has been the introduction of Femtosecond Laser technology for flap creation. The flap is created to allow the surgeon to access the cornea directly.

The Femtosecond Laser technology provides different parameters and settings that can be changed according to the surgeon's preference. One such parameter is the side-cut angle. Currently, there are no studies comparing the safety and efficacy of the 70 and 110 side-cut angles in FS-LASIK.

Purpose: Compare Degrees of Side-Cut Angles

The purpose of this study is to compare 70 and 110 degrees side-cut angles on the same patient undergoing FS-LASIK. Performing different side-cut angles on a same individual will allow a direct comparison of outcomes. We hope this study will improve patient care for people who receive LASIK in the future.

2. PRK Steroid Study

In photo-ablation procedures, a laser is used to sculpt corneal tissue to correct refractive error and help improve your vision. During photorefractive keratectomy (PRK), the surface epithelium is removed, and the laser energy is applied to reshape the underlying corneal stroma. This procedure is FDA approved and used widely.

Post-Operative Pain

Because the surface layer of the cornea is removed during PRK, there can be post-operative pain and discomfort. Along with placing a bandage contact lens over the eye, we routinely prescribe topical non-steroidal anti-inflammatory drugs (NSAIDs) for the first few days after surgery to help decrease pain and discomfort. Oral NSAIDs, like ibuprofen, have excellent pain control effects and are used by some surgeons as part of their post-PRK medication regimen. There is currently no consensus on whether oral or topical NSAIDs are better for post-PRK pain and no study has looked at the medications head-to-head.

Purpose: Compare pain scores in patients taking topical or oral NSAIDs after PRK

We are conducting a prospective, randomized trial to compare pain scores of patients on different NSAID regimens after PRK. If no difference in efficacy is detected between the study groups, this study will support the use of either NSAID regimen after PRK. If there is a major difference in the efficacy or safety of these two regimens, this could influence post-refractive surgery treatment practices.

3. LASIK/PRK CONTOURA Study

Purpose: Compare outcomes of topography-guided laser-assisted in situ keratomileusis (LASIK) and phororefractive keratectomy (PRK) compared to wavefront optimized LASIK and PRK

We are studying the difference in results between eyes that have been treated with the standard procedure for laser vision correction (LASIK or PRK), called wavefront optimized treatment, compared to eyes treated with a new FDA approved treatment for laser vision correction. The new treatment is called topography-guided laser vision correction and it uses maps of the peaks and valleys of the surface of the eye to help determine the amount and location of laser treatment. Both procedures are FDA approved and are being performed widely across the United States. Both forms of treatment have shown excellent results in clinical trials for LASIK and PRK surgery. We are interested in studying the results of our treatments at the Moran Eye Center.

We want to understand if there are any small differences in results of these procedures as performed at our institution. National studies have shown that patients obtain excellent vision with either form of LASIK and either form of PRK treatment, but small differences in laser vision correction procedures can exist at individual institutions and we want to understand the results at our center. One of the best ways to study any potential differences is to look at fellow eyes in the same person that each receive a different type of treatment. This type of study has been done in the past at our institution and demonstrated that other forms of laser vision correction resulted in similar visual quality.

This involves taking a survey as well taking some extra photography or pictures of the eye, most of which are done as a standard part of the treatment course for laser refractive surgery.