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Mapping the Genome Jungle: Unique Animal Traits Could Offer Insight into Human Disease

March 06, 2018

Scientists at University of Utah Health are using animals' unique traits to pinpoint regions of the human genome that might affect health. The results of this project are available in the March 6 issue of the journal Cell Reports.... Read more

Genomes in Flux: New Study Reveals Hidden Dynamics of Bird and Mammal DNA Evolution

February 06, 2017

Evolution is often thought of as a gradual remodeling of the genome, the genetic blueprints for building an organism. But in some instances it might be more appropriate to call it an overhaul. Over the past 100 million years, the human lineage has lost one-fifth of its DNA, while an even greater amount was added, report scientists at the University of Utah School of Medicine. Until now, the extent to which our genome has expanded and contracted had been underappreciated. ... Read more

Metagenomics Pathogen Detection Tool Could Change How Infectious Diseases Are Diagnosed

May 26, 2016

Scientists at the University of Utah, ARUP Laboratories, and IDbyDNA, Inc., have developed ultra-fast, meta-genomics analysis software called Taxonomer that dramatically improves the accuracy and speed of pathogen detection. In a paper published today in Genome Biology, the collaborators demonstrated the ability of Taxonomer to analyze the sequences of all nucleic acids in a clinical specimen (DNA and RNA) and to detect pathogens, as well as profile the patient’s gene expression, in a matter of minutes. ... Read more