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Abdominal Cancers: The Warning Signs, Screening, and Prevention

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Abdominal Cancers: The Warning Signs, Screening, and Prevention

Jun 25, 2026

Abdominal cancers can affect many organs, including the colon, stomach, pancreas, liver, kidneys, ovaries, and uterus. While some cancers can be prevented through routine screenings and vaccinations, many abdominal cancers are difficult to detect because their symptoms often resemble common digestive complaints. Theresa Warner, MD, Deputy Director of Huntsman Cancer Institute, explains the different types of abdominal cancers, the importance of preventive care, and the warning signs that should never be ignored.

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    What is Abdominal Cancer?

    Interviewer: Abdominal cancers are one of the more common cancers that people can develop. Over 400,000 Americans will be diagnosed with abdominal cancer each year, but it can be one of the more challenging ones to detect early and get the treatment needed.

    So to help us kind of delve into the different types of cancers that can occur in that abdominal area, some of the symptoms, and maybe even some of the ways that we can prevent it, we're joined by Dr. Theresa Werner, the Deputy Director for the Huntsman Cancer Institute, who specializes in certain abdominal cancers.

    Now, let's start with just kind of the real basics. What are some of the common types of abdominal cancers, and why is early detection so crucial?

    Dr. Werner: I think when you think about abdominal cancers, people think about your gastrointestinal or your GI tract, number one. So if you think about the anatomy, that could be your lower esophagus, your stomach, your small intestine or small bowel, your large intestine, or your colon and your rectum, for example. And your pancreas is another organ important to the GI tract that's in there.

    So any of the cancers that start in any one of those areas is something that we would think about when we think about abdominal cancers. You can also think about other organs that are in there. Liver, for example. You can develop liver cancer. Your kidneys, for example, are there as well. And then if we think specifically of female patients, we think about the uterus as being a source of cancer, fallopian tubes, and ovaries, for example.

    So there are predominantly GI cancers. There's genital/urinary if you think about kidneys, for example, and then lastly would be gynecologic cancer. So any of those organs could turn into cancer.

    Screening and Vaccines That Can Reduce Abdominal Cancer Risk

    The most important thing to do would be to prevent cancer from happening in the first place. And so the best example we could think about is doing a colonoscopy, for example. Patients who have a colonoscopy will have a direct visualization of the inside of their colon, and the doctors will usually look for any polyps.

    Polyps are not cancer. They're actually benign lesions, but certain polyps can turn into cancer if they're left in there long enough. So if you're great and you do your colonoscopies and they remove the polyps, then you might not develop colon cancer, and that would be a way to prevent cancer from even happening in the first place. So that's an easy thing and part of our routine cancer screening that we do for patients.

    If we think about gynecologic cancers, for example, the cervix is the very bottom part of the uterus, and so primary prevention of a cervix cancer would include getting an HPV vaccine. So again, available to adolescents, women, and men, or girls and boys to prevent HPV, which is a known cause of cervical cancer. So, an easy way to prevent cancer.

    Recognizing Abdominal Cancer Symptoms

    If we think about some of the symptoms, these are things that . . . I really ask patients to be very aware of their bodies. Nobody's going to know your body and your symptoms and what's normal for you better than you yourself, right?

    Persistent Pain, Bleeding, or Changes in Bowel Habits

    So if we think about GI cancer, I think the tough thing is that many of these symptoms are really common in benign conditions. How many people have had a stomachache? How many people have cramping, bloating, or food poisoning? Maybe it's something that you ate, and it turned into diarrhea. So I tell patients the thing to really think about is a new symptom that is unusual for them, especially one that persists. So something that lasts one day and you get better and it goes away... probably not worrisome, right? But if you're like "Oh, I'm continuing to have this pain" or "I'm continuing to have blood in my stool," that is not normal. And so those are the things that would get you to go contact your physician right away and say, "Hey, this isn't normal."

    I'm not saying that that would turn into cancer, but it does warrant a further workup to make sure that we're not missing something more serious. So again, change in the caliber of your stool, for example. If you have blood in the stool, which we've already talked about, or let's say your stools are pencil thin, that may mean that there's something wrong in your colon, for example, that needs to be worked out. And again, we talked about sort of vague GI symptoms, which unfortunately are a presentation for a lot of abdominal cancers. So bloating, cramping, early satiety, meaning you get full faster, you can't eat as much, for example. Any of those symptoms that persist longer than a few days, I think, warrant a phone call or a discussion with your primary care doctor to talk about.

    Then that can proceed to further workup. And that might be blood work, a lab test, or it could be some kind of imaging like an X-ray or a CAT scan to look and see if something is wrong.

    Abnormal Bleeding and Other Gynecologic Cancer Warning Signs

    Also, if we think about the gynecologic cancers that are in the lower abdomen or pelvis, any abnormal bleeding, right? Women have menstrual cycles, but if your bleeding pattern is different or if you're postmenopausal and then all of a sudden you develop bleeding, that's a warning sign to come in and get checked out. That could mean that there's uterine cancer. So it would be an exam and maybe an ultrasound to look to see if something is going on.

    One of the other common abdominal cancers that we talk a lot about is ovarian cancer. It unfortunately has a bad reputation in the sense that it usually is diagnosed at very late stages. The reason is, number one, we don't have good screening for ovary cancer like we do for breast cancer, looking at a mammogram or a colonoscopy, just what we talked about with colon cancers. We don't have great screening for ovarian cancer, so we really rely on women to tell us if they're having symptoms.

    A lot of the ones that we talked about before, which are nonspecific early satiety, again getting full earlier, not being able to eat as much, bloating, cramping, abdominal pain, abnormal bleeding, all of these things. I've seen many patients who have come in and said, "I've been having these symptoms for months and just thought they were normal."

    When to Talk to Your Doctor About Abdominal Pain

    So again, it goes back to you knowing your body, and a symptom like that that persists for longer definitely warrants further evaluation. So that would be the message, I think, to patients is it's always scary when you think about, "Could I possibly have cancer?" But again, the earlier we find it, potentially the more treatable it is and the higher the chance that there is of a cure.

    So I just encourage patients to try not to be afraid and just come in and talk to their doctor about what could be going on. That's what we're here to do is to help sort of find out if there's anything serious going on that we need to intervene on.

     

    updated: June 25, 2026
    originally published: May 15, 2024