Pages with Matching Tag "antibiotic-resistance"

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No Benefit Found in Using Broad-spectrum Antibiotics as Initial Pneumonia Treatment

February 26, 2020

Doctors who use drugs that target antibiotic-resistant bacteria as a first-line defense against pneumonia should probably reconsider this approach.

Health Care Providers A Major Contributor to Problem of Antibiotic Overuse

July 20, 2015

A study suggests that differences in the routines of individual providers drives variation in antibiotic prescribing more than differences in patient characteristics, standards of practice at different hospitals, or clinical settings (emergency department, primary care, urgent care). The report, led by the Veterans Affairs Salt Lake City Health Care System and the University of Utah and published in the Annals of Internal Medicine, is an important step toward understanding the problem of antibiotic overuse, a major public health concern given the rise in antibiotic-resistant “superbugs”.

Identification of a Much-Needed Drug Target Against MRSA, Gram-Positive Infections

February 02, 2015

Scientists at the University of Utah and the University of Georgia have uncovered a pharmacological target that could enable development of novel drugs against antibiotic-resistant pathogens, including Methicillin-resistant Staphylococcus aureus (MRSA) and other infectious Gram-positive organisms such as Listeria and Mycobacterium tuberculosis. The target was revealed upon discovery of a Gram-positive bacteria-specific pathway for making heme, an essential iron-carrying molecule. The findings were reported in the journal, Proceedings of the National Academy of Sciences (PNAS).