February 09, 2015
Scientists have created a novel, long-lasting "smart" insulin that self-activates when blood sugar soars. Tests on mouse models for type 1 diabetes show that one injection works for a minimum of 14 hours, during which it can repeatedly and automatically lower blood sugar levels after simulated meals, mimicking blood sugar recovery in healthy mice. The finding represents an important advance in insulin therapy for diabetics and will be published Feb. 9 in PNAS Early Edition.